| Erratum: Structure of the αβ tubulin dimer by electron crystallography E Nogales, SG Wolf, KH Downing Nature 393 (6681), 191-191, 1998 | 2922 | 1998 |
| Structures of Cas9 endonucleases reveal RNA-mediated conformational activation M Jinek, F Jiang, DW Taylor, SH Sternberg, E Kaya, E Ma, C Anders, ... Science 343 (6176), 1247997, 2014 | 1653 | 2014 |
| High-resolution model of the microtubule E Nogales, M Whittaker, RA Milligan, KH Downing Cell 96 (1), 79-88, 1999 | 1546 | 1999 |
| Refined structure of αβ-tubulin at 3.5 Å resolution J Löwe, H Li, KH Downing, E Nogales Journal of molecular biology 313 (5), 1045-1057, 2001 | 1485 | 2001 |
| Structural insights into microtubule function E Nogales Annual review of biophysics and biomolecular structure 30 (1), 397-420, 2001 | 1454 | 2001 |
| High-resolution microtubule structures reveal the structural transitions in αβ-tubulin upon GTP hydrolysis GM Alushin, GC Lander, EH Kellogg, R Zhang, D Baker, E Nogales Cell 157 (5), 1117-1129, 2014 | 794 | 2014 |
| Complete subunit architecture of the proteasome regulatory particle GC Lander, E Estrin, ME Matyskiela, C Bashore, E Nogales, A Martin Nature 482 (7384), 186-191, 2012 | 757 | 2012 |
| Structures of a CRISPR-Cas9 R-loop complex primed for DNA cleavage F Jiang, DW Taylor, JS Chen, JE Kornfeld, K Zhou, AJ Thompson, ... Science 351 (6275), 867-871, 2016 | 740 | 2016 |
| Tubulin and FtsZ form a distinct family of GTPases E Nogales, KH Downing, LA Amos, J Löwe Nature structural biology 5 (6), 451-458, 1998 | 702 | 1998 |
| A common pharmacophore for epothilone and taxanes: molecular basis for drug resistance conferred by tubulin mutations in human cancer cells P Giannakakou, R Gussio, E Nogales, KH Downing, D Zaharevitz, ... Proceedings of the National Academy of Sciences 97 (6), 2904-2909, 2000 | 629 | 2000 |
| Structures of the RNA-guided surveillance complex from a bacterial immune system B Wiedenheft, GC Lander, K Zhou, MM Jore, SJJ Brouns, J Van Der Oost, ... Nature 477 (7365), 486-489, 2011 | 609 | 2011 |
| Microtubule structure at 8 Å resolution H Li, DJ DeRosier, WV Nicholson, E Nogales, KH Downing Structure 10 (10), 1317-1328, 2002 | 526 | 2002 |
| Structure of tubulin at 6.5 Å and location of the taxol-binding site E Nogales, S Grayer Wolf, IA Khan, RF Ludueña, KH Downing Nature 375 (6530), 424-427, 1995 | 524 | 1995 |
| The development of cryo-EM into a mainstream structural biology technique E Nogales Nature methods 13 (1), 24-27, 2016 | 521 | 2016 |
| The binding conformation of Taxol in β-tubulin: A model based on electron crystallographic density JP Snyder, JH Nettles, B Cornett, KH Downing, E Nogales Proceedings of the National Academy of Sciences 98 (9), 5312-5316, 2001 | 516 | 2001 |
| Mechanistic origin of microtubule dynamic instability and its modulation by EB proteins R Zhang, GM Alushin, A Brown, E Nogales Cell 162 (4), 849-859, 2015 | 490 | 2015 |
| CasX enzymes comprise a distinct family of RNA-guided genome editors JJ Liu, N Orlova, BL Oakes, E Ma, HB Spinner, KLM Baney, J Chuck, ... Nature 566 (7743), 218-223, 2019 | 466 | 2019 |
| Cryo-EM: a unique tool for the visualization of macromolecular complexity E Nogales, SHW Scheres Molecular cell 58 (4), 677-689, 2015 | 460 | 2015 |
| Tubulin and microtubule structure KH Downing, E Nogales Current opinion in cell biology 10 (1), 16-22, 1998 | 396 | 1998 |
| Near-atomic model of microtubule-tau interactions EH Kellogg, NMA Hejab, S Poepsel, KH Downing, F DiMaio, E Nogales Science 360 (6394), 1242-1246, 2018 | 392 | 2018 |
David G. DRUBINProfessor Molecular and Cell Biology, University of California, BerkeleyEmail confirmado em berkeley.edu
