A major inducer of anticarcinogenic protective enzymes from broccoli: isolation and elucidation of structure. Y Zhang, P Talalay, CG Cho, GH Posner Proceedings of the national academy of sciences 89 (6), 2399-2403, 1992 | 2240 | 1992 |
Broccoli sprouts: an exceptionally rich source of inducers of enzymes that protect against chemical carcinogens JW Fahey, Y Zhang, P Talalay Proceedings of the National Academy of Sciences 94 (19), 10367-10372, 1997 | 1852 | 1997 |
Anticarcinogenic activities of sulforaphane and structurally related synthetic norbornyl isothiocyanates. Y Zhang, TW Kensler, CG Cho, GH Posner, P Talalay Proceedings of the National Academy of Sciences 91 (8), 3147-3150, 1994 | 1016 | 1994 |
Anticarcinogenic activities of organic isothiocyanates: chemistry and mechanisms Y Zhang, P Talalay Cancer research 54 (7_Supplement), 1976s-1981s, 1994 | 807 | 1994 |
Chemoprotection against cancer by phase 2 enzyme induction P Talalay, JW Fahey, WD Holtzclaw, T Prestera, Y Zhang Toxicology letters 82, 173-179, 1995 | 613 | 1995 |
Chemical and molecular regulation of enzymes that detoxify carcinogens. T Prestera, WD Holtzclaw, Y Zhang, P Talalay Proceedings of the National Academy of Sciences 90 (7), 2965-2969, 1993 | 559 | 1993 |
Quantitative determination of dithiocarbamates in human plasma, serum, erythrocytes and urine: pharmacokinetics of broccoli sprout isothiocyanates in humans L Ye, AT Dinkova-Kostova, KL Wade, Y Zhang, TA Shapiro, P Talalay Clinica chimica acta 316 (1-2), 43-53, 2002 | 450 | 2002 |
Breast cancer risk in premenopausal women is inversely associated with consumption of broccoli, a source of isothiocyanates, but is not modified by GST genotype CB Ambrosone, SE McCann, JL Freudenheim, ... Journal of Nutrition 134, 1134-1138, 2004 | 422 | 2004 |
Cancer-preventive isothiocyanates: measurement of human exposure and mechanism of action Y Zhang Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 555 (1 …, 2004 | 420 | 2004 |
The electrophile counterattack response: protection against neoplasia and toxicity T Prestera, Y Zhang, SR Spencer, CA Wilczak, P Talalay Advances in enzyme regulation 33, 281-296, 1993 | 350 | 1993 |
Isothiocyanates as substrates for human glutathione transferases: structure-activity studies RH Kolm, UH Danielson, Y Zhang, P Talalay, B Mannervik Biochemical Journal 311 (2), 453-459, 1995 | 318 | 1995 |
A strategy for cancer prevention: stimulation of the Nrf2-ARE signaling pathway Y Zhang, GB Gordon Molecular cancer therapeutics 3 (7), 885-893, 2004 | 310 | 2004 |
Cruciferous vegetables, genetic polymorphisms in glutathione S-transferases M1 and T1, and prostate cancer risk MA Joseph, KB Moysich, JL Freudenheim, PG Shields, ED Bowman, ... Nutrition and Cancer 50, 206-213, 2004 | 308 | 2004 |
Human prx1 gene is a target of Nrf2 and is up-regulated by hypoxia/reoxygenation: Implication to tumor biology YJ Kim, JY Ahn, P Liang, C Ip, Y Zhang, YM Park Cancer Research 67, 546-554, 2007 | 306 | 2007 |
Mechanism of differential potencies of isothiocyanates as inducers of anticarcinogenic Phase 2 enzymes Y Zhang, P Talalay Cancer research 58 (20), 4632-4639, 1998 | 299 | 1998 |
Allyl isothiocyanate as a cancer chemopreventive phytochemical Y Zhang Molecular nutrition & food research 54 (1), 127-135, 2010 | 296 | 2010 |
Role of glutathione in the accumulation of anticarcinogenic isothiocyanates and their glutathione conjugates by murine hepatoma cells Y Zhang Carcinogenesis 21 (6), 1175-1182, 2000 | 288 | 2000 |
Selected isothiocyanates rapidly induce growth inhibition of cancer cells Y Zhang, L Tang, V Gonzalez Molecular cancer therapeutics 2 (10), 1045-1052, 2003 | 286 | 2003 |
Discovery and development of sulforaphane as a cancer chemopreventive phytochemical1 Y Zhang, L Tang Acta Pharmacologica Sinica 28 (9), 1343-1354, 2007 | 272 | 2007 |
Quantitative determination of isothiocyanates, dithiocarbamates, carbon disulfide, and related thiocarbonyl compounds by cyclocondensation with 1, 2-benzenedithiol Y Zhang, KL Wade, T Prestera, P Talalay Analytical biochemistry 239 (2), 160-167, 1996 | 259 | 1996 |