Extracellular vesicles in cancer: exosomes, microvesicles and the emerging role of large oncosomes VR Minciacchi, MR Freeman, D Di Vizio Seminars in cell & developmental biology 40, 41-51, 2015 | 1021 | 2015 |
Cholesterol targeting alters lipid raft composition and cell survival in prostate cancer cells and xenografts L Zhuang, J Kim, RM Adam, KR Solomon, MR Freeman The Journal of clinical investigation 115 (4), 959-968, 2005 | 677 | 2005 |
Peripheral blood T lymphocytes and lymphocytes infiltrating human cancers express vascular endothelial growth factor: a potential role for T cells in angiogenesis MR Freeman, FX Schneck, ML Gagnon, C Corless, S Soker, K Niknejad, ... Cancer Research 55 (18), 4140-4145, 1995 | 530 | 1995 |
Fibroblast-mediated acceleration of human epithelial tumor growth in vivo. JL Camps, SM Chang, TC Hsu, MR Freeman, SJ Hong, HE Zhau, ... Proceedings of the National Academy of Sciences 87 (1), 75-79, 1990 | 482 | 1990 |
Oncosome formation in prostate cancer: association with a region of frequent chromosomal deletion in metastatic disease D Di Vizio, J Kim, MH Hager, M Morello, W Yang, CJ Lafargue, LD True, ... Cancer research 69 (13), 5601-5609, 2009 | 469 | 2009 |
Large oncosomes in human prostate cancer tissues and in the circulation of mice with metastatic disease D Di Vizio, M Morello, AC Dudley, PW Schow, RM Adam, S Morley, ... The American journal of pathology 181 (5), 1573-1584, 2012 | 448 | 2012 |
Formation of urothelial structures in vivo from dissociated cells attached to biodegradable polymer scaffolds in vitro A Atala, JP Vacanti, CA Peters, J Mandell, AB Retik, MR Freeman The Journal of urology 148 (2), 658-662, 1992 | 408 | 1992 |
T lymphocytes synthesize and export heparin-binding epidermal growth factor-like growth factor and basic fibroblast growth factor, mitogens for vascular cells and fibroblasts … S Blotnick, GE Peoples, MR Freeman, TJ Eberlein, M Klagsbrun Proceedings of the National Academy of Sciences 91 (8), 2890-2894, 1994 | 398 | 1994 |
Large oncosomes contain distinct protein cargo and represent a separate functional class of tumor-derived extracellular vesicles VR Minciacchi, S You, C Spinelli, S Morley, M Zandian, PJ Aspuria, ... Oncotarget 6 (13), 11327, 2015 | 390 | 2015 |
Cholesterol-rich lipid rafts mediate akt-regulated survival in prostate cancer cells L Zhuang, J Lin, ML Lu, KR Solomon, MR Freeman Cancer research 62 (8), 2227-2231, 2002 | 389 | 2002 |
Large extracellular vesicles carry most of the tumour DNA circulating in prostate cancer patient plasma T Vagner, C Spinelli, VR Minciacchi, L Balaj, M Zandian, A Conley, ... Journal of extracellular vesicles 7 (1), 1505403, 2018 | 365 | 2018 |
Implantation in vivo and retrieval of artificial structures consisting of rabbit and human urothelium and human bladder muscle A Atala, MR Freeman, JP Vacanti, J Shepard, AB Retik The Journal of urology 150 (2), 608-612, 1993 | 348 | 1993 |
Marked Disturbance of Calcium Homeostasis in Mice With Targeted Disruption of the Trpv6 Calcium Channel Gene SDC Bianco, JB Peng, H Takanaga, Y Suzuki, A Crescenzi, CH Kos, ... Journal of bone and mineral research 22 (2), 274-285, 2007 | 336 | 2007 |
Increased incidence of matrix metalloproteinases in urine of cancer patients MA Moses, D Wiederschain, KR Loughlin, D Zurakowski, CC Lamb, ... Cancer research 58 (7), 1395-1399, 1998 | 335 | 1998 |
Phenotypic and cytogenetic characterization of human bladder urothelia expanded in vitro BG Cilento, MR Freeman, FX Schneck, AB Retik, A Atala The Journal of urology 152 (2), 665-670, 1994 | 327 | 1994 |
Cholesterol and prostate cancer MR Freeman, KR Solomon Journal of cellular biochemistry 91 (1), 54-69, 2004 | 324 | 2004 |
Calcium-selective ion channel, CaT1, is apically localized in gastrointestinal tract epithelia and is aberrantly expressed in human malignancies L Zhuang, JB Peng, L Tou, H Takanaga, RM Adam, MA Hediger, ... Laboratory investigation 82 (12), 1755-1764, 2002 | 321 | 2002 |
Proteome scale characterization of human S-acylated proteins in lipid raft-enriched and non-raft membranes W Yang, D Di Vizio, M Kirchner, H Steen, MR Freeman Molecular & Cellular Proteomics 9 (1), 54-70, 2010 | 318 | 2010 |
Plasma levels of vascular endothelial growth factor are increased in patients with metastatic prostate cancer JLF Duque, KR Loughlin, RM Adam, PW Kantoff, D Zurakowski, ... Urology 54 (3), 523-527, 1999 | 316 | 1999 |
The phosphatidylinositol 3′-kinase pathway is a dominant growth factor-activated cell survival pathway in LNCaP human prostate carcinoma cells J Lin, RM Adam, E Santiestevan, MR Freeman Cancer research 59 (12), 2891-2897, 1999 | 313 | 1999 |