| High-throughput discovery of novel developmental phenotypes ME Dickinson, AM Flenniken, X Ji, L Teboul, MD Wong, JK White, ... Nature 537 (7621), 508-514, 2016 | 1137 | 2016 |
| Cardioprotection and lifespan extension by the natural polyamine spermidine T Eisenberg, M Abdellatif, S Schroeder, U Primessnig, S Stekovic, T Pendl, ... Nature medicine 22 (12), 1428-1438, 2016 | 1036 | 2016 |
| A humanized version of Foxp2 affects cortico-basal ganglia circuits in mice W Enard, S Gehre, K Hammerschmidt, SM Hölter, T Blass, M Somel, ... Cell 137 (5), 961-971, 2009 | 703 | 2009 |
| Aberrant methylation of t RNA s links cellular stress to neuro‐developmental disorders S Blanco, S Dietmann, JV Flores, S Hussain, C Kutter, P Humphreys, ... The EMBO journal 33 (18), 2020-2039, 2014 | 566 | 2014 |
| A comparative phenotypic and genomic analysis of C57BL/6J and C57BL/6N mouse strains MM Simon, S Greenaway, JK White, H Fuchs, V Gailus-Durner, S Wells, ... Genome biology 14, 1-22, 2013 | 544 | 2013 |
| Post-stroke inhibition of induced NADPH oxidase type 4 prevents oxidative stress and neurodegeneration C Kleinschnitz, H Grund, K Wingler, ME Armitage, E Jones, M Mittal, ... PLoS biology 8 (9), e1000479, 2010 | 510 | 2010 |
| Rapamycin extends murine lifespan but has limited effects on aging F Neff, D Flores-Dominguez, DP Ryan, M Horsch, S Schröder, T Adler, ... The Journal of clinical investigation 123 (8), 3272-3291, 2013 | 406 | 2013 |
| Sum1 and Hst1 repress middle sporulation‐specific gene expression during mitosis in Saccharomyces cerevisiae J Xie, M Pierce, V Gailus‐Durner, M Wagner, E Winter, AK Vershon The EMBO journal, 1999 | 271 | 1999 |
| Prevalence of sexual dimorphism in mammalian phenotypic traits NA Karp, J Mason, AL Beaudet, Y Benjamini, L Bower, RE Braun, ... Nature communications 8 (1), 15475, 2017 | 253 | 2017 |
| Disease model discovery from 3,328 gene knockouts by The International Mouse Phenotyping Consortium TF Meehan, N Conte, DB West, JO Jacobsen, J Mason, J Warren, ... Nature genetics 49 (8), 1231-1238, 2017 | 240 | 2017 |
| Expression pattern of G protein-coupled receptor 30 in LacZ reporter mice J Isensee, L Meoli, V Zazzu, C Nabzdyk, H Witt, D Soewarto, K Effertz, ... Endocrinology 150 (4), 1722-1730, 2009 | 220 | 2009 |
| Introducing the German Mouse Clinic: open access platform for standardized phenotyping V Gailus-Durner, H Fuchs, L Becker, I Bolle, M Brielmeier, ... Nature methods 2 (6), 403-404, 2005 | 220 | 2005 |
| Neuronal 3′, 3, 5-triiodothyronine (T3) uptake and behavioral phenotype of mice deficient in Mct8, the neuronal T3 transporter mutated in Allan–Herndon–Dudley syndrome EK Wirth, S Roth, C Blechschmidt, SM Hölter, L Becker, I Racz, A Zimmer, ... Journal of Neuroscience 29 (30), 9439-9449, 2009 | 211 | 2009 |
| Calcitonin controls bone formation by inhibiting the release of sphingosine 1-phosphate from osteoclasts J Keller, P Catala-Lehnen, AK Huebner, A Jeschke, T Heckt, A Lueth, ... Nature communications 5 (1), 5215, 2014 | 207 | 2014 |
| Chemical hybridization of glucagon and thyroid hormone optimizes therapeutic impact for metabolic disease B Finan, C Clemmensen, Z Zhu, K Stemmer, K Gauthier, L Müller, ... Cell 167 (3), 843-857. e14, 2016 | 193 | 2016 |
| Mouse phenotyping H Fuchs, V Gailus-Durner, T Adler, JA Aguilar-Pimentel, L Becker, ... Methods 53 (2), 120-135, 2011 | 165 | 2011 |
| Mouse large-scale phenotyping initiatives: Overview of the European mouse disease clinic (EUMODIC) and of the Wellcome Trust Sanger Institute Mouse Genetics Project A Ayadi, MC Birling, J Bottomley, J Bussell, H Fuchs, M Fray, ... Mammalian Genome 23, 600-610, 2012 | 159 | 2012 |
| Creatine improves health and survival of mice A Bender, J Beckers, I Schneider, SM Hölter, T Haack, T Ruthsatz, ... Neurobiology of Aging 29 (9), 1404-1411, 2008 | 149 | 2008 |
| Analysis of mammalian gene function through broad-based phenotypic screens across a consortium of mouse clinics M Hrabě de Angelis, G Nicholson, M Selloum, JK White, H Morgan, ... Nature genetics 47 (9), 969-978, 2015 | 148 | 2015 |
| Spinal poly-GA inclusions in a C9orf72 mouse model trigger motor deficits and inflammation without neuron loss MH Schludi, L Becker, L Garrett, TF Gendron, Q Zhou, F Schreiber, ... Acta neuropathologica 134, 241-254, 2017 | 137 | 2017 |