| Influence of sex on propofol metabolism, a pilot study: implications for propofol anesthesia I Loryan, M Lindqvist, I Johansson, M Hiratsuka, I Van Der Heiden, ... European journal of clinical pharmacology 68, 397-406, 2012 | 107 | 2012 |
| The brain slice method for studying drug distribution in the CNS I Loryan, M Fridén, M Hammarlund-Udenaes Fluids and Barriers of the CNS 10, 1-9, 2013 | 103 | 2013 |
| Mechanistic understanding of brain drug disposition to optimize the selection of potential neurotherapeutics in drug discovery I Loryan, V Sinha, C Mackie, A Van Peer, W Drinkenburg, A Vermeulen, ... Pharmaceutical research 31, 2203-2219, 2014 | 77 | 2014 |
| Unbound Brain-to-Plasma Partition Coefficient, Kp,uu,brain—a Game Changing Parameter for CNS Drug Discovery and Development I Loryan, A Reichel, B Feng, C Bundgaard, C Shaffer, C Kalvass, ... Pharmaceutical research 39 (7), 1321-1341, 2022 | 73 | 2022 |
| Molecular properties determining unbound intracellular and extracellular brain exposure of CNS drug candidates I Loryan, V Sinha, C Mackie, A Van Peer, WH Drinkenburg, A Vermeulen, ... Molecular pharmaceutics 12 (2), 520-532, 2015 | 69 | 2015 |
| In-depth neuropharmacokinetic analysis of antipsychotics based on a novel approach to estimate unbound target-site concentration in CNS regions: link to spatial receptor occupancy I Loryan, E Melander, M Svensson, M Payan, F König, B Jansson, ... Molecular Psychiatry, 2016 | 68 | 2016 |
| Sex difference in formation of propofol metabolites: a replication study E Choong, I Loryan, M Lindqvist, Å Nordling, S El Bouazzaoui, ... Basic & clinical pharmacology & toxicology 113 (2), 126-131, 2013 | 64 | 2013 |
| Rate and extent of mitragynine and 7‐hydroxymitragynine blood–brain barrier transport and their intra‐brain distribution: the missing link in pharmacodynamic studies SR Yusof, M Mohd Uzid, EH Teh, NA Hanapi, M Mohideen, ... Addiction Biology 24 (5), 935-945, 2019 | 42 | 2019 |
| UGT1A4*3 Encodes Significantly Increased Glucuronidation of Olanzapine in Patients on Maintenance Treatment and in Recombinant Systems T Haslemo, I Loryan, N Ueda, B Mannheimer, L Bertilsson, ... Clinical Pharmacology & Therapeutics 92 (2), 221-227, 2012 | 38 | 2012 |
| Effect of transporter inhibition on the distribution of cefadroxil in rat brain X Chen, I Loryan, M Payan, RF Keep, DE Smith, M Hammarlund-Udenaes Fluids and Barriers of the CNS 11, 1-12, 2014 | 33 | 2014 |
| Heterogeneous drug tissue binding in brain regions of rats, Alzheimer’s patients and controls: impact on translational drug development S Gustafsson, D Sehlin, E Lampa, M Hammarlund-Udenaes, I Loryan Scientific reports 9 (1), 5308, 2019 | 27 | 2019 |
| Neuropharmacokinetic visualization of regional and subregional unbound antipsychotic drug transport across the blood–brain barrier D Luptáková, T Vallianatou, A Nilsson, R Shariatgorji, ... Molecular psychiatry 26 (12), 7732-7745, 2021 | 26 | 2021 |
| Mechanistic Study on the Use of the l-Type Amino Acid Transporter 1 for Brain Intracellular Delivery of Ketoprofen via Prodrug: A Novel Approach Supporting the … E Puris, M Gynther, ECM de Lange, S Auriola, M Hammarlund-Udenaes, ... Molecular Pharmaceutics 16 (7), 3261-3274, 2019 | 26 | 2019 |
| Amorphisation of free acid ibuprofen and other profens in mixtures with nanocellulose: dry powder formulation strategy for enhanced solubility A Mantas, V Labbe, I Loryan, A Mihranyan Pharmaceutics 11 (2), 68, 2019 | 22 | 2019 |
| Molecular basis of mood and cognitive adverse events elucidated via a combination of pharmacovigilance data mining and functional enrichment analysis C Andronis, JP Silva, E Lekka, V Virvilis, H Carmo, K Bampali, M Ernst, ... Archives of toxicology 94 (8), 2829-2845, 2020 | 18 | 2020 |
| Quantitative assessment of drug delivery to tissues and association with phospholipidosis: a case study with two structurally related diamines in development I Loryan, E Hoppe, K Hansen, F Held, A Kless, K Linz, V Marossek, ... Molecular pharmaceutics 14 (12), 4362-4373, 2017 | 15 | 2017 |
| Brain distribution of drugs: Pharmacokinetic considerations I Loryan, M Hammarlund-Udenaes, S Syvänen Physiology, Pharmacology and Pathology of the Blood-Brain Barrier, 121-150, 2020 | 13 | 2020 |
| Drug discovery methods for studying brain drug delivery and distribution I Loryan, M Hammarlund-Udenaes Drug Delivery to the Brain: Physiological Concepts, Methodologies and …, 2013 | 11 | 2013 |
| Differential blood–brain barrier transport and cell uptake of cyclic peptides in vivo and in vitro E Melander, C Eriksson, S Wellens, K Hosseini, R Fredriksson, F Gosselet, ... Pharmaceutics 15 (5), 1507, 2023 | 8 | 2023 |
| Analysis of the contributing role of drug transport across biological barriers in the development and treatment of chemotherapy-induced peripheral neuropathy Y Hu, M Girdenyté, L Roest, I Liukkonen, M Siskou, F Bällgren, ... Fluids and Barriers of the CNS 21 (1), 13, 2024 | 7 | 2024 |
Margareta Hammarlund-UdenaesUppsala universityPreverjeni e-poštni naslov na farmbio.uu.se
