| A multivariate analysis of 416 patients with glioblastoma multiforme: prognosis, extent of resection, and survival M Lacroix, D Abi-Said, DR Fourney, ZL Gokaslan, W Shi, F DeMonte, ... Journal of neurosurgery 95 (2), 190-198, 2001 | 3746 | 2001 |
| CSF-1R inhibition alters macrophage polarization and blocks glioma progression SM Pyonteck, L Akkari, AJ Schuhmacher, RL Bowman, L Sevenich, ... Nature medicine 19 (10), 1264-1272, 2013 | 2386 | 2013 |
| A brain tumor molecular imaging strategy using a new triple-modality MRI-photoacoustic-Raman nanoparticle MF Kircher, A De La Zerda, JV Jokerst, CL Zavaleta, PJ Kempen, E Mittra, ... Nature medicine 18 (5), 829-834, 2012 | 1213 | 2012 |
| Combined activation of Ras and Akt in neural progenitors induces glioblastoma formation in mice EC Holland, J Celestino, C Dai, L Schaefer, RE Sawaya, GN Fuller Nature genetics 25 (1), 55-57, 2000 | 1151 | 2000 |
| Glioblastoma multiforme: the terminator EC Holland Proceedings of the National Academy of Sciences 97 (12), 6242-6244, 2000 | 1060 | 2000 |
| PTEN/PI3K/Akt pathway regulates the side population phenotype and ABCG2 activity in glioma tumor stem-like cells AM Bleau, D Hambardzumyan, T Ozawa, EI Fomchenko, JT Huse, ... Cell stem cell 4 (3), 226-235, 2009 | 975 | 2009 |
| Differential exoprotease activities confer tumor-specific serum peptidome patterns J Villanueva, DR Shaffer, J Philip, CA Chaparro, H Erdjument-Bromage, ... The Journal of clinical investigation 116 (1), 271-284, 2006 | 938 | 2006 |
| Targeting brain cancer: advances in the molecular pathology of malignant glioma and medulloblastoma JT Huse, EC Holland Nature reviews cancer 10 (5), 319-331, 2010 | 936 | 2010 |
| Identification of a multipotent astrocytic stem cell in the immature and adult mouse brain ED Laywell, P Rakic, VG Kukekov, EC Holland, DA Steindler Proceedings of the National Academy of Sciences 97 (25), 13883-13888, 2000 | 928 | 2000 |
| Genomic Analysis of Non-NF2 Meningiomas Reveals Mutations in TRAF7, KLF4, AKT1, and SMO VE Clark, EZ Erson-Omay, A Serin, J Yin, J Cotney, K Özduman, T Avşar, ... Science 339 (6123), 1077-1080, 2013 | 911 | 2013 |
| cIMPACT-NOW update 3: recommended diagnostic criteria for “Diffuse astrocytic glioma, IDH-wildtype, with molecular features of glioblastoma, WHO grade IV” DJ Brat, K Aldape, H Colman, EC Holland, DN Louis, RB Jenkins, ... Acta neuropathologica 136, 805-810, 2018 | 866 | 2018 |
| Challenges to curing primary brain tumours K Aldape, KM Brindle, L Chesler, R Chopra, A Gajjar, MR Gilbert, ... Nature reviews Clinical oncology 16 (8), 509-520, 2019 | 834 | 2019 |
| PDGF autocrine stimulation dedifferentiates cultured astrocytes and induces oligodendrogliomas and oligoastrocytomas from neural progenitors and astrocytes in vivo C Dai, JC Celestino, Y Okada, DN Louis, GN Fuller, EC Holland Genes & development 15 (15), 1913-1925, 2001 | 833 | 2001 |
| HIV-1 tat trans-activation requires the loop sequence within tar S Feng, EC Holland Nature 334 (6178), 165-167, 1988 | 785 | 1988 |
| The PTEN-regulating microRNA miR-26a is amplified in high-grade glioma and facilitates gliomagenesis in vivo JT Huse, C Brennan, D Hambardzumyan, B Wee, J Pena, ... Genes & development 23 (11), 1327-1337, 2009 | 674 | 2009 |
| Glioblastoma subclasses can be defined by activity among signal transduction pathways and associated genomic alterations C Brennan, H Momota, D Hambardzumyan, T Ozawa, A Tandon, ... PloS one 4 (11), e7752, 2009 | 670 | 2009 |
| The brain tumor microenvironment NA Charles, EC Holland, R Gilbertson, R Glass, H Kettenmann Glia 59 (8), 1169-1180, 2011 | 642 | 2011 |
| The tumor microenvironment underlies acquired resistance to CSF-1R inhibition in gliomas DF Quail, RL Bowman, L Akkari, ML Quick, AJ Schuhmacher, JT Huse, ... Science 352 (6288), aad3018, 2016 | 641 | 2016 |
| A constitutively active epidermal growth factor receptor cooperates with disruption of G1 cell-cycle arrest pathways to induce glioma-like lesions in mice EC Holland, WP Hively, RA DePinho, HE Varmus Genes & development 12 (23), 3675-3685, 1998 | 641 | 1998 |
| Intratumoral heterogeneity of receptor tyrosine kinases EGFR and PDGFRA amplification in glioblastoma defines subpopulations with distinct growth factor response NJ Szerlip, A Pedraza, D Chakravarty, M Azim, J McGuire, Y Fang, ... Proceedings of the National Academy of Sciences 109 (8), 3041-3046, 2012 | 638 | 2012 |
