The human immunodeficiency virus type 1 Vpu protein inhibits NF-κB activation by interfering with βTrCP-mediated degradation of IκB S Bour, C Perrin, H Akari, K Strebel Journal of Biological Chemistry 276 (19), 15920-15928, 2001 | 239 | 2001 |
Human immunodeficiency virus type 1 Vif protein is packaged into the nucleoprotein complex through an interaction with viral genomic RNA MA Khan, C Aberham, S Kao, H Akari, R Gorelick, S Bour, K Strebel Journal of virology 75 (16), 7252-7265, 2001 | 198 | 2001 |
The human immunodeficiency virus type 1 accessory protein Vpu induces apoptosis by suppressing the nuclear factor κB–dependent expression of antiapoptotic factors H Akari, S Bour, S Kao, A Adachi, K Strebel The Journal of experimental medicine 194 (9), 1299-1312, 2001 | 195 | 2001 |
Codon optimization of the HIV-1 vpu and vif genes stabilizes their mRNA and allows for highly efficient Rev-independent expression KL Nguyen, M Llano, H Akari, E Miyagi, EM Poeschla, K Strebel, S Bour Virology 319 (2), 163-175, 2004 | 155 | 2004 |
Nef-induced major histocompatibility complex class I down-regulation is functionally dissociated from its virion incorporation, enhancement of viral infectivity, and CD4 down … H Akari, S Arold, T Fukumori, T Okazaki, K Strebel, A Adachi Journal of virology 74 (6), 2907-2912, 2000 | 132 | 2000 |
Cell-dependent requirement of human immunodeficiency virus type 1 gp41 cytoplasmic tail for Env incorporation into virions H Akari, T Fukumori, A Adachi Journal of virology 74 (10), 4891-4893, 2000 | 120 | 2000 |
Different Effects of Nef-Mediated HLA Class I Down-Regulation on Human Immunodeficiency Virus Type 1-Specific CD8+ T-Cell Cytolytic Activity and Cytokine … H Tomiyama, H Akari, A Adachi, M Takiguchi Journal of virology 76 (15), 7535-7543, 2002 | 110 | 2002 |
Expression of HIV-1 accessory protein Vif is controlled uniquely to be low and optimal by proteasome degradation M Fujita, H Akari, A Sakurai, A Yoshida, T Chiba, K Tanaka, K Strebel, ... Microbes and infection 6 (9), 791-798, 2004 | 99 | 2004 |
Common marmoset (Callithrix jacchus) as a primate model of dengue virus infection: development of high levels of viraemia and demonstration of protective immunity T Omatsu, ML Moi, T Hirayama, T Takasaki, S Nakamura, S Tajima, M Ito, ... Journal of general virology 92 (10), 2272-2280, 2011 | 89 | 2011 |
The HIV‐1 Vpr displays strong anti‐apoptotic activity T Fukumori, H Akari, S Iida, S Hata, S Kagawa, Y Aida, AH Koyama, ... FEBS letters 432 (1-2), 17-20, 1998 | 88 | 1998 |
In VitroImmortalization of Old World Monkey T Lymphocytes withHerpesvirus Saimiri: Its Susceptibility to Infection with Simian Immunodeficiency Viruses H AKARI, K MORI, K TERAO, I OTANI, M FUKASAWA, R MUKAI, ... Virology 218 (2), 382-388, 1996 | 84 | 1996 |
Human immunodeficiency virus type 1 Vif is efficiently packaged into virions during productive but not chronic infection S Kao, H Akari, MA Khan, M Dettenhofer, XF Yu, K Strebel Journal of virology 77 (2), 1131-1140, 2003 | 83 | 2003 |
Peripheral blood CD4+ CD8+ lymphocytes in cynomolgus monkeys are of resting memory T lineage. H Akari, K Terao, Y Murayama, KH Nam, Y Yoshikawa International immunology 9 (4), 591-597, 1997 | 83 | 1997 |
Ubiquitination of APOBEC3 proteins by the Vif–Cullin5–ElonginB–ElonginC complex K Shirakawa, A Takaori-Kondo, M Kobayashi, M Tomonaga, T Izumi, ... Virology 344 (2), 263-266, 2006 | 78 | 2006 |
Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo R Furuta, J Yasunaga, M Miura, K Sugata, A Saito, H Akari, T Ueno, ... PLoS pathogens 13 (11), e1006722, 2017 | 75 | 2017 |
High level expression of human immunodeficiency virus type-1 Vif inhibits viral infectivity by modulating proteolytic processing of the Gag precursor at the p2/nucleocapsid … H Akari, M Fujita, S Kao, MA Khan, M Shehu-Xhilaga, A Adachi, K Strebel Journal of Biological Chemistry 279 (13), 12355-12362, 2004 | 75 | 2004 |
MDM2 is a novel E3 ligase for HIV-1 Vif T Izumi, A Takaori-Kondo, K Shirakawa, H Higashitsuji, K Itoh, K Io, ... Retrovirology 6, 1-12, 2009 | 73 | 2009 |
Gag-specific cytotoxic T-lymphocyte-based control of primary simian immunodeficiency virus replication in a vaccine trial M Kawada, T Tsukamoto, H Yamamoto, N Iwamoto, K Kurihara, A Takeda, ... Journal of virology 82 (20), 10199-10206, 2008 | 70 | 2008 |
Natural selection in the TLR-related genes in the course of primate evolution T Nakajima, H Ohtani, Y Satta, Y Uno, H Akari, T Ishida, A Kimura Immunogenetics 60, 727-735, 2008 | 66 | 2008 |
Role of virus-induced apoptosis in a host defense mechanism against virus infection AH Koyama, H Irie, T Fukumori, S Hata, S Iida, H Akari, A Adach Journal of Medical Investigation 45, 37-46, 1998 | 66 | 1998 |