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David Breault
David Breault
Associate Professor of Pediatrics, Harvard Medical School
Email confirmado em childrens.harvard.edu
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Defining molecular cornerstones during fibroblast to iPS cell reprogramming in mouse
M Stadtfeld, N Maherali, DT Breault, K Hochedlinger
Cell stem cell 2 (3), 230-240, 2008
10982008
A complex human gut microbiome cultured in an anaerobic intestine-on-a-chip
S Jalili-Firoozinezhad, FS Gazzaniga, EL Calamari, DM Camacho, ...
Nature biomedical engineering 3 (7), 520-531, 2019
7082019
Development of a primary human Small Intestine-on-a-Chip using biopsy-derived organoids
M Kasendra, A Tovaglieri, A Sontheimer-Phelps, S Jalili-Firoozinezhad, ...
Scientific reports 8 (1), 1-14, 2018
7022018
Mouse telomerase reverse transcriptase (mTert) expression marks slowly cycling intestinal stem cells
RK Montgomery, DL Carlone, CA Richmond, L Farilla, MEG Kranendonk, ...
Proceedings of the National Academy of Sciences 108 (1), 179-184, 2011
6552011
Intestinal enteroendocrine lineage cells possess homeostatic and injury-inducible stem cell activity
KS Yan, O Gevaert, GXY Zheng, B Anchang, CS Probert, KA Larkin, ...
Cell stem cell 21 (1), 78-90. e6, 2017
3692017
Frizzled proteins are colonic epithelial receptors for C. difficile toxin B
L Tao, J Zhang, P Meraner, A Tovaglieri, X Wu, R Gerhard, X Zhang, ...
Nature 538 (7625), 350-355, 2016
3112016
Human colon-on-a-chip enables continuous in vitro analysis of colon mucus layer accumulation and physiology
A Sontheimer-Phelps, DB Chou, A Tovaglieri, TC Ferrante, T Duckworth, ...
Cellular and Molecular Gastroenterology and Hepatology 9 (3), 507-526, 2020
2142020
Adrenocortical zonation results from lineage conversion of differentiated zona glomerulosa cells
BD Freedman, PB Kempna, DL Carlone, MS Shah, NA Guagliardo, ...
Developmental cell 26 (6), 666-673, 2013
2062013
The adrenal cortex and its disorders
WL Miller, CE Flück, DT Breault, BJ Feldman
Sperling Pediatric Endocrinology, 425-490, 2021
1902021
Generation of mTert-GFP mice as a model to identify and study tissue progenitor cells
DT Breault, IM Min, DL Carlone, LG Farilla, DM Ambruzs, DE Henderson, ...
Proceedings of the National Academy of Sciences 105 (30), 10420-10425, 2008
1822008
Reprogrammed stomach tissue as a renewable source of functional β cells for blood glucose regulation
C Ariyachet, A Tovaglieri, G Xiang, J Lu, MS Shah, CA Richmond, ...
Cell stem cell 18 (3), 410-421, 2016
1802016
Species-specific enhancement of enterohemorrhagic E. coli pathogenesis mediated by microbiome metabolites
A Tovaglieri, A Sontheimer-Phelps, A Geirnaert, R Prantil-Baun, ...
Microbiome 7, 1-21, 2019
1382019
Wnt secretion from epithelial cells and subepithelial myofibroblasts is not required in the mouse intestinal stem cell niche in vivo
AK San Roman, CD Jayewickreme, LC Murtaugh, RA Shivdasani
Stem cell reports 2 (2), 127-134, 2014
1362014
Fully synthetic matrices for in vitro culture of primary human intestinal enteroids and endometrial organoids
V Hernandez-Gordillo, T Kassis, A Lampejo, GH Choi, ME Gamboa, ...
Biomaterials 254, 120125, 2020
1312020
Small intestinal stem cell markers
RK Montgomery, DT Breault
Journal of anatomy 213 (1), 52-58, 2008
1172008
Sulfated glycosaminoglycans and low-density lipoprotein receptor contribute to Clostridium difficile toxin A entry into cells
L Tao, S Tian, J Zhang, Z Liu, L Robinson-McCarthy, SI Miyashita, ...
Nature microbiology 4 (10), 1760-1769, 2019
1092019
Guidelines for the development of comprehensive care centers for congenital adrenal hyperplasia: guidance from the CARES Foundation initiative
RJ Auchus, SF Witchel, KR Leight, J Aisenberg, R Azziz, TA Bachega, ...
International journal of pediatric endocrinology 2010, 1-17, 2010
1082010
Primary human colonic mucosal barrier crosstalk with super oxygen-sensitive Faecalibacterium prausnitzii in continuous culture
J Zhang, YJ Huang, JY Yoon, J Kemmitt, C Wright, K Schneider, ...
Med 2 (1), 74-98. e9, 2021
1062021
The circadian clock gene BMAL1 coordinates intestinal regeneration
K Stokes, A Cooke, H Chang, DR Weaver, DT Breault, P Karpowicz
Cellular and molecular gastroenterology and hepatology 4 (1), 95-114, 2017
1052017
PKA signaling drives reticularis differentiation and sexually dimorphic adrenal cortex renewal
T Dumontet, I Sahut-Barnola, A Septier, N Montanier, I Plotton, ...
JCI insight 3 (2), e98394, 2018
1032018
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