| Nitric oxide directly activates calcium-dependent potassium channels in vascular smooth muscle VM Bolotina, S Najibi, JJ Palacino, PJ Pagano, RA Cohen Nature 368 (6474), 850-853, 1994 | 2198 | 1994 |
| Mitochondrial dysfunction and oxidative damage in parkin-deficient mice JJ Palacino, D Sagi, MS Goldberg, S Krauss, C Motz, M Wacker, J Klose, ... Journal of Biological Chemistry 279 (18), 18614-18622, 2004 | 1244 | 2004 |
| Parkin-deficient mice exhibit nigrostriatal deficits but not loss of dopaminergic neurons MS Goldberg, SM Fleming, JJ Palacino, C Cepeda, HA Lam, A Bhatnagar, ... Journal of Biological Chemistry 278 (44), 43628-43635, 2003 | 1108 | 2003 |
| Chronic inhibition of nitric oxide production accelerates neointima formation and impairs endothelial function in hypercholesterolemic rabbits. AJ Cayatte, JJ Palacino, K Horten, RA Cohen Arteriosclerosis and thrombosis: a journal of vascular biology 14 (5), 753-759, 1994 | 687 | 1994 |
| SMN2 splice modulators enhance U1–pre-mRNA association and rescue SMA mice J Palacino, SE Swalley, C Song, AK Cheung, L Shu, X Zhang, ... Nature chemical biology 11 (7), 511-517, 2015 | 453 | 2015 |
| Somatic mutational landscape of splicing factor genes and their functional consequences across 33 cancer types M Seiler, S Peng, AA Agrawal, J Palacino, T Teng, P Zhu, PG Smith, ... Cell reports 23 (1), 282-296. e4, 2018 | 431 | 2018 |
| Modulation of splicing catalysis for therapeutic targeting of leukemia with mutations in genes encoding spliceosomal proteins SCW Lee, H Dvinge, E Kim, H Cho, JB Micol, YR Chung, BH Durham, ... Nature medicine 22 (6), 672-678, 2016 | 394 | 2016 |
| Synthetic lethal and convergent biological effects of cancer-associated spliceosomal gene mutations SCW Lee, K North, E Kim, E Jang, E Obeng, SX Lu, B Liu, D Inoue, ... Cancer cell 34 (2), 225-241. e8, 2018 | 232 | 2018 |
| Direct association of presenilin-1 with β-catenin M Murayama, S Tanaka, J Palacino, O Murayama, T Honda, X Sun, ... FEBS letters 433 (1-2), 73-77, 1998 | 220 | 1998 |
| Enhanced role of potassium channels in relaxations to acetylcholine in hypercholesterolemic rabbit carotid artery S Najibi, CL Cowan, JJ Palacino, RA Cohen American Journal of Physiology-Heart and Circulatory Physiology 266 (5 …, 1994 | 162 | 1994 |
| Splicing modulators act at the branch point adenosine binding pocket defined by the PHF5A–SF3b complex T Teng, JHC Tsai, X Puyang, M Seiler, S Peng, S Prajapati, D Aird, ... Nature communications 8 (1), 15522, 2017 | 153 | 2017 |
| Potassium channel-mediated relaxation to acetylcholine in rabbit arteries. CL Cowan, JJ Palacino, S Najibi, RA Cohen The Journal of pharmacology and experimental therapeutics 266 (3), 1482-1489, 1993 | 135 | 1993 |
| Aldose reductase inhibition restores endothelial cell function in diabetic rabbit aorta B Tesfamariam, JJ Palacino, RM Weisbrod, RA Cohen Journal of cardiovascular pharmacology 21 (2), 205, 1993 | 109 | 1993 |
| Identification of NUB1 as a suppressor of mutant Huntingtin toxicity via enhanced protein clearance B Lu, I Al-Ramahi, A Valencia, Q Wang, F Berenshteyn, H Yang, ... Nature neuroscience 16 (5), 562-570, 2013 | 107 | 2013 |
| A novel human embryonic stem cell‐derived Huntington's disease neuronal model exhibits mutant huntingtin (mHTT) aggregates and soluble mHTT‐dependent neurodegeneration B Lu, J Palacino The FASEB Journal 27 (5), 1820-1829, 2013 | 96 | 2013 |
| A striatal-enriched intronic GPCR modulates huntingtin levels and toxicity Y Yao, X Cui, I Al-Ramahi, X Sun, B Li, J Hou, M Difiglia, J Palacino, ... Elife 4, e05449, 2015 | 85 | 2015 |
| Preservation of endothelium-dependent relaxation in atherosclerotic rabbit aorta by probucol BC Simon, CC Haudenschild, RA Cohen, J Palacino Journal of cardiovascular pharmacology 21 (6), 893-901, 1993 | 83 | 1993 |
| Regulation of apoptosis by presenilin 1 B Wolozin, P Alexander, J Palacino Neurobiology of aging 19 (1), S23-S27, 1998 | 76 | 1998 |
| Sensitivity to splicing modulation of BCL2 family genes defines cancer therapeutic strategies for splicing modulators D Aird, T Teng, CL Huang, E Pazolli, D Banka, K Cheung-Ong, C Eifert, ... Nature communications 10 (1), 137, 2019 | 72 | 2019 |
| Intrinsic resistance of neural stem cells to toxic metabolites may make them well suited for cell non‐autonomous disorders: Evidence from a mouse model of Krabbe leukodystrophy RM Taylor, JP Lee, JJ Palacino, KA Bower, J Li, MT Vanier, DA Wenger, ... Journal of neurochemistry 97 (6), 1585-1599, 2006 | 63 | 2006 |
