| Proposed minimum reporting standards for chemical analysis: chemical analysis working group (CAWG) metabolomics standards initiative (MSI) LW Sumner, A Amberg, D Barrett, MH Beale, R Beger, CA Daykin, ... Metabolomics 3, 211-221, 2007 | 4652 | 2007 |
| Procedures for large-scale metabolic profiling of serum and plasma using gas chromatography and liquid chromatography coupled to mass spectrometry WB Dunn, D Broadhurst, P Begley, E Zelena, S Francis-McIntyre, ... Nature protocols 6 (7), 1060-1083, 2011 | 2867 | 2011 |
| Integrated metabonomic analysis of the multiorgan effects of hydrazine toxicity in the rat S Garrod, ME Bollard, AW Nicholls, SC Connor, J Connelly, JK Nicholson, ... Chemical research in toxicology 18 (2), 115-122, 2005 | 558 | 2005 |
| The importance of experimental design and QC samples in large-scale and MS-driven untargeted metabolomic studies of humans WB Dunn, ID Wilson, AW Nicholls, D Broadhurst Bioanalysis 4 (18), 2249-2264, 2012 | 516 | 2012 |
| Chemometric models for toxicity classification based on NMR spectra of biofluids E Holmes, AW Nicholls, JC Lindon, SC Connor, JC Connelly, ... Chemical research in toxicology 13 (6), 471-478, 2000 | 395 | 2000 |
| Novel gut-based pharmacology of metformin in patients with type 2 diabetes mellitus A Napolitano, S Miller, AW Nicholls, D Baker, S Van Horn, E Thomas, ... PloS one 9 (7), e100778, 2014 | 355 | 2014 |
| Nuclear magnetic resonance spectroscopic and principal components analysis investigations into biochemical effects of three model hepatotoxins BM Beckwith-Hall, JK Nicholson, AW Nicholls, PJD Foxall, JC Lindon, ... Chemical research in toxicology 11 (4), 260-272, 1998 | 348 | 1998 |
| Development of a model for classification of toxin‐induced lesions using 1H NMR spectroscopy of urine combined with pattern recognition E Holmes, AW Nicholls, JC Lindon, S Ramos, M Spraul, P Neidig, ... NMR in Biomedicine 11 (4‐5), 235-244, 1998 | 308 | 1998 |
| NMR spectroscopic-based metabonomic studies of urinary metabolite variation in acclimatizing germ-free rats AW Nicholls, RJ Mortishire-Smith, JK Nicholson Chemical research in toxicology 16 (11), 1395-1404, 2003 | 280 | 2003 |
| Molecular phenotyping of a UK population: defining the human serum metabolome WB Dunn, W Lin, D Broadhurst, P Begley, M Brown, E Zelena, ... Metabolomics 11, 9-26, 2015 | 256 | 2015 |
| Metabonomic investigations into hydrazine toxicity in the rat AW Nicholls, E Holmes, JC Lindon, JP Shockcor, RD Farrant, ... Chemical research in toxicology 14 (8), 975-987, 2001 | 249 | 2001 |
| The identification of novel biomarkers of renal toxicity using automatic data reduction techniques and PCA of proton NMR spectra of urine E Holmes, JK Nicholson, AW Nicholls, JC Lindon, SC Connor, S Polley, ... Chemometrics and Intelligent Laboratory Systems 44 (1-2), 245-255, 1998 | 232 | 1998 |
| Use of metabonomics to identify impaired fatty acid metabolism as the mechanism of a drug-induced toxicity RJ Mortishire-Smith, GL Skiles, JW Lawrence, S Spence, AW Nicholls, ... Chemical research in toxicology 17 (2), 165-173, 2004 | 180 | 2004 |
| Comparative metabonomics of differential hydrazine toxicity in the rat and mouse ME Bollard, HC Keun, O Beckonert, TMD Ebbels, H Antti, AW Nicholls, ... Toxicology and Applied Pharmacology 204 (2), 135-151, 2005 | 174 | 2005 |
| Metabolomics as a functional genomic tool for understanding lipid dysfunction in diabetes, obesity and related disorders JL Griffin, AW Nicholls Pharmacogenomics 7 (7), 1095-1107, 2006 | 161 | 2006 |
| A metabonomic approach to the investigation of drug-induced phospholipidosis: an NMR spectroscopy and pattern recognition study AW Nicholls, JK Nicholson, JN Haselden, CJ Waterfield Biomarkers 5 (6), 410-423, 2000 | 131 | 2000 |
| The contrasting roles of PPARδ and PPARγ in regulating the metabolic switch between oxidation and storage of fats in white adipose tissue LD Roberts, AJ Murray, D Menassa, T Ashmore, AW Nicholls, JL Griffin Genome Biology 12 (8), R75, 2011 | 126 | 2011 |
| Automatic alignment of individual peaks in large high-resolution spectral data sets R Stoyanova, AW Nicholls, JK Nicholson, JC Lindon, TR Brown Journal of Magnetic Resonance 170 (2), 329-335, 2004 | 120 | 2004 |
| Metabolic phenotyping of a model of adipocyte differentiation LD Roberts, S Virtue, A Vidal-Puig, AW Nicholls, JL Griffin Physiological genomics 39 (2), 109-119, 2009 | 117 | 2009 |
| Genome-Wide Association Study of Metabolic Traits Reveals Novel Gene-Metabolite-Disease Links R Rueedi, M Ledda, AW Nicholls, et al PLoS Genetics 10 (2), e1004132, 2014 | 104 | 2014 |
Jeremy K NicholsonAustralian National Phenome Center, Murdoch University + Imperial College LondonEmail confirmado em murdoch.edu.au
