Long-term effects of Aβ42 immunisation in Alzheimer's disease: follow-up of a randomised, placebo-controlled phase I trial C Holmes, D Boche, D Wilkinson, G Yadegarfar, V Hopkins, A Bayer, ... The Lancet 372 (9634), 216-223, 2008 | 1888 | 2008 |
Microglia in neurodegenerative disease VH Perry, JAR Nicoll, C Holmes Nature Reviews Neurology 6 (4), 193-201, 2010 | 1882 | 2010 |
Neuropathology of human Alzheimer disease after immunization with amyloid-β peptide: a case report JAR Nicoll, D Wilkinson, C Holmes, P Steart, H Markham, RO Weller Nature medicine 9 (4), 448-452, 2003 | 1819 | 2003 |
Activation patterns of microglia and their identification in the human brain D Boche, VH Perry, JAR Nicoll Neuropathology and applied neurobiology 39 (1), 3-18, 2013 | 1134 | 2013 |
Association of apolipoprotein E polymorphism with outcome after head injury GM Teasdale, JAR Nicoll, G Murray, M Fiddes The Lancet 350 (9084), 1069-1071, 1997 | 850 | 1997 |
Toxicity evaluation of replication-competent herpes simplex virus (ICP 34.5 null mutant 1716) in patients with recurrent malignant glioma R Rampling, G Cruickshank, V Papanastassiou, J Nicoll, D Hadley, ... Gene therapy 7 (10), 859-866, 2000 | 747 | 2000 |
Solutes, but not cells, drain from the brain parenchyma along basement membranes of capillaries and arteries: significance for cerebral amyloid angiopathy and neuroimmunology RO Carare, M Bernardes‐Silva, TA Newman, AM Page, JAR Nicoll, ... Neuropathology and applied neurobiology 34 (2), 131-144, 2008 | 704 | 2008 |
Apolipoprotein E ε4 allele is associated with deposition of amyloid β-protein following head injury JAR Nicoll, GW Roberts, DI Graham Nature medicine 1 (2), 135-137, 1995 | 614 | 1995 |
Association of interleukin‐1 gene polymorphisms with Alzheimer's disease JAR Nicoll, RE Mrak, DI Graham, J Stewart, G Wilcock, S MacGowan, ... Annals of Neurology: Official Journal of the American Neurological …, 2000 | 520 | 2000 |
Recent advances in neurotrauma DI Graham, TK McIntosh, WL Maxwell, JAR Nicoll Journal of Neuropathology & Experimental Neurology 59 (8), 641-651, 2000 | 472 | 2000 |
The potential for efficacy of the modified (ICP 34.5−) herpes simplex virus HSV1716 following intratumoural injection into human malignant glioma: A proof of principle study V Papanastassiou, R Rampling, M Fraser, R Petty, D Hadley, J Nicoll, ... Gene therapy 9 (6), 398-406, 2002 | 419 | 2002 |
Neuronal cytoskeletal changes are an early consequence of repetitive head injury JF Geddes, GH Vowles, JAR Nicoll, T Revesz Acta neuropathologica 98, 171-178, 1999 | 406 | 1999 |
Consequence of Aβ immunization on the vasculature of human Alzheimer's disease brain D Boche, E Zotova, RO Weller, S Love, JW Neal, RM Pickering, ... Brain 131 (12), 3299-3310, 2008 | 404 | 2008 |
Perivascular drainage of solutes is impaired in the ageing mouse brain and in the presence of cerebral amyloid angiopathy CA Hawkes, W Härtig, J Kacza, R Schliebs, RO Weller, JA Nicoll, ... Acta neuropathologica 121, 431-443, 2011 | 393 | 2011 |
High frequency of apolipoprotein E ϵ2 allele in hemorrhage due to cerebral amyloid angiopathy JAR Nicoll, C Burnett, S Love, DI Graham, D Dewar, JW Ironside, ... Annals of neurology 41 (6), 716-721, 1997 | 360 | 1997 |
Microvasculature changes and cerebral amyloid angiopathy in Alzheimer’s disease and their potential impact on therapy RO Weller, D Boche, JAR Nicoll Acta neuropathologica 118, 87-102, 2009 | 356 | 2009 |
Aβ Species Removal After Aβ42 Immunization JAR Nicoll, E Barton, D Boche, JW Neal, I Ferrer, P Thompson, ... Journal of Neuropathology & Experimental Neurology 65 (11), 1040-1048, 2006 | 345 | 2006 |
The nature, distribution and causes of traumatic brain injury DI Graham, JH Adams, JAR Nicoll, WL Maxwell, TA Gennarelli Brain pathology 5 (4), 397-406, 1995 | 328 | 1995 |
Long-term intracerebral inflammatory response after traumatic brain injury SM Gentleman, PD Leclercq, L Moyes, DI Graham, C Smith, WST Griffin, ... Forensic science international 146 (2-3), 97-104, 2004 | 326 | 2004 |
Capillary and arterial cerebral amyloid angiopathy in Alzheimer's disease: defining the perivascular route for the elimination of amyloid β from the human brain SD Preston, PV Steart, A Wilkinson, JAR Nicoll, RO Weller Neuropathology and applied neurobiology 29 (2), 106-117, 2003 | 319 | 2003 |