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Sarah Catherine Brennan
Sarah Catherine Brennan
Endocrinology Advanced Trainee, Westmead Hospital & Research Affiliate at The University of Sydney
Email confirmado em sydney.edu.au
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Structural mechanism of ligand activation in human calcium-sensing receptor
Y Geng, L Mosyak, I Kurinov, H Zuo, E Sturchler, TC Cheng, ...
Elife 5, e13662, 2016
2672016
Calcium-sensing receptor antagonists abrogate airway hyperresponsiveness and inflammation in allergic asthma
PL Yarova, AL Stewart, V Sathish, RD Britt Jr, MA Thompson, AP P. Lowe, ...
Science translational medicine 7 (284), 284ra60-284ra60, 2015
1842015
Calcium sensing receptor signalling in physiology and cancer
SC Brennan, U Thiem, S Roth, A Aggarwal, IS Fetahu, S Tennakoon, ...
Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1833 (7), 1732-1744, 2013
1792013
The vascular Ca2+-sensing receptor regulates blood vessel tone and blood pressure
M Schepelmann, PL Yarova, I Lopez-Fernandez, TS Davies, SC Brennan, ...
American Journal of Physiology-Cell Physiology 310 (3), C193-C204, 2016
952016
Regulation of cellular signal transduction pathways by the extracellular calcium-sensing receptor
SC Brennan, AD Conigrave
Current pharmaceutical biotechnology 10 (3), 270-281, 2009
752009
Comparative expression of the extracellular calcium-sensing receptor in the mouse, rat, and human kidney
JAZ Graca, M Schepelmann, SC Brennan, J Reens, W Chang, P Yan, ...
American Journal of Physiology-Renal Physiology 310 (6), F518-F533, 2016
712016
Physiological significance of L-amino acid sensing by extracellular Ca2+-sensing receptors
AD Conigrave, HC Mun, SC Brennan
Biochemical Society Transactions 35 (5), 1195-1198, 2007
682007
Emerging roles of the extracellular calcium-sensing receptor in nutrient sensing: control of taste modulation and intestinal hormone secretion
SC Brennan, TS Davies, M Schepelmann, D Riccardi
British Journal of Nutrition 111 (S1), S16-S22, 2014
642014
The extracellular calcium-sensing receptor regulates human fetal lung development via CFTR
SC Brennan, WJ Wilkinson, HE Tseng, B Finney, B Monk, H Dibble, ...
Scientific reports 6 (1), 21975, 2016
592016
Treatment of autosomal dominant hypocalcemia type 1 with the calcilytic NPSP795 (SHP635)
MS Roberts, RI Gafni, B Brillante, LC Guthrie, J Streit, D Gash, J Gelb, ...
Journal of Bone and Mineral Research 34 (9), 1609-1618, 2019
472019
The extracellular calcium-sensing receptor, CaSR, in fetal development
D Riccardi, SC Brennan, W Chang
Best practice & research Clinical endocrinology & metabolism 27 (3), 443-453, 2013
462013
Fetal calcium regulates branching morphogenesis in the developing human and mouse lung: involvement of voltage-gated calcium channels
SC Brennan, BA Finney, M Lazarou, AE Rosser, C Scherf, D Adriaensen, ...
PloS one 8 (11), e80294, 2013
432013
A novel mutation of the primary protein kinase C phosphorylation site in the calcium-sensing receptor causes autosomal dominant hypocalcemia
S Lazarus, CJ Pretorius, F Khafagi, KL Campion, SC Brennan, ...
European journal of endocrinology 164 (3), 429-435, 2011
372011
Receptor Expression Modulates Calcium-Sensing Receptor Mediated Intracellular Ca2+ Mobilization
SC Brennan, HC Mun, K Leach, PW Kuchel, A Christopoulos, ...
Endocrinology 156 (4), 1330-1342, 2015
342015
The calcium‐sensing receptor: one of a kind
I Lopez‐Fernandez, M Schepelmann, SC Brennan, PL Yarova, D Riccardi
Experimental physiology 100 (12), 1392-1399, 2015
322015
Homer1 mediates CaSR-dependent activation of mTOR complex 2 and initiates a novel pathway for AKT-dependent β-catenin stabilization in osteoblasts
MS Rybchyn, KS Islam, TC Brennan-Speranza, Z Cheng, SC Brennan, ...
Journal of Biological Chemistry 294 (44), 16337-16350, 2019
282019
Allosteric agonists of the calcium receptor (CaR): fluorine and SF 5 analogues of cinacalcet
PW Chia, SC Brennan, AMZ Slawin, D Riccardi, D O'Hagan
Organic & biomolecular chemistry 10 (39), 7922-7927, 2012
282012
Effectors of the frequency of calcium oscillations in HEK-293 cells: wavelet analysis and a computer model
D Szekely, SC Brennan, HC Mun, AD Conigrave, PW Kuchel
European Biophysics Journal 39, 149-165, 2009
172009
Adenomatous Human Parathyroid Cells Exhibit Impaired Sensitivity to l-Amino Acids
HC Mun, SC Brennan, L Delbridge, M Wilkinson, EM Brown, ...
The Journal of Clinical Endocrinology & Metabolism 94 (9), 3567-3574, 2009
162009
Impaired mineral ion metabolism in a mouse model of targeted calcium-sensing receptor (CaSR) deletion from vascular smooth muscle cells
M Schepelmann, M Ranieri, I Lopez-Fernandez, TS Webberley, ...
Journal of the American Society of Nephrology 33 (7), 1323-1340, 2022
152022
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