Общедоступные статьи - Tom L BlundellПодробнее...
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10 статей недоступны нигде
Tumor risks and genotype–phenotype–proteotype analysis in 358 patients with germline mutations in SDHB and SDHD
CJ Ricketts, JR Forman, E Rattenberry, N Bradshaw, F Lalloo, L Izatt, ...
Human mutation 31 (1), 41-51, 2010
Финансирование: Cancer Research UK
Protein–protein interactions as druggable targets: recent technological advances
AP Higueruelo, H Jubb, TL Blundell
Current opinion in pharmacology 13 (5), 791-796, 2013
Финансирование: UK Biotechnology and Biological Sciences Research Council
Identifying interactions that determine fragment binding at protein hotspots
CJ Radoux, TSG Olsson, WR Pitt, CR Groom, TL Blundell
Journal of medicinal chemistry 59 (9), 4314-4325, 2016
Финансирование: UK Biotechnology and Biological Sciences Research Council, UK Medical …
Structural bioinformatics mutation analysis reveals genotype–phenotype correlations in von Hippel‐Lindau disease and suggests molecular mechanisms of tumorigenesis
JR Forman, CL Worth, GRJ Bickerton, TG Eisen, TL Blundell
Proteins: Structure, Function, and Bioinformatics 77 (1), 84-96, 2009
Финансирование: Cancer Research UK
Structural biology of multicomponent assemblies in DNA double-strand-break repair through non-homologous end joining
AK Chaplin, TL Blundell
Current opinion in structural biology 61, 9-16, 2020
Финансирование: Wellcome Trust
Multicomponent assemblies in DNA-double-strand break repair by NHEJ
A Hnízda, TL Blundell
Current opinion in structural biology 55, 154-160, 2019
Финансирование: Wellcome Trust
Design and Structural Analysis of Aromatic Inhibitors of Type II Dehydroquinase from Mycobacterium tuberculosis
NI Howard, MVB Dias, F Peyrot, L Chen, MF Schmidt, TL Blundell, C Abell
ChemMedChem 10 (1), 116-133, 2015
Финансирование: Bill & Melinda Gates Foundation, UK Engineering and Physical Sciences …
The first resolution revolution in protein structure analysis: X-ray diffraction of polypeptide conformations and globular protein folds in 1950s and 1960s
TL Blundell
Progress in Biophysics and Molecular Biology 167, 32-40, 2021
Финансирование: Bill & Melinda Gates Foundation, Wellcome Trust
The Genome3D Consortium for structural annotations of selected model organisms
VP Waman, TL Blundell, DWA Buchan, J Gough, D Jones, L Kelley, ...
Protein Structure Prediction, 27-67, 2020
Финансирование: UK Biotechnology and Biological Sciences Research Council
Structure-guided fragment-based drug discovery at the synchrotron
SE Thomas, P Collins, RH James, V Mendes, S Charoensutthivarakul, ...
Philosophical Transactions: Mathematical, Physical and Engineering Sciences …, 2019
Финансирование: Bill & Melinda Gates Foundation
184 статьи доступны в некоторых источниках
pkCSM: predicting small-molecule pharmacokinetic and toxicity properties using graph-based signatures
DEV Pires, TL Blundell, DB Ascher
Journal of medicinal chemistry 58 (9), 4066-4072, 2015
Финансирование: National Health and Medical Research Council, Australia, UK Biotechnology …
mCSM: predicting the effects of mutations in proteins using graph-based signatures
DEV Pires, DB Ascher, TL Blundell
Bioinformatics 30 (3), 335-342, 2014
Финансирование: Wellcome Trust
DUET: a server for predicting effects of mutations on protein stability using an integrated computational approach
DEV Pires, DB Ascher, TL Blundell
Nucleic acids research 42 (W1), W314-W319, 2014
Финансирование: National Health and Medical Research Council, Australia, Wellcome Trust
Arpeggio: a web server for calculating and visualising interatomic interactions in protein structures
HC Jubb, AP Higueruelo, B Ochoa-Montaño, WR Pitt, DB Ascher, ...
Journal of molecular biology 429 (3), 365-371, 2017
Финансирование: Bill & Melinda Gates Foundation, National Health and Medical Research …
SDM: a server for predicting effects of mutations on protein stability
AP Pandurangan, B Ochoa-Montano, DB Ascher, TL Blundell
Nucleic acids research 45 (W1), W229-W235, 2017
Финансирование: Bill & Melinda Gates Foundation, National Health and Medical Research …
PAXX, a paralog of XRCC4 and XLF, interacts with Ku to promote DNA double-strand break repair
T Ochi, AN Blackford, J Coates, S Jhujh, S Mehmood, N Tamura, ...
Science 347 (6218), 185-188, 2015
Финансирование: Cancer Research UK, Wellcome Trust, European Commission
Crystal structure of DNA-PKcs reveals a large open-ring cradle comprised of HEAT repeats
BL Sibanda, DY Chirgadze, TL Blundell
Nature 463 (7277), 118-121, 2010
Финансирование: Cancer Research UK
Whole-genome sequencing coupled to imputation discovers genetic signals for anthropometric traits
I Tachmazidou, D Süveges, JL Min, GRS Ritchie, J Steinberg, K Walter, ...
The American Journal of Human Genetics 100 (6), 865-884, 2017
Финансирование: Bill & Melinda Gates Foundation, US National Institutes of Health, Academy …
DNA-PKcs structure suggests an allosteric mechanism modulating DNA double-strand break repair
BL Sibanda, DY Chirgadze, DB Ascher, TL Blundell
Science 355 (6324), 520-524, 2017
Финансирование: UK Biotechnology and Biological Sciences Research Council, Wellcome Trust
Mutations at protein-protein interfaces: Small changes over big surfaces have large impacts on human health
HC Jubb, AP Pandurangan, MA Turner, B Ochoa-Montaño, TL Blundell, ...
Progress in biophysics and molecular biology 128, 3-13, 2017
Финансирование: Bill & Melinda Gates Foundation, National Health and Medical Research …
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