Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018 L Galluzzi, I Vitale, SA Aaronson, JM Abrams, D Adam, P Agostinis, ... Cell Death & Differentiation 25 (3), 486-541, 2018 | 6064 | 2018 |
Ferroptosis: a regulated cell death nexus linking metabolism, redox biology, and disease BR Stockwell, JPF Angeli, H Bayir, AI Bush, M Conrad, SJ Dixon, S Fulda, ... Cell 171 (2), 273-285, 2017 | 5489 | 2017 |
Ferroptosis: mechanisms, biology and role in disease X Jiang, BR Stockwell, M Conrad Nature reviews Molecular cell biology 22 (4), 266-282, 2021 | 3740 | 2021 |
Inactivation of the ferroptosis regulator Gpx4 triggers acute renal failure in mice JP Friedmann Angeli, M Schneider, B Proneth, YY Tyurina, VA Tyurin, ... Nature cell biology 16 (12), 1180-1191, 2014 | 2968 | 2014 |
ACSL4 dictates ferroptosis sensitivity by shaping cellular lipid composition S Doll, B Proneth, YY Tyurina, E Panzilius, S Kobayashi, I Ingold, M Irmler, ... Nature chemical biology 13 (1), 91-98, 2017 | 2864 | 2017 |
FSP1 is a glutathione-independent ferroptosis suppressor S Doll, FP Freitas, R Shah, M Aldrovandi, MC da Silva, I Ingold, ... Nature 575 (7784), 693-698, 2019 | 2272 | 2019 |
Oxidized arachidonic and adrenic PEs navigate cells to ferroptosis VE Kagan, G Mao, F Qu, JPF Angeli, S Doll, CS Croix, HH Dar, B Liu, ... Nature chemical biology 13 (1), 81-90, 2017 | 2183 | 2017 |
Glutathione peroxidase 4 senses and translates oxidative stress into 12/15-lipoxygenase dependent-and AIF-mediated cell death A Seiler, M Schneider, H Förster, S Roth, EK Wirth, C Culmsee, N Plesnila, ... Cell metabolism 8 (3), 237-248, 2008 | 1400 | 2008 |
Selenium utilization by GPX4 is required to prevent hydroperoxide-induced ferroptosis I Ingold, C Berndt, S Schmitt, S Doll, G Poschmann, K Buday, A Roveri, ... Cell 172 (3), 409-422. e21, 2018 | 1251 | 2018 |
Role of GPX4 in ferroptosis and its pharmacological implication TM Seibt, B Proneth, M Conrad Free Radical Biology and Medicine 133, 144-152, 2019 | 1054 | 2019 |
Ferroptosis at the crossroads of cancer-acquired drug resistance and immune evasion JP Friedmann Angeli, DV Krysko, M Conrad Nature Reviews Cancer 19 (7), 405-414, 2019 | 949 | 2019 |
The metabolic underpinnings of ferroptosis J Zheng, M Conrad Cell metabolism 32 (6), 920-937, 2020 | 866 | 2020 |
On the mechanism of cytoprotection by ferrostatin-1 and liproxstatin-1 and the role of lipid peroxidation in ferroptotic cell death O Zilka, R Shah, B Li, JP Friedmann Angeli, M Griesser, M Conrad, ... ACS central science 3 (3), 232-243, 2017 | 789 | 2017 |
The chemical basis of ferroptosis M Conrad, DA Pratt Nature chemical biology 15 (12), 1137-1147, 2019 | 690 | 2019 |
Regulated necrosis: disease relevance and therapeutic opportunities M Conrad, JPF Angeli, P Vandenabeele, BR Stockwell Nature reviews Drug discovery 15 (5), 348-366, 2016 | 660 | 2016 |
Ultrasmall nanoparticles induce ferroptosis in nutrient-deprived cancer cells and suppress tumour growth SE Kim, L Zhang, K Ma, M Riegman, F Chen, I Ingold, M Conrad, ... Nature nanotechnology 11 (11), 977-985, 2016 | 611 | 2016 |
The oxidative stress-inducible cystine/glutamate antiporter, system x c − : cystine supplier and beyond M Conrad, H Sato Amino acids 42, 231-246, 2012 | 588 | 2012 |
Essential role for mitochondrial thioredoxin reductase in hematopoiesis, heart development, and heart function M Conrad, C Jakupoglu, SG Moreno, S Lippl, A Banjac, M Schneider, ... Molecular and cellular biology 24 (21), 9414-9423, 2004 | 585 | 2004 |
T cell lipid peroxidation induces ferroptosis and prevents immunity to infection M Matsushita, S Freigang, C Schneider, M Conrad, GW Bornkamm, ... Journal of Experimental Medicine 212 (4), 555-568, 2015 | 549 | 2015 |
Nano-targeted induction of dual ferroptotic mechanisms eradicates high-risk neuroblastoma B Hassannia, B Wiernicki, I Ingold, F Qu, S Van Herck, YY Tyurina, ... The Journal of clinical investigation 128 (8), 3341-3355, 2018 | 522 | 2018 |