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Oren Levy
Oren Levy
Lead Investigator, Brigham and Women's Hospital, Harvard Medical School
Email confirmado em partners.org
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Harnessing the mesenchymal stem cell secretome for the treatment of cardiovascular disease
SH Ranganath, O Levy, MS Inamdar, JM Karp
Cell stem cell 10 (3), 244-258, 2012
9472012
Engineering stem cell organoids
X Yin, BE Mead, H Safaee, R Langer, JM Karp, O Levy
Cell stem cell 18 (1), 25-38, 2016
8532016
Nanowired three-dimensional cardiac patches
T Dvir, BP Timko, MD Brigham, SR Naik, SS Karajanagi, O Levy, H Jin, ...
Nature nanotechnology 6 (11), 720-725, 2011
8412011
A complex human gut microbiome cultured in an anaerobic intestine-on-a-chip
S Jalili-Firoozinezhad, FS Gazzaniga, EL Calamari, DM Camacho, ...
Nature biomedical engineering 3 (7), 520-531, 2019
7082019
Shattering barriers toward clinically meaningful MSC therapies
O Levy, R Kuai, EMJ Siren, D Bhere, Y Milton, N Nissar, M De Biasio, ...
Science advances 6 (30), eaba6884, 2020
5432020
Human organ chip models recapitulate orthotopic lung cancer growth, therapeutic responses, and tumor dormancy in vitro
BA Hassell, G Goyal, E Lee, A Sontheimer-Phelps, O Levy, CS Chen, ...
Cell reports 21 (2), 508-516, 2017
4692017
Prevascularization of cardiac patch on the omentum improves its therapeutic outcome
T Dvir, A Kedem, E Ruvinov, O Levy, I Freeman, N Landa, R Holbova, ...
Proceedings of the National Academy of Sciences 106 (35), 14990-14995, 2009
4052009
Quantitative prediction of human pharmacokinetic responses to drugs via fluidically coupled vascularized organ chips
A Herland, BM Maoz, D Das, MR Somayaji, R Prantil-Baun, R Novak, ...
Nature biomedical engineering 4 (4), 421-436, 2020
3782020
Robotic fluidic coupling and interrogation of multiple vascularized organ chips
R Novak, M Ingram, S Marquez, D Das, A Delahanty, A Herland, BM Maoz, ...
Nature biomedical engineering 4 (4), 407-420, 2020
3502020
On-chip recapitulation of clinical bone marrow toxicities and patient-specific pathophysiology
DB Chou, V Frismantas, Y Milton, R David, P Pop-Damkov, D Ferguson, ...
Nature biomedical engineering 4 (4), 394-406, 2020
2572020
Towards an arthritis flare-responsive drug delivery system
N Joshi, J Yan, S Levy, S Bhagchandani, KV Slaughter, NE Sherman, ...
Nature Communications 9 (1), 1275, 2018
2362018
mRNA-engineered mesenchymal stem cells for targeted delivery of interleukin-10 to sites of inflammation
O Levy, W Zhao, LJ Mortensen, S LeBlanc, K Tsang, M Fu, JA Phillips, ...
Blood, The Journal of the American Society of Hematology 122 (14), e23-e32, 2013
2222013
Human colon-on-a-chip enables continuous in vitro analysis of colon mucus layer accumulation and physiology
A Sontheimer-Phelps, DB Chou, A Tovaglieri, TC Ferrante, T Duckworth, ...
Cellular and Molecular Gastroenterology and Hepatology 9 (3), 507-526, 2020
2142020
Modeling radiation injury-induced cell death and countermeasure drug responses in a human Gut-on-a-Chip
S Jalili-Firoozinezhad, R Prantil-Baun, A Jiang, R Potla, T Mammoto, ...
Cell death & disease 9 (2), 223, 2018
1982018
Activation of the ERK1/2 cascade via pulsatile interstitial fluid flow promotes cardiac tissue assembly
T Dvir, O Levy, M Shachar, Y Granot, S Cohen
Tissue engineering 13 (9), 2185-2193, 2007
1142007
Application of biomaterials to advance induced pluripotent stem cell research and therapy
Z Tong, A Solanki, A Hamilos, O Levy, K Wen, X Yin, JM Karp
The EMBO journal 34 (8), 987-1008, 2015
1082015
Functional inactivation of p53 by human T-cell leukemia virus type 1 Tax protein: mechanisms and clinical implications
Y Tabakin-Fix, I Azran, Y Schavinky-Khrapunsky, O Levy, M Aboud
Carcinogenesis 27 (4), 673-681, 2006
1012006
Performance-enhanced mesenchymal stem cells via intracellular delivery of steroids
JA Ankrum, RG Dastidar, JF Ong, O Levy, JM Karp
Scientific reports 4 (1), 4645, 2014
982014
Ectopic lymphoid follicle formation and human seasonal influenza vaccination responses recapitulated in an organ‐on‐a‐chip
G Goyal, P Prabhala, G Mahajan, B Bausk, T Gilboa, L Xie, Y Zhai, ...
Advanced Science 9 (14), 2103241, 2022
822022
A prodrug-doped cellular Trojan Horse for the potential treatment of prostate cancer
O Levy, WN Brennen, E Han, DM Rosen, J Musabeyezu, H Safaee, ...
Biomaterials 91, 140-150, 2016
822016
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