Affinity-based proteomics reveal cancer-specific networks coordinated by Hsp90 K Moulick, JH Ahn, H Zong, A Rodina, L Cerchietti, EM Gomes DaGama, ... Nature chemical biology 7 (11), 818-826, 2011 | 307 | 2011 |
BCL6 orchestrates Tfh cell differentiation via multiple distinct mechanisms K Hatzi, JP Nance, MA Kroenke, M Bothwell, EK Haddad, A Melnick, ... Journal of Experimental Medicine 212 (4), 539-553, 2015 | 288 | 2015 |
CREBBP Inactivation Promotes the Development of HDAC3-Dependent Lymphomas Y Jiang, A Ortega-Molina, H Geng, HY Ying, K Hatzi, S Parsa, D McNally, ... Cancer discovery 7 (1), 38-53, 2017 | 272 | 2017 |
Chronic lymphocytic leukemia cells recognize conserved epitopes associated with apoptosis and oxidation R Catera, GJ Silverman, K Hatzi, T Seiler, S Didier, L Zhang, M Hervé, ... Molecular medicine 14, 665-674, 2008 | 268 | 2008 |
EZH2 and BCL6 cooperate to assemble CBX8-BCOR complex to repress bivalent promoters, mediate germinal center formation and lymphomagenesis W Béguelin, M Teater, MD Gearhart, MTC Fernández, RL Goldstein, ... Cancer cell 30 (2), 197-213, 2016 | 244 | 2016 |
Chronic lymphocytic leukemia antibodies with a common stereotypic rearrangement recognize nonmuscle myosin heavy chain IIA CC Chu, R Catera, K Hatzi, XJ Yan, L Zhang, XB Wang, HM Fales, ... Blood, The Journal of the American Society of Hematology 112 (13), 5122-5129, 2008 | 234 | 2008 |
A purine scaffold Hsp90 inhibitor destabilizes BCL-6 and has specific antitumor activity in BCL-6–dependent B cell lymphomas LC Cerchietti, EC Lopes, SN Yang, K Hatzi, KL Bunting, LA Tsikitas, ... Nature medicine 15 (12), 1369-1376, 2009 | 208 | 2009 |
A peptomimetic inhibitor of BCL6 with potent antilymphoma effects in vitro and in vivo LC Cerchietti, SN Yang, R Shaknovich, K Hatzi, JM Polo, A Chadburn, ... Blood, The Journal of the American Society of Hematology 113 (15), 3397-3405, 2009 | 200 | 2009 |
BCL6-mediated repression of p53 is critical for leukemia stem cell survival in chronic myeloid leukemia C Hurtz, K Hatzi, L Cerchietti, M Braig, E Park, Y Kim, S Herzog, ... Journal of Experimental Medicine 208 (11), 2163-2174, 2011 | 197 | 2011 |
A hybrid mechanism of action for BCL6 in B cells defined by formation of functionally distinct complexes at enhancers and promoters K Hatzi, Y Jiang, C Huang, F Garrett-Bakelman, MD Gearhart, ... Cell reports 4 (3), 578-588, 2013 | 195 | 2013 |
Breaking bad in the germinal center: how deregulation of BCL6 contributes to lymphomagenesis K Hatzi, A Melnick Trends in molecular medicine 20 (6), 343-352, 2014 | 183 | 2014 |
Immunoglobulin light chain repertoire in chronic lymphocytic leukemia K Stamatopoulos, C Belessi, A Hadzidimitriou, T Smilevska, E Kalagiakou, ... Blood 106 (10), 3575-3583, 2005 | 166 | 2005 |
Rationally designed BCL6 inhibitors target activated B cell diffuse large B cell lymphoma MG Cardenas, W Yu, W Beguelin, MR Teater, H Geng, RL Goldstein, ... The Journal of clinical investigation 126 (9), 3351-3362, 2016 | 163 | 2016 |
A different ontogenesis for chronic lymphocytic leukemia cases carrying stereotyped antigen receptors: molecular and computational evidence N Darzentas, A Hadzidimitriou, F Murray, K Hatzi, P Josefsson, ... Leukemia 24 (1), 125-132, 2010 | 156 | 2010 |
The SS18-SSX oncoprotein hijacks KDM2B-PRC1. 1 to drive synovial sarcoma A Banito, X Li, AN Laporte, JS Roe, F Sanchez-Vega, CH Huang, ... Cancer cell 33 (3), 527-541. e8, 2018 | 147 | 2018 |
BCL6 repression of EP300 in human diffuse large B cell lymphoma cells provides a basis for rational combinatorial therapy LC Cerchietti, K Hatzi, E Caldas-Lopes, SN Yang, ME Figueroa, RD Morin, ... The Journal of clinical investigation 120 (12), 4569-4582, 2010 | 147 | 2010 |
Lineage-specific functions of Bcl-6 in immunity and inflammation are mediated by distinct biochemical mechanisms C Huang, K Hatzi, A Melnick Nature immunology 14 (4), 380-388, 2013 | 143 | 2013 |
Multi-tiered reorganization of the genome during B cell affinity maturation anchored by a germinal center-specific locus control region KL Bunting, TD Soong, R Singh, Y Jiang, W Béguelin, DW Poloway, ... Immunity 45 (3), 497-512, 2016 | 140 | 2016 |
Genome-wide analysis of DNA binding and transcriptional regulation by the mammalian Doublesex homolog DMRT1 in the juvenile testis MW Murphy, AL Sarver, D Rice, K Hatzi, K Ye, A Melnick, LL Heckert, ... Proceedings of the National Academy of Sciences 107 (30), 13360-13365, 2010 | 125 | 2010 |
DNA methylation profiling in human B cells reveals immune regulatory elements and epigenetic plasticity at Alu elements during B-cell activation AY Lai, D Mav, R Shah, SA Grimm, D Phadke, K Hatzi, A Melnick, ... Genome research 23 (12), 2030-2041, 2013 | 107 | 2013 |