Genetic effects on gene expression across human tissues GTEx Consortium Lead analysts: Aguet François 1 Brown Andrew A. 2 3 4 Castel ... Nature 550 (7675), 204-213, 2017 | 3609 | 2017 |
The GTEx Consortium atlas of genetic regulatory effects across human tissues GTEx Consortium Science 369 (6509), 1318-1330, 2020 | 3467 | 2020 |
A reference map of the human binary protein interactome K Luck, DK Kim, L Lambourne, K Spirohn, BE Begg, W Bian, R Brignall, ... Nature 580 (7803), 402-408, 2020 | 1092 | 2020 |
The impact of sex on gene expression across human tissues M Oliva, M Muñoz-Aguirre, S Kim-Hellmuth, V Wucher, ADH Gewirtz, ... Science 369 (6509), eaba3066, 2020 | 895 | 2020 |
Network motifs in integrated cellular networks of transcription–regulation and protein–protein interaction E Yeger-Lotem, S Sattath, N Kashtan, S Itzkovitz, R Milo, RY Pinter, ... Proceedings of the National Academy of Sciences 101 (16), 5934-5939, 2004 | 696 | 2004 |
A quantitative proteome map of the human body L Jiang, M Wang, S Lin, R Jian, X Li, J Chan, G Dong, H Fang, ... Cell 183 (1), 269-283. e19, 2020 | 384 | 2020 |
Bridging high-throughput genetic and transcriptional data reveals cellular responses to alpha-synuclein toxicity E Yeger-Lotem, L Riva, LJ Su, AD Gitler, AG Cashikar, OD King, ... Nature genetics 41 (3), 316-323, 2009 | 340 | 2009 |
Alignment of metabolic pathways RY Pinter, O Rokhlenko, E Yeger-Lotem, M Ziv-Ukelson Bioinformatics 21 (16), 3401-3408, 2005 | 281 | 2005 |
Aging promotes reorganization of the CD4 T cell landscape toward extreme regulatory and effector phenotypes Y Elyahu, I Hekselman, I Eizenberg-Magar, O Berner, I Strominger, ... Science advances 5 (8), eaaw8330, 2019 | 237 | 2019 |
Compounds from an unbiased chemical screen reverse both ER-to-Golgi trafficking defects and mitochondrial dysfunction in Parkinson’s disease models LJ Su, PK Auluck, TF Outeiro, E Yeger-Lotem, JA Kritzer, DF Tardiff, ... Disease models & mechanisms 3 (3-4), 194-208, 2010 | 225 | 2010 |
Co-expression networks reveal the tissue-specific regulation of transcription and splicing A Saha, Y Kim, ADH Gewirtz, B Jo, C Gao, IC McDowell, BE Engelhardt, ... Genome research 27 (11), 1843-1858, 2017 | 184 | 2017 |
Transcriptomic signatures across human tissues identify functional rare genetic variation NM Ferraro, BJ Strober, J Einson, NS Abell, F Aguet, AN Barbeira, ... Science 369 (6509), eaaz5900, 2020 | 149 | 2020 |
Mechanisms of tissue and cell-type specificity in heritable traits and diseases I Hekselman, E Yeger-Lotem Nature Reviews Genetics 21 (3), 137-150, 2020 | 149 | 2020 |
Population-scale tissue transcriptomics maps long non-coding RNAs to complex disease OM de Goede, DC Nachun, NM Ferraro, MJ Gloudemans, AS Rao, ... Cell 184 (10), 2633-2648. e19, 2021 | 147 | 2021 |
Cancer evolution is associated with pervasive positive selection on globally expressed genes SL Ostrow, R Barshir, J DeGregori, E Yeger-Lotem, R Hershberg PLoS genetics 10 (3), e1004239, 2014 | 120 | 2014 |
Dynamic voting for consistent primary components D Dolev, I Keidar, EY Lotem Proceedings of the sixteenth annual ACM symposium on Principles of …, 1997 | 101 | 1997 |
Human protein interaction networks across tissues and diseases E Yeger-Lotem, R Sharan Frontiers in genetics 6, 257, 2015 | 100 | 2015 |
Comparative analysis of human tissue interactomes reveals factors leading to tissue-specific manifestation of hereditary diseases R Barshir, O Shwartz, IY Smoly, E Yeger-Lotem PLoS computational biology 10 (6), e1003632, 2014 | 96 | 2014 |
Chromosomal organization is shaped by the transcription regulatory network R Hershberg, E Yeger-Lotem, H Margalit Trends in genetics 21 (3), 138-142, 2005 | 89 | 2005 |
Multicellular communities are perturbed in the aging human brain and Alzheimer’s disease A Cain, M Taga, C McCabe, GS Green, I Hekselman, CC White, DI Lee, ... Nature neuroscience 26 (7), 1267-1280, 2023 | 87 | 2023 |