The signaling adaptor p62 is an important NF-κB mediator in tumorigenesis A Duran, JF Linares, AS Galvez, K Wikenheiser, JM Flores, MT Diaz-Meco, ... Cancer cell 13 (4), 343-354, 2008 | 665 | 2008 |
p62 is a key regulator of nutrient sensing in the mTORC1 pathway A Duran, R Amanchy, JF Linares, J Joshi, S Abu-Baker, A Porollo, ... Molecular cell 44 (1), 134-146, 2011 | 566 | 2011 |
Targeted disruption of the ζPKC gene results in the impairment of the NF-κB pathway M Leitges, L Sanz, P Martin, A Duran, U Braun, JF Garcı́a, F Camacho, ... Molecular cell 8 (4), 771-780, 2001 | 490 | 2001 |
p62, upregulated during preneoplasia, induces hepatocellular carcinogenesis by maintaining survival of stressed HCC-initiating cells A Umemura, F He, K Taniguchi, H Nakagawa, S Yamachika, ... Cancer cell 29 (6), 935-948, 2016 | 458 | 2016 |
Essential role of RelA Ser311 phosphorylation by ζPKC in NF‐κB transcriptional activation A Duran, MT Diaz‐Meco, J Moscat The EMBO journal, 2003 | 456 | 2003 |
The atypical PKC-interacting protein p62 is an important mediator of RANK-activated osteoclastogenesis A Durán, M Serrano, M Leitges, JM Flores, S Picard, JP Brown, J Moscat, ... Developmental cell 6 (2), 303-309, 2004 | 370 | 2004 |
Mature-onset obesity and insulin resistance in mice deficient in the signaling adapter p62 A Rodriguez, A Durán, M Selloum, MF Champy, FJ Diez-Guerra, ... Cell metabolism 3 (3), 211-222, 2006 | 358 | 2006 |
Metabolic reprogramming of stromal fibroblasts through p62-mTORC1 signaling promotes inflammation and tumorigenesis T Valencia, JY Kim, S Abu-Baker, J Moscat-Pardos, CS Ahn, ... Cancer cell 26 (1), 121-135, 2014 | 326 | 2014 |
K63 polyubiquitination and activation of mTOR by the p62-TRAF6 complex in nutrient-activated cells JF Linares, A Duran, T Yajima, M Pasparakis, J Moscat, MT Diaz-Meco Molecular cell 51 (3), 283-296, 2013 | 275 | 2013 |
Control of nutrient stress-induced metabolic reprogramming by PKCζ in tumorigenesis L Ma, Y Tao, A Duran, V Llado, A Galvez, JF Barger, EA Castilla, J Chen, ... Cell 152 (3), 599-611, 2013 | 207 | 2013 |
Role of ζPKC in B‐cell signaling and function P Martin, A Duran, S Minguet, ML Gaspar, MT Diaz‐Meco, P Rennert, ... The EMBO journal, 2002 | 194 | 2002 |
Increased serine and one-carbon pathway metabolism by PKCλ/ι deficiency promotes neuroendocrine prostate cancer M Reina-Campos, JF Linares, A Duran, T Cordes, A L'Hermitte, MG Badur, ... Cancer Cell 35 (3), 385-400. e9, 2019 | 185 | 2019 |
Tumour‐suppression activity of the proapoptotic regulator Par4 I García‐Cao, A Duran, M Collado, MJ Carrascosa, J Martín‐Caballero, ... EMBO reports 6 (6), 577-583, 2005 | 130 | 2005 |
Amino acid activation of mTORC1 by a PB1-domain-driven kinase complex cascade JF Linares, A Duran, M Reina-Campos, P Aza-Blanc, A Campos, J Moscat, ... Cell reports 12 (8), 1339-1352, 2015 | 127 | 2015 |
A functional role for the p62–ERK1 axis in the control of energy homeostasis and adipogenesis SJ Lee, PT Pfluger, JY Kim, R Nogueiras, A Duran, G Pagès, ... EMBO reports 11 (3), 226-232, 2010 | 123 | 2010 |
PKCλ/ι loss induces autophagy, oxidative phosphorylation, and NRF2 to promote liver cancer progression Y Kudo, M Sugimoto, E Arias, H Kasashima, T Cordes, JF Linares, ... Cancer cell 38 (2), 247-262. e11, 2020 | 114 | 2020 |
ATF4-induced metabolic reprograming is a synthetic vulnerability of the p62-deficient tumor stroma JF Linares, T Cordes, A Duran, M Reina-Campos, T Valencia, CS Ahn, ... Cell metabolism 26 (6), 817-829. e6, 2017 | 114 | 2017 |
Adipocyte p62/SQSTM1 suppresses tumorigenesis through opposite regulations of metabolism in adipose tissue and tumor J Huang, A Duran, M Reina-Campos, T Valencia, EA Castilla, TD Müller, ... Cancer cell 33 (4), 770-784. e6, 2018 | 109 | 2018 |
Protein kinase Cζ represses the interleukin-6 promoter and impairs tumorigenesis in vivo AS Galvez, A Duran, JF Linares, P Pathrose, EA Castilla, S Abu-Baker, ... Molecular and cellular biology 29 (1), 104-115, 2009 | 103 | 2009 |
NRF2 activates growth factor genes and downstream AKT signaling to induce mouse and human hepatomegaly F He, L Antonucci, S Yamachika, Z Zhang, K Taniguchi, A Umemura, ... Journal of hepatology 72 (6), 1182-1195, 2020 | 99 | 2020 |