PEGylated DNA/transferrin–PEI complexes: reduced interaction with blood components, extended circulation in blood and potential for systemic gene delivery M Ogris, S Brunner, S Schüller, R Kircheis, E Wagner Gene therapy 6 (4), 595-605, 1999 | 1590 | 1999 |
The size of DNA/transferrin-PEI complexes is an important factor for gene expression in cultured cells M Ogris, P Steinlein, M Kursa, K Mechtler, R Kircheis, E Wagner Gene therapy 5 (10), 1425-1433, 1998 | 802 | 1998 |
Polylysine-based transfection systems utilizing receptor-mediated delivery W Zauner, M Ogris, E Wagner Advanced drug delivery reviews 30 (1-3), 97-113, 1998 | 743 | 1998 |
Purification of polyethylenimine polyplexes highlights the role of free polycations in gene transfer S Boeckle, K von Gersdorff, S van der Piepen, C Culmsee, E Wagner, ... The Journal of Gene Medicine: A cross‐disciplinary journal for research on …, 2004 | 572 | 2004 |
Polycation‐based DNA complexes for tumor‐targeted gene delivery in vivo R Kircheis, S Schüller, S Brunner, M Ogris, KH Heider, W Zauner, ... The journal of gene medicine 1 (2), 111-120, 1999 | 538 | 1999 |
Coupling of cell-binding ligands to polyethylenimine for targeted gene delivery R Kircheis, A Kichler, G Wallner, M Kursa, M Ogris, T Felzmann, ... Gene therapy 4 (5), 409-418, 1997 | 537 | 1997 |
Peptide-mediated RNA delivery: a novel approach for enhanced transfection of primary and post-mitotic cells T Bettinger, RC Carlisle, ML Read, M Ogris, LW Seymour Nucleic acids research 29 (18), 3882-3891, 2001 | 452 | 2001 |
Novel shielded transferrin− polyethylene glycol− polyethylenimine/DNA complexes for systemic tumor-targeted gene transfer M Kursa, GF Walker, V Roessler, M Ogris, W Roedl, R Kircheis, E Wagner Bioconjugate chemistry 14 (1), 222-231, 2003 | 433 | 2003 |
Toward synthetic viruses: endosomal pH-triggered deshielding of targeted polyplexes greatly enhances gene transfer in vitro and in vivo GF Walker, C Fella, J Pelisek, J Fahrmeir, S Boeckle, M Ogris, E Wagner Molecular Therapy 11 (3), 418-425, 2005 | 402 | 2005 |
Tumor-targeted gene therapy: strategies for the preparation of ligand–polyethylene glycol–polyethylenimine/DNA complexes M Ogris, G Walker, T Blessing, R Kircheis, M Wolschek, E Wagner Journal of Controlled Release 91 (1-2), 173-181, 2003 | 400 | 2003 |
The internalization route resulting in successful gene expression depends on both cell line and polyethylenimine polyplex type K Von Gersdorff, NN Sanders, R Vandenbroucke, SC De Smedt, ... Molecular therapy 14 (5), 745-753, 2006 | 397 | 2006 |
Importance of lateral and steric stabilization of polyelectrolyte gene delivery vectors for extended systemic circulation D Oupicky, M Ogris, KA Howard, PR Dash, K Ulbrich, LW Seymour Molecular Therapy 5 (4), 463-472, 2002 | 378 | 2002 |
Melittin enables efficient vesicular escape and enhanced nuclear access of nonviral gene delivery vectors M Ogris, RC Carlisle, T Bettinger, LW Seymour Journal of Biological Chemistry 276 (50), 47550-47555, 2001 | 319 | 2001 |
DNA/polyethylenimine transfection particles: influence of ligands, polymer size, and PEGylation on internalization and gene expression M Ogris, P Steinlein, S Carotta, S Brunner, E Wagner Aaps Pharmsci 3, 43-53, 2001 | 306 | 2001 |
Combination of hypoglycemia and metformin impairs tumor metabolic plasticity and growth by modulating the PP2A-GSK3β-MCL-1 axis M Elgendy, M Ciro, A Hosseini, J Weiszmann, L Mazzarella, E Ferrari, ... Cancer cell 35 (5), 798-815. e5, 2019 | 290 | 2019 |
Targeting tumors with non-viral gene delivery systems M Ogris, E Wagner Drug Discovery Today 7 (8), 479-485, 2002 | 245 | 2002 |
Synthesis and biological evaluation of a bioresponsive and endosomolytic siRNA− polymer conjugate M Meyer, C Dohmen, A Philipp, D Kiener, G Maiwald, C Scheu, M Ogris, ... Molecular pharmaceutics 6 (3), 752-762, 2009 | 244 | 2009 |
Cellular dynamics of EGF receptor–targeted synthetic viruses K De Bruin, N Ruthardt, K Von Gersdorff, R Bausinger, E Wagner, M Ogris, ... Molecular Therapy 15 (7), 1297-1305, 2007 | 226 | 2007 |
Liposome based systems for systemic siRNA delivery: stability in blood sets the requirements for optimal carrier design K Buyens, SC De Smedt, K Braeckmans, J Demeester, L Peeters, ... Journal of controlled release 158 (3), 362-370, 2012 | 224 | 2012 |
Melittin analogs with high lytic activity at endosomal pH enhance transfection with purified targeted PEI polyplexes S Boeckle, J Fahrmeir, W Roedl, M Ogris, E Wagner Journal of Controlled Release 112 (2), 240-248, 2006 | 201 | 2006 |