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Liz o donovan
Liz o donovan
LMB, MRC Cambridge
Подтвержден адрес электронной почты в домене mrc-lmb.cam.ac.uk
Название
Процитировано
Процитировано
Год
Delivery of therapeutic oligonucleotides with cell penetrating peptides
P Boisguérin, S Deshayes, MJ Gait, L O'Donovan, C Godfrey, CA Betts, ...
Advanced drug delivery reviews 87, 52-67, 2015
2812015
A chemical view of oligonucleotides for exon skipping and related drug applications
P Järver, L O'Donovan, MJ Gait
Nucleic Acid Therapeutics 24 (1), 37-47, 2014
1732014
How much dystrophin is enough: the physiological consequences of different levels of dystrophin in the mdx mouse
C Godfrey, S Muses, G McClorey, KE Wells, T Coursindel, RL Terry, ...
Human molecular genetics 24 (15), 4225-4237, 2015
1482015
Self-assembly into nanoparticles is essential for receptor mediated uptake of therapeutic antisense oligonucleotides
K Ezzat, Y Aoki, T Koo, G McClorey, L Benner, A Coenen-Stass, ...
Nano letters 15 (7), 4364-4373, 2015
1152015
Development and application of an ultrasensitive hybridization-based ELISA method for the determination of peptide-conjugated phosphorodiamidate morpholino oligonucleotides
U Burki, J Keane, A Blain, L O'Donovan, MJ Gait, SH Laval, V Straub
Nucleic acid therapeutics 25 (5), 275-284, 2015
592015
Comprehensive RNA-sequencing analysis in serum and muscle reveals novel small RNA signatures with biomarker potential for DMD
AML Coenen-Stass, H Sork, S Gatto, C Godfrey, A Bhomra, K Krjutškov, ...
Molecular Therapy-Nucleic Acids 13, 1-15, 2018
502018
The influence of the aziridinyl substituent of benzimidazoles and benzimidazolequinones on toxicity towards normal and Fanconi anaemia cells
K Fahey, L O'Donovan, M Carr, MP Carty, F Aldabbagh
European journal of medicinal chemistry 45 (5), 1873-1879, 2010
392010
First synthesis of an aziridinyl fused pyrrolo [1, 2-a] benzimidazole and toxicity evaluation towards normal and breast cancer cell lines
S Bonham, L O'Donovan, MP Carty, F Aldabbagh
Organic & Biomolecular Chemistry 9 (19), 6700-6706, 2011
252011
Synthesis of dimethyl substituted benzimidazoles containing cyclopropane fused onto five to eight membered [1, 2-a] alicyclic rings and influence of methyl group substituents …
S Hehir, L O'Donovan, MP Carty, F Aldabbagh
Tetrahedron 64 (19), 4196-4203, 2008
242008
Parallel synthesis of cell-penetrating peptide conjugates of PMO toward exon skipping enhancement in Duchenne muscular dystrophy
L O'Donovan, I Okamoto, AA Arzumanov, DL Williams, P Deuss, MJ Gait
Nucleic acid therapeutics 25 (1), 1-10, 2015
232015
Peptide-conjugated phosphodiamidate oligomer-mediated exon skipping has benefits for cardiac function in mdx and Cmah-/-mdx mouse models of Duchenne …
AM Blain, E Greally, G McClorey, R Manzano, CA Betts, C Godfrey, ...
PLoS One 13 (6), e0198897, 2018
222018
Cmah-dystrophin deficient mdx mice display an accelerated cardiac phenotype that is improved following peptide-PMO exon skipping treatment
CA Betts, G McClorey, R Healicon, SM Hammond, R Manzano, S Muses, ...
Human Molecular Genetics 28 (3), 396-406, 2019
182019
First synthesis of N-[(aziridin-2-yl) methyl] benzimidazolequinone and analysis of toxicity towards normal and Fanconi anemia cells
L O’Donovan, MP Carty, F Aldabbagh
Chemical communications, 5592-5594, 2008
172008
A photocleavable linker for the chemoselective functionalization of biomaterials
L O'Donovan, A Paul
Journal of Materials Chemistry 22 (41), 21878-21884, 2012
122012
A hydrazide-anchored dendron scaffold for chemoselective ligation strategies
L O'Donovan, A Paul
Organic & Biomolecular Chemistry 12 (37), 7290-7296, 2014
92014
In vitro assays to assess exon skipping in duchenne muscular dystrophy
P Boisguerin, L O’Donovan, MJ Gait, B Lebleu
Cell-Penetrating Peptides: Methods and Protocols, 317-329, 2015
72015
Modulation of Pro-Inflammatory IL-6 Trans-Signaling Axis by Splice Switching Oligonucleotides as a Therapeutic Modality in Inflammation
D Gupta, S Orehek, J Turunen, L O’Donovan, MJ Gait, S El-Andaloussi, ...
Cells 12 (18), 2285, 2023
42023
Cell-penetrating peptide conjugates and methods of their use
M Wood, R Manzano, C Godfrey, G McClorey, R Raz, M Gait, ...
US Patent App. 18/277,013, 2024
2024
Cell-penetrating peptides
M Wood, R Manzano, C Godfrey, G McClorey, R Raz, M Gait, ...
US Patent App. 17/266,939, 2021
2021
Cell-penetrating peptides
M Wood, S El Andaloussi, G McClorey, R Manzano, MJ Gait, C Godfrey, ...
US Patent App. 17/266,940, 2021
2021
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