B70 antigen is a second ligand for CTLA-4 and CD28 M Azuma, D Ito, H Yagita, K Okumura, JH Phillips, LL Lanier, C Somoza Nature 366 (6450), 76-79, 1993 | 1318 | 1993 |
Expression of programmed death 1 ligands by murine T cells and APC T Yamazaki, H Akiba, H Iwai, H Matsuda, M Aoki, Y Tanno, T Shin, ... The Journal of Immunology 169 (10), 5538-5545, 2002 | 1314 | 2002 |
Programmed cell death 1 forms negative costimulatory microclusters that directly inhibit T cell receptor signaling by recruiting phosphatase SHP2 T Yokosuka, M Takamatsu, W Kobayashi-Imanishi, A Hashimoto-Tane, ... Journal of Experimental Medicine 209 (6), 1201-1217, 2012 | 1283 | 2012 |
Clinical significance and therapeutic potential of the programmed death-1 ligand/programmed death-1 pathway in human pancreatic cancer T Nomi, M Sho, T Akahori, K Hamada, A Kubo, H Kanehiro, S Nakamura, ... Clinical cancer research 13 (7), 2151-2157, 2007 | 1238 | 2007 |
Clinical significance of programmed death-1 ligand-1 and programmed death-1 ligand-2 expression in human esophageal cancer Y Ohigashi, M Sho, Y Yamada, Y Tsurui, K Hamada, N Ikeda, T Mizuno, ... Clinical cancer research 11 (8), 2947-2953, 2005 | 1185 | 2005 |
The programmed death-1 (PD-1) pathway regulates autoimmune diabetes in nonobese diabetic (NOD) mice MJI Ansari, AD Salama, T Chitnis, RN Smith, H Yagita, H Akiba, ... The Journal of experimental medicine 198 (1), 63-69, 2003 | 1018 | 2003 |
Plasmacytoid dendritic cells from mouse tumor-draining lymph nodes directly activate mature Tregs via indoleamine 2, 3-dioxygenase MD Sharma, B Baban, P Chandler, DY Hou, N Singh, H Yagita, M Azuma, ... The Journal of clinical investigation 117 (9), 2570-2582, 2007 | 1008 | 2007 |
B7-H1 expression on non-small cell lung cancer cells and its relationship with tumor-infiltrating lymphocytes and their PD-1 expression J Konishi, K Yamazaki, M Azuma, I Kinoshita, H Dosaka-Akita, ... Clinical cancer research 10 (15), 5094-5100, 2004 | 982 | 2004 |
Interactions between PD-1 and PD-L1 promote tolerance by blocking the TCR–induced stop signal BT Fife, KE Pauken, TN Eagar, T Obu, J Wu, Q Tang, M Azuma, ... Nature immunology 10 (11), 1185-1192, 2009 | 887 | 2009 |
The tissue distribution of the B7-2 costimulator in mice: abundant expression on dendritic cells in situ and during maturation in vitro. K Inaba, M Witmer-Pack, M Inaba, KS Hathcock, H Sakuta, M Azuma, ... The Journal of experimental medicine 180 (5), 1849-1860, 1994 | 834 | 1994 |
Coexpression of Tim-3 and PD-1 identifies a CD8+ T-cell exhaustion phenotype in mice with disseminated acute myelogenous leukemia Q Zhou, ME Munger, RG Veenstra, BJ Weigel, M Hirashima, DH Munn, ... Blood, The Journal of the American Society of Hematology 117 (17), 4501-4510, 2011 | 762 | 2011 |
Apoptotic signaling through CD95 (Fas/Apo-1) activates an acidic sphingomyelinase. MG Cifone, R De Maria, P Roncaioli, MR Rippo, M Azuma, LL Lanier, ... The Journal of experimental medicine 180 (4), 1547-1552, 1994 | 755 | 1994 |
Critical role of the programmed death-1 (PD-1) pathway in regulation of experimental autoimmune encephalomyelitis AD Salama, T Chitnis, J Imitola, MJI Ansari, H Akiba, F Tushima, M Azuma, ... The Journal of experimental medicine 198 (1), 71-78, 2003 | 687 | 2003 |
CD80 (B7) and CD86 (B70) provide similar costimulatory signals for T cell proliferation, cytokine production, and generation of CTL. LL Lanier, S O'Fallon, C Somoza, JH Phillips, PS Linsley, K Okumura, ... Journal of Immunology (Baltimore, Md.: 1950) 154 (1), 97-105, 1995 | 651 | 1995 |
Overexpression of B7-H1 (PD-L1) significantly associates with tumor grade and postoperative prognosis in human urothelial cancers J Nakanishi, Y Wada, K Matsumoto, M Azuma, K Kikuchi, S Ueda Cancer Immunology, Immunotherapy 56, 1173-1182, 2007 | 638 | 2007 |
A critical role for the programmed death ligand 1 in fetomaternal tolerance I Guleria, A Khosroshahi, MJ Ansari, A Habicht, M Azuma, H Yagita, ... The Journal of experimental medicine 202 (2), 231-237, 2005 | 526 | 2005 |
Tim-3 mediates phagocytosis of apoptotic cells and cross-presentation M Nakayama, H Akiba, K Takeda, Y Kojima, M Hashiguchi, M Azuma, ... Blood, The Journal of the American Society of Hematology 113 (16), 3821-3830, 2009 | 520 | 2009 |
CD28-T lymphocytes. Antigenic and functional properties. M Azuma, JH Phillips, LL Lanier Journal of immunology (Baltimore, Md.: 1950) 150 (4), 1147-1159, 1993 | 494 | 1993 |
CD28 interaction with B7 costimulates primary allogeneic proliferative responses and cytotoxicity mediated by small, resting T lymphocytes. M Azuma, M Cayabyab, D Buck, JH Phillips, LL Lanier The Journal of experimental medicine 175 (2), 353-360, 1992 | 466 | 1992 |
B70/B7-2 is identical to CD86 and is the major functional ligand for CD28 expressed on human dendritic cells. C Caux, B Vanbervliet, C Massacrier, M Azuma, K Okumura, LL Lanier, ... The Journal of experimental medicine 180 (5), 1841-1847, 1994 | 463 | 1994 |