Mechanical stress conditioning and electrical stimulation promote contractility and force maturation of induced pluripotent stem cell-derived human cardiac tissue JL Ruan, NL Tulloch, MV Razumova, M Saiget, V Muskheli, L Pabon, ... Circulation 134 (20), 1557-1567, 2016 | 485 | 2016 |
Mechanical stress promotes maturation of human myocardium from pluripotent stem cell-derived progenitors JL Ruan, NL Tulloch, M Saiget, SL Paige, MV Razumova, M Regnier, ... Stem cells 33 (7), 2148-2157, 2015 | 162 | 2015 |
Irradiation at ultra-high (FLASH) dose rates reduces acute normal tissue toxicity in the mouse gastrointestinal system JL Ruan, C Lee, S Wouters, IDC Tullis, M Verslegers, M Mysara, CK Then, ... International Journal of Radiation Oncology* Biology* Physics 111 (5), 1250-1261, 2021 | 106 | 2021 |
An improved cryosection method for polyethylene glycol hydrogels used in tissue engineering JL Ruan, NL Tulloch, V Muskheli, EE Genova, PD Mariner, KS Anseth, ... Tissue Engineering Part C: Methods 19 (10), 794-801, 2013 | 59 | 2013 |
Radiosensitization In Vivo by Histone Deacetylase Inhibition with No Increase in Early Normal Tissue Radiation Toxicity B Groselj, JL Ruan, H Scott, J Gorrill, J Nicholson, J Kelly, S Anbalagan, ... Molecular cancer therapeutics 17 (2), 381-392, 2018 | 47 | 2018 |
Effects of ultrasound-induced inertial cavitation on enzymatic thrombolysis YH Chuang, PW Cheng, SC Chen, JL Ruan, PC Li Ultrasonic imaging 32 (2), 81-90, 2010 | 39 | 2010 |
In vitro assays for investigating the FLASH effect G Adrian, JL Ruan, S Paillas, CR Cooper, K Petersson Expert Reviews in Molecular Medicine 24, e10, 2022 | 33 | 2022 |
Combining sonodynamic therapy with chemoradiation for the treatment of pancreatic cancer RJ Browning, S Able, JL Ruan, L Bau, PD Allen, V Kersemans, ... Journal of Controlled Release 337, 371-377, 2021 | 31 | 2021 |
The histone deacetylase inhibitor romidepsin spares normal tissues while acting as an effective radiosensitizer in bladder tumors in vivo S Paillas, CK Then, S Kilgas, JL Ruan, J Thompson, A Elliott, S Smart, ... International Journal of Radiation Oncology* Biology* Physics 107 (1), 212-221, 2020 | 26 | 2020 |
In Vitro Evaluation of Ultrasound-Assisted Thrombolysis Using a Targeted Ultrasound Contrast Agent SC Chen, JL Ruan, PW Cheng, YH Chuang, PC Li Ultrasonic imaging 31 (4), 235-246, 2009 | 18 | 2009 |
Ultrasound-mediated gemcitabine delivery reduces the normal-tissue toxicity of chemoradiation therapy in a muscle-invasive bladder cancer model JL Ruan, RJ Browning, YO Yildiz, M Gray, L Bau, S Kamila, J Thompson, ... International Journal of Radiation Oncology* Biology* Physics 109 (5), 1472-1482, 2021 | 14 | 2021 |
Mouse models of muscle-invasive bladder cancer: key considerations for clinical translation based on molecular subtypes JL Ruan, JW Hsu, RJ Browning, E Stride, YO Yildiz, B Vojnovic, AE Kiltie European Urology Oncology 2 (3), 239-247, 2019 | 13 | 2019 |
Evaluation of loading strategies to improve tumor uptake of gemcitabine in a murine orthotopic bladder cancer model using ultrasound and microbubbles JL Ruan, RJ Browning, YO Yildiz, L Bau, S Kamila, MD Gray, L Folkes, ... Ultrasound in Medicine & Biology 47 (6), 1596-1615, 2021 | 9 | 2021 |
Ultrasound generated mechanical induction of mesenchymal stem cells JL Ruan, YN Wang, LA Crum, SB Mitchell 2010 IEEE International Ultrasonics Symposium, 1763-1766, 2010 | 7 | 2010 |
The AsiDNA™ decoy mimicking DSBs protects the normal tissue from radiation toxicity through a DNA-PK/p53/p21-dependent G1/S arrest A Sesink, M Becerra, JL Ruan, S Leboucher, M Dubail, S Heinrich, ... NAR cancer 6 (1), zcae011, 2024 | 3 | 2024 |
Targeted opening of the blood-brain barrier using VCAM-1 functionalised microbubbles and “whole brain” ultrasound VA Johanssen, JL Ruan, O Vince, A Thomas, S Peeters, MS Soto, J Buck, ... Theranostics 14 (10), 4076, 2024 | 2 | 2024 |
Investigation of the ultrasound-mediated toxicity mechanisms of various sonosensitive drugs K Singh, A Vasilyeva, L Hu, JL Ruan, M Gray, EP Stride The Journal of the Acoustical Society of America 153 (3_supplement), A33-A33, 2023 | 2 | 2023 |
OC-0581: FLEPAC: A FLASH therapy treatment planning system for electrons, protons, Helium and Carbon ions. F Van den Heuvel, J Ruan, F Fiorini, A Vella, M Brooke, A Kiltie, A Ryan, ... Radiotherapy and Oncology 152, S326-S327, 2020 | 1 | 2020 |
Effect of low intensity pulsed ultrasound on mesenchymal stem cells. JL Ruan, YN Wang, LA Crum, SB Mitchell The Journal of the Acoustical Society of America 129 (4_Supplement), 2576-2576, 2011 | 1 | 2011 |
Breaking barriers: we need a multidisciplinary approach to tackle cancer drug resistance J Ingham, JL Ruan, MA Coelho BJC reports 3 (1), 11, 2025 | | 2025 |