Canonical WNT signaling promotes osteogenesis by directly stimulating Runx2 gene expression T Gaur, CJ Lengner, H Hovhannisyan, RA Bhat, PVN Bodine, BS Komm, ... Journal of Biological Chemistry 280 (39), 33132-33140, 2005 | 1448 | 2005 |
Oxidative stress induces vascular calcification through modulation of the osteogenic transcription factor Runx2 by AKT signaling CH Byon, A Javed, Q Dai, JC Kappes, TL Clemens, VM Darley-Usmar, ... Journal of Biological Chemistry 283 (22), 15319-15327, 2008 | 757 | 2008 |
Runx2 control of organization, assembly and activity of the regulatory machinery for skeletal gene expression GS Stein, JB Lian, AJ Van Wijnen, JL Stein, M Montecino, A Javed, ... Oncogene 23 (24), 4315-4329, 2004 | 653 | 2004 |
Regulatory controls for osteoblast growth and differentiation: role of Runx/Cbfa/AML factors JB Lian, A Javed, SK Zaidi, C Lengner, M Montecino, AJ Van Wijnen, ... Critical Reviews™ in Eukaryotic Gene Expression 14 (1&2), 2004 | 560 | 2004 |
Networks and hubs for the transcriptional control of osteoblastogenesis JB Lian, GS Stein, A Javed, AJ Van Wijnen, JL Stein, M Montecino, ... Reviews in Endocrine and Metabolic Disorders 7 (1-2), 1-16, 2006 | 539 | 2006 |
The Runx2 osteogenic transcription factor regulates matrix metalloproteinase 9 in bone metastatic cancer cells and controls cell invasion J Pratap, A Javed, LR Languino, AJ Van Wijnen, JL Stein, GS Stein, ... Molecular and cellular biology 25 (19), 8581-8591, 2005 | 372 | 2005 |
Smooth Muscle Cell–Specific Runx2 Deficiency Inhibits Vascular CalcificationNovelty and Significance Y Sun, CH Byon, K Yuan, J Chen, X Mao, JM Heath, A Javed, K Zhang, ... Circulation research 111 (5), 543-552, 2012 | 371 | 2012 |
Dlx3 transcriptional regulation of osteoblast differentiation: temporal recruitment of Msx2, Dlx3, and Dlx5 homeodomain proteins to chromatin of the osteocalcin gene MQ Hassan, A Javed, MI Morasso, J Karlin, M Montecino, AJ Van Wijnen, ... Molecular and cellular biology 24 (20), 9248-9261, 2004 | 344 | 2004 |
Subnuclear targeting of Runx/Cbfa/AML factors is essential for tissue-specific differentiation during embryonic development JY Choi, J Pratap, A Javed, SK Zaidi, L Xing, E Balint, S Dalamangas, ... Proceedings of the National Academy of Sciences 98 (15), 8650-8655, 2001 | 338 | 2001 |
Transient upregulation of CBFA1 in response to bone morphogenetic protein‐2 and transforming growth factor β1 in C2C12 myogenic cells coincides with suppression of the myogenic … MH Lee, A Javed, HJ Kim, HI Shin, S Gutierrez, JY Choi, V Rosen, ... Journal of cellular biochemistry 73 (1), 114-125, 1999 | 332 | 1999 |
Groucho/TLE/R-esp proteins associate with the nuclear matrix and repress RUNX (CBF (alpha)/AML/PEBP2 (alpha)) dependent activation of tissue-specific gene transcription A Javed, B Guo, S Hiebert, JY Choi, J Green, SC Zhao, MA Osborne, ... J Cell Sci 113 (12), 2221-2231, 2000 | 305 | 2000 |
Regulatory roles of Runx2 in metastatic tumor and cancer cell interactions with bone J Pratap, JB Lian, A Javed, GL Barnes, AJ Van Wijnen, JL Stein, GS Stein Cancer and Metastasis Reviews 25 (4), 589-600, 2006 | 298 | 2006 |
CCAAT/enhancer-binding proteins (C/EBP) β and δ activate osteocalcin gene transcription and synergize with Runx2 at the C/EBP element to regulate bone-specific expression S Gutierrez, A Javed, DK Tennant, M van Rees, M Montecino, GS Stein, ... Journal of Biological Chemistry 277 (2), 1316-1323, 2002 | 295 | 2002 |
Differential regulation of the two principal Runx2/Cbfa1 n-terminal isoforms in response to bone morphogenetic protein-2 during development of the osteoblast phenotype C Banerjee, A Javed, JY Choi, J Green, V Rosen, AJ Van Wijnen, JL Stein, ... Endocrinology 142 (9), 4026-4039, 2001 | 282 | 2001 |
Cbfβ interacts with Runx2 and has a critical role in bone development M Kundu, A Javed, JP Jeon, A Horner, L Shum, M Eckhaus, M Muenke, ... Nature genetics 32 (4), 639-644, 2002 | 274 | 2002 |
Mitotic occupancy and lineage-specific transcriptional control of rRNA genes by Runx2 DW Young, MQ Hassan, J Pratap, M Galindo, SK Zaidi, S Lee, X Yang, ... Nature 445 (7126), 442-446, 2007 | 267 | 2007 |
Structural coupling of Smad and Runx2 for execution of the BMP2 osteogenic signal A Javed, JS Bae, F Afzal, S Gutierrez, J Pratap, SK Zaidi, Y Lou, ... Journal of Biological Chemistry 283 (13), 8412-8422, 2008 | 265 | 2008 |
BMP2 commitment to the osteogenic lineage involves activation of Runx2 by DLX3 and a homeodomain transcriptional network MQ Hassan, RS Tare, SH Lee, M Mandeville, MI Morasso, A Javed, ... Journal of Biological Chemistry 281 (52), 40515-40526, 2006 | 263 | 2006 |
Expression and regulation of Runx2/Cbfa1 and osteoblast phenotypic markers during the growth and differentiation of human osteoblasts M Prince, C Banerjee, A Javed, J Green, JB Lian, GS Stein, PVN Bodine, ... Journal of cellular biochemistry 80 (3), 424-440, 2001 | 251 | 2001 |
Osteoblast-related transcription factors Runx2 (Cbfa1/AML3) and MSX2 mediate the expression of bone sialoprotein in human metastatic breast cancer cells GL Barnes, A Javed, SM Waller, MH Kamal, KE Hebert, MQ Hassan, ... Cancer research 63 (10), 2631-2637, 2003 | 243 | 2003 |