Martin Reijns

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Andrew P. JacksonUniversity of EdinburghPreverjeni e-poštni naslov na igmm.ed.ac.uk
Olga MurinaPostdoctoral Scientist, MRC Human Genetics Unit, IGMM, University of EdinburghPreverjeni e-poštni naslov na igmm.ed.ac.uk
Martin S. TaylorInstitute of Genetics and Cancer, University of EdinburghPreverjeni e-poštni naslov na ed.ac.uk
Žygimantė TarnauskaitėScientist, Insmed Innovation UK LtdPreverjeni e-poštni naslov na insmed.com
Nick GilbertEdinburgh UniversityPreverjeni e-poštni naslov na ed.ac.uk
Graeme GrimesMRC Human Genetics Unit, Institute of Genetics and Cancer, University of EdinburghPreverjeni e-poštni naslov na ed.ac.uk
Jean Beggsuniversity of edinburghPreverjeni e-poštni naslov na ed.ac.uk
Nelly OlovaResearch Fellow at the University of EdinburghPreverjeni e-poštni naslov na ed.ac.uk
Pleasantine MillMRC Human Genetics Unit, University of EdinburghPreverjeni e-poštni naslov na igmm.ed.ac.uk
i j holtBiodonostia Research InstitutePreverjeni e-poštni naslov na biodonostia.org
E Yvonne JonesThe Sir Andrew McMichael Professor of Structural Immunology, University of OxfordPreverjeni e-poštni naslov na strubi.ox.ac.uk
Stephen GrahamDepartment of Pathology, University of CambridgePreverjeni e-poštni naslov na cam.ac.uk
Doryen BubeckImperial College LonodnPreverjeni e-poštni naslov na imperial.ac.uk
Tatjana StankovicProfessor of Cancer GeneticsPreverjeni e-poštni naslov na bham.ac.uk
David ParryUniversity of EdinburghPreverjeni e-poštni naslov na ed.ac.uk
Kaalak ReddyThe RNA Institute - University at Albany, SUNYPreverjeni e-poštni naslov na albany.edu
Joseph A MarshProfessor of Computational Protein Biology, University of EdinburghPreverjeni e-poštni naslov na ed.ac.uk
angelo agathanggelouUniversity of BirminghamPreverjeni e-poštni naslov na bham.ac.uk
Traver HartThe University of Texas MD Anderson Cancer CenterPreverjeni e-poštni naslov na mdanderson.org
Jason MoffatSenior Scientist & Program Head, Genetics & Genome Biology, Sickkids Hospital; Professor, UofTPreverjeni e-poštni naslov na utoronto.ca

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Martin Reijns

Senior Lecturer, The University of Edinburgh

Preverjeni e-poštni naslov na ed.ac.uk - Domača stran

Molecular biology RNase H2 genome-embedded ribonucleotides mutagenesis nucleic acid mediated


