| Alternative pre-mRNA splicing: the logic of combinatorial control CWJ Smith, J Valcárcel Trends in biochemical sciences 25 (8), 381-388, 2000 | 1211 | 2000 |
| Alternative splicing and genome complexity D Brett, H Pospisil, J Valcárcel, J Reich, P Bork Nature genetics 30 (1), 29-30, 2002 | 677 | 2002 |
| Distinct binding specificities and functions of higher eukaryotic polypyrimidine tract-binding proteins R Singh, J Valcarcel, MR Green Science 268 (5214), 1173-1176, 1995 | 673 | 1995 |
| Synonymous mutations frequently act as driver mutations in human cancers F Supek, B Miñana, J Valcárcel, T Gabaldón, B Lehner Cell 156 (6), 1324-1335, 2014 | 629 | 2014 |
| Roles and mechanisms of alternative splicing in cancer—implications for care SC Bonnal, I López-Oreja, J Valcárcel Nature reviews Clinical oncology 17 (8), 457-474, 2020 | 587 | 2020 |
| Nucleosome positioning as a determinant of exon recognition H Tilgner, C Nikolaou, S Althammer, M Sammeth, M Beato, J Valcárcel, ... Nature structural & molecular biology 16 (9), 996-1001, 2009 | 549 | 2009 |
| RNA-binding proteins in human genetic disease F Gebauer, T Schwarzl, J Valcárcel, MW Hentze Nature Reviews Genetics 22 (3), 185-198, 2021 | 536 | 2021 |
| The protein Sex-lethal antagonizes the splicing factor U2AF to regulate alternative splicing of transformer pre-mRNA J Valcárcel, R Singh, PD Zamore, MR Green Nature 362 (6416), 171-175, 1993 | 469 | 1993 |
| The spliceosome as a target of novel antitumour drugs S Bonnal, L Vigevani, J Valcárcel Nature reviews Drug discovery 11 (11), 847-859, 2012 | 467 | 2012 |
| Regulation of Fas alternative splicing by antagonistic effects of TIA-1 and PTB on exon definition JM Izquierdo, N Majós, S Bonnal, C Martínez, R Castelo, R Guigó, ... Molecular cell 19 (4), 475-484, 2005 | 444 | 2005 |
| Optimization of oligonucleotide-based DNA microarrays A Relógio, C Schwager, A Richter, W Ansorge, J Valcárcel Nucleic acids research 30 (11), e51-e51, 2002 | 410 | 2002 |
| Interaction of U2AF65 RS region with pre-mRNA of branch point and promotion base pairing with U2 snRNA J Valcárcel, RK Gaur, R Singh, MR Green Science 273 (5282), 1706-1709, 1996 | 388 | 1996 |
| Inhibition of msl-2 splicing by Sex-lethal reveals interaction between U2AF35 and the 3′ splice site AG L Merendino, S Guth, D Bilbao, C Martínez, J Valcárcel Nature 402 (6763), 838-841, 1999 | 374 | 1999 |
| RBM5, 6, and 10 differentially regulate NUMB alternative splicing to control cancer cell proliferation EG Bechara, E Sebestyén, I Bernardis, E Eyras, J Valcárcel Molecular cell 52 (5), 720-733, 2013 | 366 | 2013 |
| U2AF65 recruits a novel human DEAD box protein required for the U2 snRNP-branchpoint interaction. J Fleckner, M Zhang, J Valcarcel, MR Green Genes & development 11 (14), 1864-1872, 1997 | 356 | 1997 |
| The SR protein family: pleiotropic functions in pre-mRNA splicing J Valcárcel, MR Green Trends in biochemical sciences 21 (8), 296-301, 1996 | 351 | 1996 |
| The apoptosis-promoting factor TIA-1 is a regulator of alternative pre-mRNA splicing P Förch, O Puig, N Kedersha, C Martínez, S Granneman, B Séraphin, ... Molecular cell 6 (5), 1089-1098, 2000 | 340 | 2000 |
| The spliceosome: the ultimate RNA chaperone and sculptor P Papasaikas, J Valcárcel Trends in biochemical sciences 41 (1), 33-45, 2016 | 291 | 2016 |
| Large-scale analysis of genome and transcriptome alterations in multiple tumors unveils novel cancer-relevant splicing networks E Sebestyén, B Singh, B Miñana, A Pagès, F Mateo, MA Pujana, ... Genome research 26 (6), 732-744, 2016 | 290 | 2016 |
| Reduced fidelity of branch point recognition and alternative splicing induced by the anti-tumor drug spliceostatin A A Corrionero, B Miñana, J Valcárcel Genes & development 25 (5), 445-459, 2011 | 287 | 2011 |
