Adenovirus E4ORF1-induced MYC activation promotes host cell anabolic glucose metabolism and virus replication M Thai, NA Graham, D Braas, M Nehil, E Komisopoulou, SK Kurdistani, ... Cell metabolism 19 (4), 694-701, 2014 | 275 | 2014 |
Lactate dehydrogenase activity drives hair follicle stem cell activation A Flores, J Schell, AS Krall, D Jelinek, M Miranda, M Grigorian, D Braas, ... Nature cell biology 19 (9), 1017-1026, 2017 | 272 | 2017 |
BRAF inhibitor vemurafenib improves the antitumor activity of adoptive cell immunotherapy RC Koya, S Mok, N Otte, KJ Blacketor, B Comin-Anduix, PC Tumeh, ... Cancer research 72 (16), 3928-3937, 2012 | 260 | 2012 |
Glucose deprivation activates a metabolic and signaling amplification loop leading to cell death NA Graham, M Tahmasian, B Kohli, E Komisopoulou, M Zhu, I Vivanco, ... Molecular systems biology 8 (1), 589, 2012 | 234 | 2012 |
Phosphoproteome integration reveals patient-specific networks in prostate cancer JM Drake, EO Paull, NA Graham, JK Lee, BA Smith, B Titz, T Stoyanova, ... Cell 166 (4), 1041-1054, 2016 | 231 | 2016 |
MCT1 modulates cancer cell pyruvate export and growth of tumors that co-express MCT1 and MCT4 CS Hong, NA Graham, W Gu, CE Camacho, V Mah, EL Maresh, M Alavi, ... Cell reports 14 (7), 1590-1601, 2016 | 221 | 2016 |
DNA-PKcs-mediated transcriptional regulation drives prostate cancer progression and metastasis JF Goodwin, V Kothari, JM Drake, S Zhao, E Dylgjeri, JL Dean, ... Cancer cell 28 (1), 97-113, 2015 | 184 | 2015 |
Oncogene-specific activation of tyrosine kinase networks during prostate cancer progression JM Drake, NA Graham, T Stoyanova, A Sedghi, AS Goldstein, H Cai, ... Proceedings of the National Academy of Sciences 109 (5), 1643-1648, 2012 | 181 | 2012 |
MOTS-c is an exercise-induced mitochondrial-encoded regulator of age-dependent physical decline and muscle homeostasis JC Reynolds, RW Lai, JST Woodhead, JH Joly, CJ Mitchell, ... Nature communications 12 (1), 470, 2021 | 132 | 2021 |
Metastatic castration-resistant prostate cancer reveals intrapatient similarity and interpatient heterogeneity of therapeutic kinase targets JM Drake, NA Graham, JK Lee, T Stoyanova, CM Faltermeier, S Sud, ... Proceedings of the National Academy of Sciences 110 (49), E4762-E4769, 2013 | 130 | 2013 |
A microfluidic platform for systems pathology: multiparameter single-cell signaling measurements of clinical brain tumor specimens J Sun, MD Masterman-Smith, NA Graham, J Jiao, J Mottahedeh, DR Laks, ... Cancer research 70 (15), 6128-6138, 2010 | 118 | 2010 |
A synthetic lethal drug combination mimics glucose deprivation–induced cancer cell death in the presence of glucose JH Joly, A Delfarah, PS Phung, S Parrish, NA Graham Journal of Biological Chemistry 295 (5), 1350-1365, 2020 | 92 | 2020 |
Recurrent patterns of DNA copy number alterations in tumors reflect metabolic selection pressures NA Graham, A Minasyan, A Lomova, A Cass, NG Balanis, M Friedman, ... Molecular systems biology 13 (2), 914, 2017 | 80 | 2017 |
Tunable interplay between epidermal growth factor and cell–cell contact governs the spatial dynamics of epithelial growth JH Kim, K Kushiro, NA Graham, AR Asthagiri Proceedings of the National Academy of Sciences 106 (27), 11149-11153, 2009 | 80 | 2009 |
Deep protein methylation profiling by combined chemical and immunoaffinity approaches reveals novel PRMT1 targets NG Hartel, B Chew, J Qin, J Xu, NA Graham Molecular & Cellular Proteomics 18 (11), 2149-2164, 2019 | 49 | 2019 |
Increased lactate dehydrogenase activity is dispensable in squamous carcinoma cells of origin A Flores, S Sandoval-Gonzalez, R Takahashi, A Krall, L Sathe, L Wei, ... Nature communications 10 (1), 91, 2019 | 45 | 2019 |
Effect of protein corona on nanoparticle–plasma membrane and nanoparticle–biomimetic membrane interactions L Wang, N Hartel, K Ren, NA Graham, N Malmstadt Environmental Science: Nano 7 (3), 963-974, 2020 | 44 | 2020 |
Quantitative proteomics and metabolomics reveal biomarkers of disease as potential immunotherapy targets and indicators of therapeutic efficacy MA MacMullan, ZS Dunn, NA Graham, L Yang, P Wang Theranostics 9 (25), 7872, 2019 | 44 | 2019 |
Inhibition of nucleotide synthesis promotes replicative senescence of human mammary epithelial cells A Delfarah, S Parrish, JA Junge, J Yang, F Seo, S Li, J Mac, P Wang, ... Journal of Biological Chemistry 294 (27), 10564-10578, 2019 | 42 | 2019 |
The impact of ex vivo clinical grade activation protocols on human T-cell phenotype and function for the generation of genetically modified cells for adoptive cell transfer therapy PC Tumeh, RC Koya, T Chodon, NA Graham, TG Graeber, ... Journal of Immunotherapy 33 (8), 759-768, 2010 | 40 | 2010 |