An RNA gene expressed during cortical development evolved rapidly in humans KS Pollard, SR Salama, N Lambert, MA Lambot, S Coppens, JS Pedersen, ... Nature 443 (7108), 167-172, 2006 | 1182 | 2006 |
RNase III cleaves eukaryotic preribosomal RNA at a U3 snoRNP-dependent site S Abou Elela, H Igel, M Ares Cell 85 (1), 115-124, 1996 | 287 | 1996 |
Use of dimethyl sulfate to probe RNA structure in vivo SE Wells, JMX Hughes, AH Igel, M Ares Methods in enzymology, 479-492, 2000 | 241 | 2000 |
The structure of a rigorously conserved RNA element within the SARS virus genome MP Robertson, H Igel, R Baertsch, D Haussler, M Ares Jr, WG Scott PLoS biology 3 (1), e5, 2005 | 187 | 2005 |
Lethal and temperature-sensitive mutations and their suppressors identify an essential structural element in U2 small nuclear RNA. M Ares, AH Igel Genes & development 4 (12a), 2132-2145, 1990 | 167 | 1990 |
CUS2, a yeast homolog of human Tat-SF1, rescues function of misfolded U2 through an unusual RNA recognition motif D Yan, R Perriman, H Igel, KJ Howe, M Neville, M Ares Jr Molecular and cellular biology 18 (9), 5000-5009, 1998 | 102 | 1998 |
CUS1, a suppressor of cold-sensitive U2 snRNA mutations, is a novel yeast splicing factor homologous to human SAP 145. SE Wells, M Neville, M Haynes, J Wang, H Igel, M Ares Genes & development 10 (2), 220-232, 1996 | 93 | 1996 |
Internal sequences that distinguish yeast from metazoan U2 snRNA are unnecessary for pre-mRNA splicing AH Igel, M Ares Jr Nature 334 (6181), 450-453, 1988 | 85 | 1988 |
Conservation of structure and subunit interactions in yeast homologues of splicing factor 3b (SF3b) subunits H IGEL, S WELLS, R PERRIMAN, A MANUEL Jr Rna 4 (1), 1-10, 1998 | 70 | 1998 |
Mutations in an essential U2 small nuclear RNA structure cause cold-sensitive U2 small nuclear ribonucleoprotein function by favoring competing alternative U2 RNA structures MI Zavanelli, JS Britton, AH Igel, M Ares Jr Molecular and cellular biology 14 (3), 1689-1697, 1994 | 60 | 1994 |
Integration of a splicing regulatory network within the meiotic gene expression program of Saccharomyces cerevisiae EM Munding, AH Igel, L Shiue, KM Dorighi, LR Trevino, M Ares Genes & development 24 (23), 2693-2704, 2010 | 44 | 2010 |
Limited functional equivalence of phylogenetic variation in small nuclear RNA: yeast U2 RNA with altered branchpoint complementarity inhibits splicing and produces a dominant … L Miraglia, S Seiwert, AH Igel, M Ares Jr Proceedings of the National Academy of Sciences 88 (16), 7061-7065, 1991 | 34 | 1991 |
Concerted modification of nucleotides at functional centers of the ribosome revealed by single-molecule RNA modification profiling AD Bailey, J Talkish, H Ding, H Igel, A Duran, S Mantripragada, B Paten, ... Elife 11, e76562, 2022 | 31 | 2022 |
Phylogenetic comparison of U2 small nuclear RNA sequences suggests a pseudoknotted structure M Ares Jr, AH Igel UCLA Symp. Mol. Cell. Biol 94, 13-23, 1989 | 25 | 1989 |
Cus2 enforces the first ATP-dependent step of splicing by binding to yeast SF3b1 through a UHM–ULM interaction J Talkish, H Igel, O Hunter, SW Horner, NN Jeffery, JR Leach, JL Jenkins, ... Rna 25 (8), 1020-1037, 2019 | 22 | 2019 |
Rapidly evolving protointrons in Saccharomyces genomes revealed by a hungry spliceosome J Talkish, H Igel, RJ Perriman, L Shiue, S Katzman, EM Munding, ... PLoS genetics 15 (8), e1008249, 2019 | 21 | 2019 |
Mutations define essential and nonessential U2 RNA structures M Ares, AH Igel Molecular Biology Reports 14, 131-132, 1990 | 7 | 1990 |
Broad variation in response of individual introns to splicing inhibitors in a humanized yeast strain O Hunter, J Talkish, J Quick-Cleveland, H Igel, A Tan, S Kuersten, ... RNA 30 (2), 149-170, 2024 | 6 | 2024 |
Intron lariat spliceosomes convert lariats to true circles: implications for intron transposition M Ares, H Igel, S Katzman, JP Donohue Genes & Development 38 (7-8), 322-335, 2024 | 4 | 2024 |
Genetic manipulation of Micromonas-New tools for a marine model alga J Paap, L Sudek, O Matantseva, H Igel, J Muschiol, P Dash, M Ares Jr, ... | | 2023 |