Naslov Razvrsti po navedbah Razvrsti po letniku Razvrsti po naslovu	Navedeno Navedeno	Leto
cGAS surveillance of micronuclei links genome instability to innate immunity KJ Mackenzie, P Carroll, CA Martin, O Murina, A Fluteau, DJ Simpson, ... Nature 548 (7668), 461-465, 2017	1601	2017
Enzymatic removal of ribonucleotides from DNA is essential for mammalian genome integrity and development MAM Reijns, B Rabe, RE Rigby, P Mill, KR Astell, LA Lettice, S Boyle, ... Cell 149 (5), 1008-1022, 2012	538	2012
CRISPR screens identify genomic ribonucleotides as a source of PARP-trapping lesions M Zimmermann, O Murina, MAM Reijns, A Agathanggelou, R Challis, ... Nature 559 (7713), 285-289, 2018	389	2018
Lagging-strand replication shapes the mutational landscape of the genome MAM Reijns, H Kemp, J Ding, SM de Procé, AP Jackson, MS Taylor Nature 518 (7540), 502-506, 2015	267	2015
A role for Q/N-rich aggregation-prone regions in P-body localization MAM Reijns, RD Alexander, MP Spiller, JD Beggs Journal of cell science 121 (15), 2463-2472, 2008	261	2008
Ribonuclease H2 mutations induce a cGAS/STING‐dependent innate immune response KJ Mackenzie, P Carroll, L Lettice, Ž Tarnauskaitė, K Reddy, F Dix, ... The EMBO journal 35 (8), 831-844, 2016	253	2016
Defective removal of ribonucleotides from DNA promotes systemic autoimmunity C Günther, B Kind, MAM Reijns, N Berndt, M Martinez-Bueno, C Wolf, ... The Journal of clinical investigation 125 (1), 413-424, 2015	230	2015
Ribonucleotides misincorporated into DNA act as strand-discrimination signals in eukaryotic mismatch repair MM Ghodgaonkar, F Lazzaro, M Olivera-Pimentel, M Artola-Borán, ... Molecular cell 50 (3), 323-332, 2013	204	2013
Identification of VP19 and VP15 of white spot syndrome virus (WSSV) and glycosylation status of the WSSV major structural proteins MCW van Hulten, M Reijns, AMG Vermeesch, F Zandbergen, JM Vlak Journal of general virology 83 (1), 257-265, 2002	179	2002
RNA: DNA hybrids are a novel molecular pattern sensed by TLR9 RE Rigby, LM Webb, KJ Mackenzie, Y Li, A Leitch, MAM Reijns, ... The EMBO journal 33 (6), 542-558, 2014	171	2014
PCNA directs type 2 RNase H activity on DNA replication and repair substrates D Bubeck, MAM Reijns, SC Graham, KR Astell, EY Jones, AP Jackson Nucleic acids research 39 (9), 3652-3666, 2011	162	2011
cGAS-mediated induction of type I interferon due to inborn errors of histone pre-mRNA processing C Uggenti, A Lepelley, M Depp, AP Badrock, MP Rodero, MT El-Daher, ... Nature Genetics 52 (12), 1364-1372, 2020	160	2020
Gain-of-function DNMT3A mutations cause microcephalic dwarfism and hypermethylation of Polycomb-regulated regions P Heyn, CV Logan, A Fluteau, RC Challis, T Auchynnikava, CA Martin, ... Nature genetics 51 (1), 96-105, 2019	160	2019
Human and mouse mutations in WDR35 cause short-rib polydactyly syndromes due to abnormal ciliogenesis P Mill, PJ Lockhart, E Fitzpatrick, HS Mountford, EA Hall, MAM Reijns, ... The American Journal of Human Genetics 88 (4), 508-515, 2011	153	2011
The structure of the human RNase H2 complex defines key interaction interfaces relevant to enzyme function and human disease MAM Reijns, D Bubeck, LCD Gibson, SC Graham, GS Baillie, EY Jones, ... Journal of Biological Chemistry 286 (12), 10530-10539, 2011	118	2011
Mutations in DONSON disrupt replication fork stability and cause microcephalic dwarfism JJ Reynolds, LS Bicknell, P Carroll, MR Higgs, R Shaheen, JE Murray, ... Nature Genetics 49 (4), 537-549, 2017	108	2017
TRAIP promotes DNA damage response during genome replication and is mutated in primordial dwarfism ME Harley, O Murina, A Leitch, MR Higgs, LS Bicknell, G Yigit, ... Nature genetics 48 (1), 36-43, 2016	103	2016
DNA Polymerase Epsilon Deficiency Causes IMAGe Syndrome with Variable Immunodeficiency CV Logan, JE Murray, DA Parry, A Robertson, R Bellelli, Ž Tarnauskaitė, ... The American Journal of Human Genetics 103 (6), 1038-1044, 2018	87	2018
RNase H2, mutated in Aicardi‐Goutières syndrome, promotes LINE‐1 retrotransposition M Benitez‐Guijarro, C Lopez‐Ruiz, Ž Tarnauskaitė, O Murina, ... The EMBO journal 37 (15), e98506, 2018	83	2018
DNA damage contributes to neurotoxic inflammation in Aicardi-Goutières syndrome astrocytes AMS Giordano, M Luciani, F Gatto, M Abou Alezz, C Beghè, L Della Volpe, ... Journal of Experimental Medicine 219 (4), e20211121, 2022	64	2022

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