A direct interaction of cholesterol with the dopamine transporter prevents its out-to-inward transition T Zeppelin, LK Ladefoged, S Sinning, X Periole, B Schiøtt PLoS computational biology 14 (1), e1005907, 2018 | 92 | 2018 |
Monoamine transporters: insights from molecular dynamics simulations J Grouleff, LK Ladefoged, H Koldsø, B Schiøtt Frontiers in pharmacology 6, 235, 2015 | 82 | 2015 |
Binding of the multimodal antidepressant drug vortioxetine to the human serotonin transporter J Andersen, LK Ladefoged, D Wang, TNB Kristensen, B Bang-Andersen, ... ACS chemical neuroscience 6 (11), 1892-1900, 2015 | 30 | 2015 |
Binding-Induced Fluorescence of Serotonin Transporter Ligands: A Spectroscopic and Structural Study of 4-(4-(Dimethylamino)phenyl)-1-methylpyridinium (APP+) and APP … JN Wilson, LK Ladefoged, WM Babinchak, B Schiøtt ACS chemical neuroscience 5 (4), 296-304, 2014 | 26 | 2014 |
Interrogating the molecular basis for substrate recognition in serotonin and dopamine transporters with high-affinity substrate-based bivalent ligands J Andersen, LK Ladefoged, TNB Kristensen, L Munro, J Grouleff, ... ACS chemical neuroscience 7 (10), 1406-1417, 2016 | 24 | 2016 |
Modeling and mutational analysis of the binding mode for the multimodal antidepressant drug vortioxetine to the human 5-HT3A receptor LK Ladefoged, L Munro, AJ Pedersen, SCR Lummis, B Bang-Andersen, ... Molecular pharmacology 94 (6), 1421-1434, 2018 | 22 | 2018 |
A photoswitchable inhibitor of the human serotonin transporter B Cheng, J Morstein, LK Ladefoged, JB Maesen, B Schiøtt, S Sinning, ... ACS chemical neuroscience 11 (9), 1231-1237, 2020 | 20 | 2020 |
Substrate and inhibitor binding to the serotonin transporter: Insights from computational, crystallographic, and functional studies T Zeppelin, LK Ladefoged, S Sinning, B Schiøtt Neuropharmacology 161, 107548, 2019 | 19 | 2019 |
Conformational changes in the 5-HT3A receptor extracellular domain measured by voltage-clamp fluorometry L Munro, LK Ladefoged, V Padmanathan, S Andersen, B Schiøtt, ... Molecular Pharmacology 96 (6), 720-734, 2019 | 8 | 2019 |
Inhibitory effects of fluorinated benzenesulfonamides on insulin fibrillation SHA Janvand, LK Ladefoged, A Zubrienė, A Sakalauskas, G Christiansen, ... International Journal of Biological Macromolecules 227, 590-600, 2023 | 5 | 2023 |
Molecular modeling of neurological membrane proteins− from binding sites to synapses LK Ladefoged, T Zeppelin, B Schiøtt Neuroscience Letters 700, 38-49, 2019 | 4 | 2019 |
Divergent synthesis of new α-glucosidase inhibitors obtained through a vinyl Grignard-mediated carbocyclisation IMB Knudsen, C Hedberg, LK Ladefoged, D Ide, A Brinkø, EZ Eikeland, ... Organic & Biomolecular Chemistry 16 (34), 6250-6261, 2018 | 4 | 2018 |
Structural determinants for activity of the antidepressant vortioxetine at human and rodent 5-HT3 receptors U López-Sánchez, LJ Munro, LK Ladefoged, AJ Pedersen, CC Brun, ... Nature Structural & Molecular Biology 31 (8), 1232-1242, 2024 | 3 | 2024 |
Beneficent and Maleficent Effects of Cations on Bufadienolide Binding to Na+,K+-ATPase LK Ladefoged, B Schiøtt, NU Fedosova Journal of Chemical Information and Modeling 61 (2), 976-986, 2021 | 3 | 2021 |
Binding and activation of serotonergic G-protein coupled receptors by the multimodal antidepressant vortioxetine LK Ladefoged, R Koch, PC Biggin, B Schiøtt ACS Chemical Neuroscience 13 (8), 1129-1142, 2022 | 1 | 2022 |
Geometry and water accessibility of the inhibitor binding site of Na+-pump: Pulse-and CW-EPR study E Aloi, JH Guo, R Guzzi, RW Jiang, LK Ladefoged, D Marsh, M Esmann, ... Biophysical Journal 120 (13), 2679-2690, 2021 | 1 | 2021 |
Structural determinants for activity of the antidepressant vortioxetine at human and rodent 5-HT3 receptors (MAY, 10.1038/s41594-024-01282-x, 2024) U Lopez-Sanchez, LJ Munro, LK Ladefoged, AJ Pedersen, CC Brun, ... NATURE STRUCTURAL & MOLECULAR BIOLOGY 31 (7), 1145-1145, 2024 | | 2024 |
Author Correction: Structural determinants for activity of the antidepressant vortioxetine at human and rodent 5-HT3 receptors U López-Sánchez, LJ Munro, LK Ladefoged, AJ Pedersen, CC Brun, ... Nature structural & molecular biology 31 (7), 1145, 2024 | | 2024 |
Potentiation of drug toxicity through virus latency reversal promotes preferential elimination of HIV infected cells TT Truong, M Hayn, CK Frich, LR Olari, LK Ladefoged, MTJ Olesen, ... Advanced Therapeutics 5 (11), 2200113, 2022 | | 2022 |
Molecular Insight into the Agonist Properties of the Multimodal Antidepressant Vortioxetine in Human 5-HT3A Receptors LK Ladefoged, L Munro, AS Kristensen, B Schiøtt Biophysical Journal 116 (3), 479a, 2019 | | 2019 |