Efficacy and safety of imatinib mesylate in advanced gastrointestinal stromal tumors GD Demetri, M Von Mehren, CD Blanke, AD Van den Abbeele, ... New England Journal of Medicine 347 (7), 472-480, 2002 | 5573 | 2002 |
Efficacy and safety of sunitinib in patients with advanced gastrointestinal stromal tumour after failure of imatinib: a randomised controlled trial GD Demetri, AT van Oosterom, CR Garrett, ME Blackstein, MH Shah, ... The Lancet 368 (9544), 1329-1338, 2006 | 3255 | 2006 |
PDGFRA activating mutations in gastrointestinal stromal tumors MC Heinrich, CL Corless, A Duensing, L McGreevey, CJ Chen, N Joseph, ... Science 299 (5607), 708-710, 2003 | 3081 | 2003 |
Kinase mutations and imatinib response in patients with metastatic gastrointestinal stromal tumor MC Heinrich, CL Corless, GD Demetri, CD Blanke, M Von Mehren, ... Journal of clinical oncology 21 (23), 4342-4349, 2003 | 2905 | 2003 |
Biology of gastrointestinal stromal tumors CL Corless, JA Fletcher, MC Heinrich Journal of Clinical Oncology 22 (18), 3813-3825, 2004 | 1695 | 2004 |
Inhibition of c-kit receptor tyrosine kinase activity by STI 571, a selective tyrosine kinase inhibitor MC Heinrich, DJ Griffith, BJ Druker, CL Wait, KA Ott, AJ Zigler Blood, The Journal of the American Society of Hematology 96 (3), 925-932, 2000 | 1393 | 2000 |
In vitro Activity of Bcr-Abl Inhibitors AMN107 and BMS-354825 against Clinically Relevant Imatinib-Resistant Abl Kinase Domain Mutants T O'Hare, DK Walters, EP Stoffregen, T Jia, PW Manley, J Mestan, ... Cancer research 65 (11), 4500-4505, 2005 | 1382 | 2005 |
Phase III randomized, intergroup trial assessing imatinib mesylate at two dose levels in patients with unresectable or metastatic gastrointestinal stromal tumors expressing the … CD Blanke, C Rankin, GD Demetri, CW Ryan, M Von Mehren, ... Journal of clinical oncology 26 (4), 626-632, 2008 | 1365 | 2008 |
Long-term results from a randomized phase II trial of standard-versus higher-dose imatinib mesylate for patients with unresectable or metastatic gastrointestinal stromal tumors … CD Blanke, GD Demetri, M Von Mehren, MC Heinrich, B Eisenberg, ... Journal of clinical oncology 26 (4), 620-625, 2008 | 1339 | 2008 |
PDGFRA Mutations in Gastrointestinal Stromal Tumors: Frequency, Spectrum and In Vitro Sensitivity to Imatinib CL Corless, A Schroeder, D Griffith, A Town, L McGreevey, P Harrell, ... Journal of clinical oncology 23 (23), 5357-5364, 2005 | 1138 | 2005 |
SU11248 is a novel FLT3 tyrosine kinase inhibitor with potent activity in vitro and in vivo AM O'Farrell, TJ Abrams, HA Yuen, TJ Ngai, SG Louie, KWH Yee, ... Blood, The Journal of the American Society of Hematology 101 (9), 3597-3605, 2003 | 1073 | 2003 |
Molecular correlates of imatinib resistance in gastrointestinal stromal tumors MC Heinrich, CL Corless, CD Blanke, GD Demetri, H Joensuu, ... Journal of clinical oncology 24 (29), 4764-4774, 2006 | 1040 | 2006 |
Gastrointestinal stromal tumours: origin and molecular oncology CL Corless, CM Barnett, MC Heinrich Nature Reviews Cancer 11 (12), 865-878, 2011 | 993 | 2011 |
Primary and secondary kinase genotypes correlate with the biological and clinical activity of sunitinib in imatinib-resistant gastrointestinal stromal tumor MC Heinrich, RG Maki, CL Corless, CR Antonescu, A Harlow, D Griffith, ... Journal of clinical oncology 26 (33), 5352-5359, 2008 | 988 | 2008 |
Clinical management of gastrointestinal stromal tumors: before and after STI-571 RP Dematteo, MC Heinrich, ER Wa'el M, G Demetri Human pathology 33 (5), 466-477, 2002 | 916 | 2002 |
Inhibition of KIT tyrosine kinase activity: a novel molecular approach to the treatment of KIT-positive malignancies MC Heinrich, CD Blanke, BJ Druker, CL Corless Journal of clinical oncology 20 (6), 1692-1703, 2002 | 912 | 2002 |
The novel marker, DOG1, is expressed ubiquitously in gastrointestinal stromal tumors irrespective of KIT or PDGFRA mutation status RB West, CL Corless, X Chen, BP Rubin, S Subramanian, K Montgomery, ... The American journal of pathology 165 (1), 107-113, 2004 | 895 | 2004 |
Gastrointestinal stromal tumour BP Rubin, MC Heinrich, CL Corless The Lancet 369 (9574), 1731-1741, 2007 | 861 | 2007 |
KIT Gene Mutations and Copy Number in Melanoma Subtypes C Beadling, E Jacobson-Dunlop, FS Hodi, C Le, A Warrick, J Patterson, ... Clinical Cancer Research 14 (21), 6821-6828, 2008 | 798 | 2008 |
Correlation of kinase genotype and clinical outcome in the North American Intergroup Phase III Trial of imatinib mesylate for treatment of advanced gastrointestinal stromal … MC Heinrich, K Owzar, CL Corless, D Hollis, EC Borden, CDM Fletcher, ... Journal of clinical oncology 26 (33), 5360-5367, 2008 | 772 | 2008 |