| Structural insights into intermediate steps in the Sir2 deacetylation reaction WF Hawse, KG Hoff, DG Fatkins, A Daines, OV Zubkova, VL Schramm, ... Structure 16 (9), 1368-1377, 2008 | 143 | 2008 |
| Synthesis of a Targeted Library of Heparan Sulfate Hexa‐to Dodecasaccharides as Inhibitors of β‐Secretase: Potential Therapeutics for Alzheimer’s Disease R Schwörer, OV Zubkova, JE Turnbull, PC Tyler Chemistry–A European Journal 19 (21), 6817-6823, 2013 | 115 | 2013 |
| Energetic Mapping of Transition State Analogue Interactions with Human and Plasmodium falciparum Purine Nucleoside Phosphorylases*♦ A Lewandowicz, EAT Ringia, LM Ting, K Kim, PC Tyler, GB Evans, ... Journal of Biological Chemistry 280 (34), 30320-30328, 2005 | 70 | 2005 |
| Inhibitors of ADP-ribosylating bacterial toxins based on oxacarbenium ion character at their transition states GC Zhou, SL Parikh, PC Tyler, GB Evans, RH Furneaux, OV Zubkova, ... Journal of the American chemical society 126 (18), 5690-5698, 2004 | 63 | 2004 |
| Shotgun ion mobility mass spectrometry sequencing of heparan sulfate saccharides RL Miller, SE Guimond, R Schwörer, OV Zubkova, PC Tyler, Y Xu, J Liu, ... Nature communications 11 (1), 1481, 2020 | 59 | 2020 |
| Single‐entity heparan sulfate glycomimetic clusters for therapeutic applications PC Tyler, SE Guimond, JE Turnbull, OV Zubkova Angewandte Chemie International Edition 54 (9), 2718-2723, 2015 | 45 | 2015 |
| Dendrimer heparan sulfate glycomimetics: potent heparanase inhibitors for anticancer therapy OV Zubkova, YA Ahmed, SE Guimond, SL Noble, JH Miller, ... ACS Chemical Biology 13 (12), 3236-3242, 2018 | 37 | 2018 |
| 5h-pyrrolo [3, 2-D] pyrimidine inhibitors of nucleoside phosphorylases and nucleosidases GB Evans, RH Furneaux, DH Lenz, VL Schramm, PC Tyler, OV Zubkova US Patent 7,553,839, 2009 | 34 | 2009 |
| Composition, sequencing and ion mobility mass spectrometry of heparan sulfate-like octasaccharide isomers differing in glucuronic and iduronic acid content RL Miller, W Wei, R Schwörer, OV Zubkova, PC Tyler, JE Turnbull, ... European Journal of Mass Spectrometry 21 (3), 245-254, 2015 | 27 | 2015 |
| Inhibitors of nucleoside phosphorylases and nucleosidases GB Evans, RH Furneaux, VL Schramm, PC Tyler, SPH Mee, OV Zubkova US Patent App. 11/920,097, 2009 | 26 | 2009 |
| Fused pyrimidines as inhibitors of nucleoside phosphorylases and nucleosidases GB Evans, RH Furneaux, DH Lenz, VL Schramm, PC Tyler, OV Zubkova US Patent 8,173,662, 2012 | 22 | 2012 |
| Syntheses of novel azasugar-containing mimics of heparan sulfate fragments as potential heparanase inhibitors KA Allen, RL Brown, G Norris, PC Tyler, DK Watt, OV Zubkova Carbohydrate research 345 (13), 1831-1841, 2010 | 14 | 2010 |
| Reducing the toxicity of designer aminoglycosides as nonsense mutation readthrough agents for therapeutic targets M Popadynec, A Baradaran-Heravi, B Alford, SA Cameron, K Clinch, ... ACS Medicinal Chemistry Letters 12 (9), 1486-1492, 2021 | 12 | 2021 |
| Synthesis of novel glycolipid mimetics of heparan sulfate and their application in colorectal cancer treatment in a mouse model S Spijkers‐Shaw, K Campbell, NJ Shields, JH Miller, PM Rendle, W Jiao, ... Chemistry–An Asian Journal 17 (12), e202200228, 2022 | 10 | 2022 |
| Heparanase inhibition as a systemic approach to protect the endothelial glycocalyx and prevent microvascular complications in diabetes M Gamez, HE Elhegni, S Fawaz, KH Ho, NW Campbell, DA Copland, ... Cardiovascular Diabetology 23 (1), 1-17, 2024 | 7 | 2024 |
| The novel HS-mimetic, Tet-29, regulates immune cell trafficking across barriers of the CNS during inflammation T Peck, C Davis, G Lenihan-Geels, M Griffiths, S Spijkers-Shaw, ... Journal of Neuroinflammation 20 (1), 251, 2023 | 5 | 2023 |
| A synthetic heparan sulphate mimetic for enhancing BMP-2-mediated osteogenesis and bone regeneration RA Smith, X Lu, T Tan, X Luo, BQ Le, OV Zubkova, S Cool, V Nurcombe Cytotherapy 22 (5), S32, 2020 | 4 | 2020 |
| Thin-layer chromatography and polyacrylamide gel electrophoresis-based assays for sialyltransferases using tetramethylrhodamine-labeled acceptors U Hubl, GC Slim, OV Zubkova Analytical Biochemistry 285 (1), 92-99, 2000 | 4 | 2000 |
| Enhancing BMP-2-mediated osteogenesis with a synthetic heparan sulfate mimetic RAA Smith, X Luo, X Lu, TC Tan, BQ Le, OV Zubkova, PC Tyler, ... Biomaterials Advances 155, 213671, 2023 | 3 | 2023 |
| Recovery of post-stroke spatial memory and Thalamocortical connectivity following novel Glycomimetic and rhBDNF treatment J Houlton, OV Zubkova, AN Clarkson International journal of molecular sciences 23 (9), 4817, 2022 | 3 | 2022 |
