MicroRNA-29 family reverts aberrant methylation in lung cancer by targeting DNA methyltransferases 3A and 3B M Fabbri, R Garzon, A Cimmino, Z Liu, N Zanesi, E Callegari, S Liu, ... Proceedings of the National Academy of Sciences 104 (40), 15805-15810, 2007 | 2049 | 2007 |
MicroRNA-29b induces global DNA hypomethylation and tumor suppressor gene reexpression in acute myeloid leukemia by targeting directly DNMT3A and 3B and indirectly … R Garzon, S Liu, M Fabbri, Z Liu, CEA Heaphy, E Callegari, S Schwind, ... Blood, The Journal of the American Society of Hematology 113 (25), 6411-6418, 2009 | 938 | 2009 |
Phase I trial of the histone deacetylase inhibitor, depsipeptide (FR901228, NSC 630176), in patients with refractory neoplasms V Sandor, S Bakke, RW Robey, MH Kang, MV Blagosklonny, J Bender, ... Clinical Cancer Research 8 (3), 718-728, 2002 | 689 | 2002 |
Clinical response and miR-29b predictive significance in older AML patients treated with a 10-day schedule of decitabine W Blum, R Garzon, RB Klisovic, S Schwind, A Walker, S Geyer, S Liu, ... Proceedings of the National Academy of Sciences 107 (16), 7473-7478, 2010 | 609 | 2010 |
A phase 1 and pharmacodynamic study of depsipeptide (FK228) in chronic lymphocytic leukemia and acute myeloid leukemia JC Byrd, G Marcucci, MR Parthun, JJ Xiao, RB Klisovic, M Moran, TS Lin, ... Blood 105 (3), 959-967, 2005 | 490 | 2005 |
Recent developments in the maytansinoid antitumor agents JM Cassady, KK Chan, HG Floss, E Leistner Chemical and Pharmaceutical Bulletin 52 (1), 1-26, 2004 | 422 | 2004 |
Curcumin is a potent DNA hypomethylation agent Z Liu, Z Xie, W Jones, RE Pavlovicz, S Liu, J Yu, P Li, J Lin, JR Fuchs, ... Bioorganic & medicinal chemistry letters 19 (3), 706-709, 2009 | 396 | 2009 |
Phase I study of decitabine alone or in combination with valproic acid in acute myeloid leukemia W Blum, RB Klisovic, B Hackanson, Z Liu, S Liu, H Devine, ... Journal of Clinical Oncology 25 (25), 3884-3891, 2007 | 384 | 2007 |
Blocking telomerase by dietary polyphenols is a major mechanism for limiting the growth of human cancer cells in vitro and in vivo I Naasani, F Oh-Hashi, T Oh-Hara, WY Feng, J Johnston, K Chan, ... Cancer research 63 (4), 824-830, 2003 | 336 | 2003 |
Warfarin stereochemical aspects of its metabolism and the interaction with phenylbutazone RJ Lewis, WF Trager, KK Chan, A Breckenridge, M Orme, M Roland, ... The Journal of Clinical Investigation 53 (6), 1607-1617, 1974 | 334 | 1974 |
Phase 1 and pharmacodynamic studies of G3139, a Bcl-2 antisense oligonucleotide, in combination with chemotherapy in refractory or relapsed acute leukemia G Marcucci, JC Byrd, G Dai, MI Klisovic, PJ Kourlas, DC Young, ... Blood, The Journal of the American Society of Hematology 101 (2), 425-432, 2003 | 320 | 2003 |
Sp1/NFκB/HDAC/miR-29b regulatory network in KIT-driven myeloid leukemia S Liu, LC Wu, J Pang, R Santhanam, S Schwind, YZ Wu, CJ Hickey, J Yu, ... Cancer cell 17 (4), 333-347, 2010 | 304 | 2010 |
Cardiotoxicity of histone deacetylase inhibitor depsipeptide in patients with metastatic neuroendocrine tumors MH Shah, P Binkley, K Chan, J Xiao, D Arbogast, M Collamore, Y Farra, ... Clinical Cancer Research 12 (13), 3997-4003, 2006 | 274 | 2006 |
Targeted Delivery of microRNA-29b by Transferrin-Conjugated Anionic Lipopolyplex Nanoparticles: A Novel Therapeutic Strategy in Acute Myeloid Leukemia X Huang, S Schwind, B Yu, R Santhanam, H Wang, P Hoellerbauer, ... Clinical Cancer Research 19 (9), 2355-2367, 2013 | 223 | 2013 |
Aberrant overexpression of IL-15 initiates large granular lymphocyte leukemia through chromosomal instability and DNA hypermethylation A Mishra, S Liu, GH Sams, DP Curphey, R Santhanam, LJ Rush, ... Cancer cell 22 (5), 645-655, 2012 | 216 | 2012 |
Enhancement of curcumin oral absorption and pharmacokinetics of curcuminoids and curcumin metabolites in mice L Zhongfa, M Chiu, J Wang, W Chen, W Yen, P Fan-Havard, LD Yee, ... Cancer chemotherapy and pharmacology 69, 679-689, 2012 | 199 | 2012 |
Acetylator phenotype, aminobiphenyl-hemoglobin adduct levels, and bladder cancer risk in white, black, and Asian men in Los Angeles, California MC Yu, PL Skipper, K Taghizadeh, SR Tannenbaum, KK Chan, ... JNCI: Journal of the National Cancer Institute 86 (9), 712-716, 1994 | 194 | 1994 |
Depsipeptide (FR 901228) promotes histone acetylation, gene transcription, apoptosis and its activity is enhanced by DNA methyltransferase inhibitors in AML1/ETO-positive … MI Klisovic, EA Maghraby, MR Parthun, M Guimond, AR Sklenar, ... Leukemia 17 (2), 350-358, 2003 | 187 | 2003 |
Arylamine exposures and bladder cancer risk CY Mimi, PL Skipper, SR Tannenbaum, KK Chan, RK Ross Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 506, 21-28, 2002 | 186 | 2002 |
Phase I study of oblimersen sodium, an antisense to Bcl-2, in untreated older patients with acute myeloid leukemia: pharmacokinetics, pharmacodynamics, and clinical activity G Marcucci, W Stock, G Dai, RB Klisovic, S Liu, MI Klisovic, W Blum, ... Journal of clinical oncology 23 (15), 3404-3411, 2005 | 184 | 2005 |