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Eduardo Henrique Silva Sousa
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An oxygen-sensing diguanylate cyclase and phosphodiesterase couple for c-di-GMP control
JR Tuckerman, G Gonzalez, EHS Sousa, X Wan, JA Saito, M Alam, ...
Biochemistry 48 (41), 9764-9774, 2009
2762009
DosT and DevS are oxygen‐switched kinases in Mycobacterium tuberculosis
EHS Sousa, JR Tuckerman, G Gonzalez, MA Gilles‐Gonzalez
Protein Science 16 (8), 1708-1719, 2007
1922007
An inorganic iron complex that inhibits wild-type and an isoniazid-resistant mutant 2-trans-enoyl-ACP (CoA) reductase from Mycobacterium tuberculosis
JS Oliveira, EHS Sousa, LA Basso, M Palaci, R Dietze, DS Santos, ...
Chemical communications, 312-313, 2004
932004
Aryl-substituted ruthenium (II) complexes: a strategy for enhanced photocleavage and efficient DNA binding
FD Abreu, TF Paulo, MH Gehlen, RA Ando, LGF Lopes, ACS Gondim, ...
Inorganic Chemistry 56 (15), 9084-9096, 2017
632017
The potent anti-cancer activity of Dioclea lasiocarpa lectin
ACS Gondim, I Romero-Canelon, EHS Sousa, CA Blindauer, JS Butler, ...
Journal of Inorganic Biochemistry 175, 179-189, 2017
592017
Slow-onset inhibition of 2-trans-enoyl-ACP (CoA) reductase from Mycobacterium tuberculosis by an inorganic complex
JS Oliveira, EHS de Sousa, ON de Souza, DS Santos, LA Basso
Current pharmaceutical design 12 (19), 2409-2424, 2006
592006
Thiol-activated HNO release from a ruthenium antiangiogenesis complex and HIF-1α inhibition for cancer therapy
EH Silva Sousa, LA Ridnour, FS Gouveia Jr, CD Silva da Silva, DA Wink, ...
ACS Chemical Biology 11 (7), 2057-2065, 2016
572016
Isoniazid metal complex reactivity and insights for a novel anti-tuberculosis drug design
EHS Sousa, LA Basso, DS Santos, ICN Diógenes, E Longhinotti, ...
JBIC Journal of Biological Inorganic Chemistry 17, 275-283, 2012
542012
Oxygen blocks the reaction of the FixL− FixJ complex with ATP but does not influence binding of FixJ or ATP to FixL
EHS Sousa, G Gonzalez, MA Gilles-Gonzalez
Biochemistry 44 (46), 15359-15365, 2005
502005
Mechanism and biological implications of the NO release of cis-[Ru (bpy) 2L (NO)] n+ complexes: A key role of physiological thiols
FON Silva, MCL Cândido, AKM Holanda, ICN Diógenes, EHS Sousa, ...
Journal of Inorganic Biochemistry 105 (5), 624-629, 2011
472011
Synthesis of bifunctional mesoporous silica spheres as potential adsorbent for ions in solution
ECC Gomes, AF de Sousa, PHM Vasconcelos, DQ Melo, ICN Diógenes, ...
Chemical Engineering Journal 214, 27-33, 2013
452013
A memory of oxygen binding explains the dose response of the heme-based sensor FixL
EHS Sousa, JR Tuckerman, G Gonzalez, MA Gilles-Gonzalez
Biochemistry 46 (21), 6249-6257, 2007
432007
A proximal arginine R206 participates in switching of the Bradyrhizobium japonicum FixL oxygen sensor
MA Gilles-Gonzalez, AI Caceres, EHS Sousa, DR Tomchick, C Brautigam, ...
Journal of molecular biology 360 (1), 80-89, 2006
422006
The ruthenium NO donor,[Ru (bpy) 2 (NO) SO3](PF6), inhibits inflammatory pain: involvement of TRPV1 and cGMP/PKG/ATP-sensitive potassium channel signaling pathway
L Staurengo-Ferrari, SS Mizokami, JJ Silva, FON da Silva, EHS Sousa, ...
Pharmacology Biochemistry and Behavior 105, 157-165, 2013
412013
Hell’s Gate globin I: An acid and thermostable bacterial hemoglobin resembling mammalian neuroglobin
AH Teh, JA Saito, A Baharuddin, JR Tuckerman, JS Newhouse, M Kanbe, ...
FEBS letters 585 (20), 3250-3258, 2011
402011
The nitric oxide donor cis-[Ru (bpy) 2 (SO3) NO](PF6) increases gastric mucosa protection in mice–Involvement of the soluble guanylate cyclase/KATP pathway
APM Santana, BM Tavares, LT Lucetti, FS Gouveia Jr, RA Ribeiro, ...
Nitric Oxide 45, 35-42, 2015
382015
Nitro-imidazole-based ruthenium complexes with antioxidant and anti-inflammatory activities
GL Sasahara, FSG Júnior, R de Oliveira Rodrigues, DS Zampieri, ...
Journal of Inorganic Biochemistry 206, 111048, 2020
372020
Electron transfer kinetics and mechanistic study of the thionicotinamide coordinated to the pentacyanoferrate (III)/(II) complexes: a model system for the in vitro activation …
EHS Sousa, DL Pontes, ICN Diogenes, LGF Lopes, JS Oliveira, LA Basso, ...
Journal of inorganic biochemistry 99 (2), 368-375, 2005
372005
A biphosphinic ruthenium complex with potent anti-bacterial and anti-cancer activity
JM da Silveira Carvalho, AH de Morais Batista, NAP Nogueira, ...
New Journal of Chemistry 41 (21), 13085-13095, 2017
362017
Activity of IQG-607, a new orally active compound, in a murine model of Mycobacterium tuberculosis infection
VS Rodrigues-Junior, A dos Santos Junior, AJ Dos Santos, CZ Schneider, ...
International journal of antimicrobial agents 40 (2), 182-185, 2012
362012
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