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Daniel M Cohen
Daniel M Cohen
Spark Therapeutics
Email confirmado em Sparktx.com
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Control of stem cell fate by physical interactions with the extracellular matrix
F Guilak, DM Cohen, BT Estes, JM Gimble, W Liedtke, CS Chen
Cell stem cell 5 (1), 17-26, 2009
22622009
Rapid casting of patterned vascular networks for perfusable engineered three-dimensional tissues
JS Miller, KR Stevens, MT Yang, BM Baker, DHT Nguyen, DM Cohen, ...
Nature materials 11 (9), 768-774, 2012
21832012
Degradation-mediated cellular traction directs stem cell fate in covalently crosslinked three-dimensional hydrogels
S Khetan, M Guvendiren, WR Legant, DM Cohen, CS Chen, JA Burdick
Nature materials, 2013
12942013
Mechanical tugging force regulates the size of cell–cell junctions
Z Liu, JL Tan, DM Cohen, MT Yang, NJ Sniadecki, SA Ruiz, CM Nelson, ...
Proceedings of the National Academy of Sciences 107 (22), 9944-9949, 2010
8602010
Measurement of mechanical tractions exerted by cells in three-dimensional matrices
WR Legant, JS Miller, BL Blakely, DM Cohen, GM Genin, CS Chen
Nature methods 7 (12), 969-971, 2010
7662010
Structural basis for vinculin activation at sites of cell adhesion
C Bakolitsa, DM Cohen, LA Bankston, AA Bobkov, GW Cadwell, ...
Nature 430 (6999), 583-586, 2004
4632004
Fluid shear stress threshold regulates angiogenic sprouting
PA Galie, DHT Nguyen, CK Choi, DM Cohen, PA Janmey, CS Chen
Proceedings of the National Academy of Sciences 111 (22), 7968-7973, 2014
4462014
Cytoskeleton-based forecasting of stem cell lineage fates
MD Treiser, EH Yang, S Gordonov, DM Cohen, IP Androulakis, J Kohn, ...
Proceedings of the National Academy of Sciences 107 (2), 610-615, 2010
3322010
IgG-cleaving endopeptidase enables in vivo gene therapy in the presence of anti-AAV neutralizing antibodies
C Leborgne, E Barbon, JM Alexander, H Hanby, S Delignat, DM Cohen, ...
Nature Medicine, 1-6, 2020
2762020
Bone morphogenetic protein-2-induced signaling and osteogenesis is regulated by cell shape, RhoA/ROCK, and cytoskeletal tension
YK Wang, X Yu, DM Cohen, MA Wozniak, MT Yang, L Gao, J Eyckmans, ...
Stem cells and development 21 (7), 1176-1186, 2011
2762011
Spatial distribution and functional significance of activated vinculin in living cells
H Chen, DM Cohen, DM Choudhury, N Kioka, SW Craig
The Journal of cell biology 169 (3), 459-470, 2005
2312005
Two distinct head-tail interfaces cooperate to suppress activation of vinculin by talin
DM Cohen, H Chen, RP Johnson, B Choudhury, SW Craig
Journal of Biological Chemistry 280 (17), 17109-17117, 2005
1992005
A conformational switch in vinculin drives formation and dynamics of a talin-vinculin complex at focal adhesions
DM Cohen, B Kutscher, H Chen, DB Murphy, SW Craig
Journal of Biological Chemistry 281 (23), 16006-16015, 2006
1982006
Buried charged surface in proteins
GA Kajander T, Kahn PC, Passila SH, Cohen DC, Lehtiö L, Adolfsen W ...
Structure 8 (11), 1203-14, 2000
1512000
Adrian Goldman. 2000. Buried Charged Surface Proteins
T Kajander, SHP PCK, CC Daniel, WA Lari Lehito, US Jim Warwicker
Structure 8, 1203-1214, 0
151*
Tribbles-1 regulates hepatic lipogenesis through posttranscriptional regulation of C/EBPα
RC Bauer, M Sasaki, DM Cohen, J Cui, MA Smith, BO Yenilmez, ...
The Journal of clinical investigation 125 (10), 3809-3818, 2015
982015
Activation of beta 1 but not beta 3 integrin increases cell traction forces
GL Lin, DM Cohen, RA Desai, MT Breckenridge, L Gao, MJ Humphries, ...
FEBS letters 587 (6), 763-769, 2013
902013
Control of surface chemistry, substrate stiffness, and cell function in a novel terpolymer methacrylate library
A Joy, DM Cohen, A Luk, E Anim-Danso, C Chen, J Kohn
Langmuir 27 (5), 1891-1899, 2011
872011
Mechanical control of stem cell differentiation
DM Cohen, CS Chen
Harvard Stem Cell Institute, 2008
642008
ATF4 licenses C/EBPβ activity in human mesenchymal stem cells primed for adipogenesis.
DM Cohen, W Kyoung-Jae, N Nha, MA Lazar, CS Chen, DJ Steger
Elife, 2015
592015
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Artigos 1–20