An experimental assay of the interactions of amino acids from orthologous sequences shaping a complex fitness landscape VO Pokusaeva, DR Usmanova, EV Putintseva, L Espinar, KS Sarkisyan, ... PLoS genetics 15 (4), e1008079, 2019 | 111 | 2019 |
Temporal competition between differentiation programs determines cell fate choice A Kuchina, L Espinar, T Çağatay, AO Balbin, F Zhang, A Alvarado, ... Molecular systems biology 7 (1), 557, 2011 | 93 | 2011 |
Uncovering de novo gene birth in yeast using deep transcriptomics WR Blevins, J Ruiz-Orera, X Messeguer, B Blasco-Moreno, ... Nature communications 12 (1), 604, 2021 | 80 | 2021 |
Slow-growing cells within isogenic populations have increased RNA polymerase error rates and DNA damage D Van Dijk, R Dhar, AM Missarova, L Espinar, WR Blevins, B Lehner, ... Nature communications 6 (1), 7972, 2015 | 56 | 2015 |
Reversible and noisy progression towards a commitment point enables adaptable and reliable cellular decision-making A Kuchina, L Espinar, J Garcia-Ojalvo, GM Süel PLoS computational biology 7 (11), e1002273, 2011 | 51 | 2011 |
Circuit-level input integration in bacterial gene regulation L Espinar, M Dies, T Çağatay, GM Süel, J Garcia-Ojalvo Proceedings of the National Academy of Sciences 110 (17), 7091-7096, 2013 | 31 | 2013 |
Promoter architecture determines cotranslational regulation of mRNA L Espinar, MÀS Tamarit, J Domingo, LB Carey Genome research 28 (4), 509-518, 2018 | 26 | 2018 |
A synthetic gene circuit for measuring autoregulatory feedback control MÀ Schikora-Tamarit, C Toscano-Ochoa, J Domingo Espinós, L Espinar, ... Integrative Biology 8 (4), 546-555, 2016 | 10 | 2016 |
Strand asymmetry influences mismatch resolution during single-strand annealing VO Pokusaeva, AR Diez, L Espinar, AT Pérez, GJ Filion Genome Biology 23 (1), 93, 2022 | 8* | 2022 |
Experimental assay of a fitness landscape on a macroevolutionary scale VO Pokusaeva, DR Usmanova, EV Putintseva, L Espinar, KS Sarkisyan, ... bioRxiv, 222778, 2017 | 8 | 2017 |
Frequent birth of de novo genes in the compact yeast genome WR Blevins, J Ruiz-Orera, X Messeguer, B Blasco-Moreno, ... bioRxiv, 575837, 2019 | 6 | 2019 |
Interactions between BRD4S, LOXL2, and MED1 drive cell cycle transcription in triple‐negative breast cancer L Pascual‐Reguant, Q Serra‐Camprubí, D Datta, D Cianferoni, S Kourtis, ... EMBO Molecular Medicine 15 (12), e18459, 2023 | 5 | 2023 |
Nuclear IMPDH2 controls the DNA damage response by modulating PARP1 activity L Espinar, M Garcia-Cao, A Schmidt, S Kourtis, A Gañez Zapater, ... Nature Communications 15 (1), 9515, 2024 | 1 | 2024 |
Nuclear localization of MTHFD2 is required for correct mitosis progression N Pardo-Lorente, A Gkanogiannis, L Cozzuto, A Gañez Zapater, ... Nature Communications 15 (1), 9529, 2024 | 1 | 2024 |
Nuclear MTHFD2 secures mitosis progression by preserving centromere integrity N Pardo-Lorente, A Gkanogiannis, L Cozzuto, AG Zapater, L Espinar, ... bioRxiv, 2023.06. 01.543193, 2023 | 1 | 2023 |
Nuclear metabolism oscillation during the cell cycle reveals a link between the phosphatidylinositol pathway and histone methylation. A Gañez-Zapater, S Kourtis, L Espinar, L García-López, L Wiegand, ... bioRxiv, 2024.12. 20.629614, 2024 | | 2024 |
Mitochondria-derived nuclear ATP surge protects against confinement-induced proliferation defects R Ghose, F Pezzano, S Kourtis, I Sheraj, S Das, AG Zapater, U Ghose, ... bioRxiv, 2023.12. 20.572417, 2023 | | 2023 |
Adaptation to ARF6-depletion in KRAS-driven PDAC is abolished by targeting TLR2 R Ghose, S Das, J Urgel-Solas, F Pezzano, D Datta, U Ghose, AG Zapater, ... bioRxiv, 2023.11. 30.569405, 2023 | | 2023 |
Interactions between BRD4 short, LOXL2, and MED1 drive cell cycle transcription in triple-negative breast cancer LP Reguant, TV Tian, D Datta, D Cianferoni, S Kourtis, A Gañez-Zapater, ... European Journal of Cancer 174, S61-S62, 2022 | | 2022 |
The BRD4S-LOXL2-MED1 interaction at the forefront of cell cycle transcriptional control in triple-negative breast cancer L Pascual-Reguant, TV Tian, D Datta, D Cianferoni, S Kourtis, ... bioRxiv, 2022.05. 27.493725, 2022 | | 2022 |