Controlling the physical behavior and biological performance of liposome formulations through use of surface grafted poly (ethylene glycol) C Allen, N Dos Santos, R Gallagher, GNC Chiu, Y Shu, WM Li, ... Bioscience reports 22, 225-250, 2002 | 529 | 2002 |
Ratiometric dosing of anticancer drug combinations: controlling drug ratios after systemic administration regulates therapeutic activity in tumor-bearing mice LD Mayer, TO Harasym, PG Tardi, NL Harasym, CR Shew, SA Johnstone, ... Molecular cancer therapeutics 5 (7), 1854-1863, 2006 | 411 | 2006 |
In vivo maintenance of synergistic cytarabine: daunorubicin ratios greatly enhances therapeutic efficacy P Tardi, S Johnstone, N Harasym, S Xie, T Harasym, N Zisman, P Harvie, ... Leukemia research 33 (1), 129-139, 2009 | 404 | 2009 |
Surface-associated serum proteins inhibit the uptake of phosphatidylserine and poly (ethylene glycol) liposomes by mouse macrophages SA Johnstone, D Masin, L Mayer, MB Bally Biochimica et Biophysica Acta (BBA)-Biomembranes 1513 (1), 25-37, 2001 | 166 | 2001 |
Coencapsulation of irinotecan and floxuridine into low cholesterol-containing liposomes that coordinate drug release in vivo PG Tardi, RC Gallagher, S Johnstone, N Harasym, M Webb, MB Bally, ... Biochimica et Biophysica Acta (BBA)-Biomembranes 1768 (3), 678-687, 2007 | 165 | 2007 |
In vitro characterization of the anticancer activity of membrane-active cationic peptides. I. Peptide-mediated cytotoxicity and peptide-enhanced cytotoxic activity of … SA Johnstone, K Gelmon, LD Mayer, RE Hancock, MB Bally Anti-cancer drug design 15 (2), 151-160, 2000 | 163 | 2000 |
Modulating the therapeutic activity of nanoparticle delivered paclitaxel by manipulating the hydrophobicity of prodrug conjugates SM Ansell, SA Johnstone, PG Tardi, L Lo, S Xie, Y Shu, TO Harasym, ... Journal of medicinal chemistry 51 (11), 3288-3296, 2008 | 159 | 2008 |
Drug ratio–dependent antitumor activity of irinotecan and cisplatin combinations in vitro and in vivo PG Tardi, N Dos Santos, TO Harasym, SA Johnstone, N Zisman, ... Molecular cancer therapeutics 8 (8), 2266-2275, 2009 | 154 | 2009 |
Phosphorylation of annexin II tetramer by protein kinase C inhibits aggregation of lipid vesicles by the protein. SA Johnstone, I Hubaishy, DM Waisman Journal of Biological Chemistry 267 (36), 25976-25981, 1992 | 121 | 1992 |
Liposome loading with metal ions P Tardi, S Johnstone, M Webb, M Bally, S Abraham US Patent 7,238,367, 2007 | 99 | 2007 |
Increased preclinical efficacy of irinotecan and floxuridine coencapsulated inside liposomes is associated with tumor delivery of synergistic drug ratios TO Harasym, PG Tardi, NL Harasym, P Harvie, SA Johnstone, LD Mayer Oncology research 16 (8), 361-374, 2007 | 94 | 2007 |
Autoantibodies to the centrosome (centriole) react with determinants present in the glycolytic enzyme enolase. JB Rattner, L Martin, DM Waisman, SA Johnstone, MJ Fritzler Journal of immunology (Baltimore, Md.: 1950) 146 (7), 2341-2344, 1991 | 61 | 1991 |
Enolase is present at the centrosome of HeLa cells SA Johnstone, DM Waisman, JB Rattner Experimental cell research 202 (2), 458-463, 1992 | 46 | 1992 |
Taxane delivery system SM Ansell, S Johnstone, P Tardi, L Mayer US Patent 8,486,924, 2013 | 45 | 2013 |
Liposomal formulations of anthracycline agents and cytidine analogs L Mayer, S Johnstone, T Harasym US Patent 8,022,279, 2011 | 45 | 2011 |
In vitro and in vivo characterization of a combination chemotherapy formulation consisting of vinorelbine and phosphatidylserine MS Webb, S Johnstone, TJ Morris, A Kennedy, R Gallagher, N Harasym, ... European journal of pharmaceutics and biopharmaceutics 65 (3), 289-299, 2007 | 44 | 2007 |
Optimizing liposomal cisplatin efficacy through membrane composition manipulations N Zisman, N Dos Santos, S Johnstone, A Tsang, D Bermudes, L Mayer, ... Chemotherapy Research and Practice 2011 (1), 213848, 2011 | 39 | 2011 |
Platinum drug formulations P Tardi, S Johnstone, L Mayer US Patent App. 14/931,679, 2016 | 38 | 2016 |
Regulation of annexin I-dependent aggregation of phospholipid vesicles by protein kinase C SA Johnstone, I Hubaishy, DM Waisman Biochemical Journal 294 (3), 801-807, 1993 | 37 | 1993 |
Liposomal formulations of anthracycline agents and cytidine analogs L Mayer, S Johnstone, T Harasym US Patent 8,431,806, 2013 | 32 | 2013 |