The structure of the G protein heterotrimer Giα1β1γ2 MA Wall, DE Coleman, E Lee, JA Iñiguez-Lluhi, BA Posner, AG Gilman, ... Cell 83 (6), 1047-1058, 1995 | 1498 | 1995 |
G protein mechanisms: insights from structural analysis SR Sprang Annual review of biochemistry 66 (1), 639-678, 1997 | 1455 | 1997 |
Structures of Active Conformations of Giα1 and the Mechanism of GTP Hydrolysis DE Coleman, AM Berghuis, E Lee, ME Linder, AG Gilman, SR Sprang Science 265 (5177), 1405-1412, 1994 | 1137 | 1994 |
Crystal structure of the catalytic domains of adenylyl cyclase in a complex with Gsα· GTPγS JJG Tesmer, RK Sunahara, AG Gilman, SR Sprang Science 278 (5345), 1907-1916, 1997 | 1040 | 1997 |
Structure of RGS4 bound to AlF4−-activated Giα1: stabilization of the transition state for GTP hydrolysis JJG Tesmer, DM Berman, AG Gilman, SR Sprang Cell 89 (2), 251-261, 1997 | 1017 | 1997 |
The structure of tumor necrosis factor-α at 2.6 Å resolution: Implications for receptor binding MJ Eck, SR Sprang Journal of Biological Chemistry 264 (29), 17595-17605, 1989 | 937 | 1989 |
Structure of the first C2 domain of synaptotagmin I: a novel Ca2+/phospholipid-binding fold RB Sutton, BA Davletov, AM Berghuis, TC Sudhof, SR Sprang Cell 80 (6), 929-938, 1995 | 933 | 1995 |
Affinity panning of a library of peptides displayed on bacteriophages reveals the binding specificity of BiP S Blond-Elguindi, SE Cwirla, WJ Dower, RJ Lipshutz, SR Sprang, ... Cell 75 (4), 717-728, 1993 | 876 | 1993 |
Modularity in the TNF-receptor family JH Naismith, SR Sprang Trends in biochemical sciences 23 (2), 74-79, 1998 | 416 | 1998 |
Crystal structure of the adenylyl cyclase activator Gsα RK Sunahara, JJG Tesmer, AG Gilman, SR Sprang Science 278 (5345), 1943-1947, 1997 | 412 | 1997 |
Tertiary and quaternary structural changes in Giα1 induced by GTP hydrolysis MB Mixon, E Lee, DE Coleman, AM Berghuis, AG Gilman, SR Sprang Science 270 (5238), 954-960, 1995 | 411 | 1995 |
Two-metal-ion catalysis in adenylyl cyclase JJG Tesmer, RK Sunahara, RA Johnson, G Gosselin, AG Gilman, ... Science 285 (5428), 756-760, 1999 | 401 | 1999 |
Structural changes in glycogen phosphorylase induced by phosphorylation SR Sprang, KR Acharya, EJ Goldsmith, DI Stuart, K Varvill, RJ Fletterick, ... Nature 336 (6196), 215-221, 1988 | 379 | 1988 |
Three-dimensional structure of human basic fibroblast growth factor, a structural homolog of interleukin 1 beta. JD Zhang, LS Cousens, PJ Barr, SR Sprang Proceedings of the National Academy of Sciences 88 (8), 3446-3450, 1991 | 369 | 1991 |
Cytokine structural taxonomy and mechanisms of receptor engagement: Current opinion in structural biology 1993, 3: 815–827 SR Sprang, JF Bazan Current opinion in structural biology 3 (6), 815-827, 1993 | 355 | 1993 |
The three-dimensional structure of Asn102 mutant of trypsin: role of Asp102 in serine protease catalysis S Sprang, T Standing, RJ Fletterick, RM Stroud, J Finer-Moore, NH Xuong, ... Science 237 (4817), 905-909, 1987 | 290 | 1987 |
Exchange of substrate and inhibitor specificities between adenylyl and guanylyl cyclases RK Sunahara, A Beuve, JJG Tesmer, SR Sprang, DL Garbers, AG Gilman Journal of Biological Chemistry 273 (26), 16332-16338, 1998 | 285 | 1998 |
The structure of human lymphotoxin (tumor necrosis factor-beta) at 1.9-A resolution. MJ Eck, M Ultsch, E Rinderknecht, AM De Vos, SR Sprang Journal of Biological Chemistry 267 (4), 2119-2122, 1992 | 285 | 1992 |
Crystallographic Evidence for Dimerization of Unliganded Tumor Necrosis Factor Receptor∗ JH Naismith, TQ Devine, BJ Brandhuber, SR Sprang Journal of Biological Chemistry 270 (22), 13303-13307, 1995 | 239 | 1995 |
Structure of the protein kinase Cβ phospholipid-binding C2 domain complexed with Ca2+ RB Sutton, SR Sprang Structure 6 (11), 1395-1405, 1998 | 231 | 1998 |