| A mechanistic link between an inherited and an acquird cardiac arrthytmia: HERG encodes the IKr potassium channel MC Sanguinetti, C Jiang, ME Curran, MT Keating Cell 81 (2), 299-307, 1995 | 2915 | 1995 |
| Coassembly of KvLQT1 and minK (IsK) proteins to form cardiac IKs potassium channel MC Sanguinetti, ME Curran, A Zou, J Shen, PS Spector, DL Atkinson, ... Nature 384, 1996 | 2166 | 1996 |
| Two components of cardiac delayed rectifier K+ current. Differential sensitivity to block by class III antiarrhythmic agents. MC Sanguinetti, NK Jurkiewicz Journal of General Physiology 96 (1), 195-215, 1990 | 1982* | 1990 |
| CaV1. 2 calcium channel dysfunction causes a multisystem disorder including arrhythmia and autism I Splawski, KW Timothy, LM Sharpe, N Decher, P Kumar, R Bloise, ... Cell 119 (1), 19-31, 2004 | 1932 | 2004 |
| hERG potassium channels and cardiac arrhythmia MC Sanguinetti, M Tristani-Firouzi Nature 440 (7083), 463-469, 2006 | 1855 | 2006 |
| International Union of Pharmacology. LIII. Nomenclature and molecular relationships of voltage-gated potassium channels GA Gutman, KG Chandy, S Grissmer, M Lazdunski, D Mckinnon, ... Pharmacological reviews 57 (4), 473-508, 2005 | 1294 | 2005 |
| Molecular and cellular mechanisms of cardiac arrhythmias MT Keating, MC Sanguinetti Cell 104 (4), 569-580, 2001 | 1288 | 2001 |
| Loss-of-function mutations in the cardiac calcium channel underlie a new clinical entity characterized by ST-segment elevation, short QT intervals, and sudden cardiac death C Antzelevitch, GD Pollevick, JM Cordeiro, O Casis, MC Sanguinetti, ... Circulation 115 (4), 442-449, 2007 | 1219 | 2007 |
| A structural basis for drug-induced long QT syndrome JS Mitcheson, J Chen, M Lin, C Culberson, MC Sanguinetti Proceedings of the National Academy of Sciences 97 (22), 12329-12333, 2000 | 1150 | 2000 |
| Mutations in the hminK gene cause long QT syndrome and suppress lKs function I Splawski, M Tristani-Firouzi, MH Lehmann, MC Sanguinetti, MT Keating Nature genetics 17 (3), 338-340, 1997 | 999 | 1997 |
| Severe arrhythmia disorder caused by cardiac L-type calcium channel mutations I Splawski, KW Timothy, N Decher, P Kumar, FB Sachse, AH Beggs, ... Proceedings of the National Academy of Sciences 102 (23), 8089-8096, 2005 | 784 | 2005 |
| Voltage-dependent block of calcium channel current in the calf cardiac Purkinje fiber by dihydropyridine calcium channel antagonists. MC Sanguinetti, RS Kass Circulation research 55 (3), 336-348, 1984 | 671 | 1984 |
| Rate-dependent prolongation of cardiac action potentials by a methanesulfonanilide class III antiarrhythmic agent. Specific block of rapidly activating delayed rectifier K+ … NK Jurkiewicz, MC Sanguinetti Circulation research 72 (1), 75-83, 1993 | 659 | 1993 |
| Spectrum of HERG K+-channel dysfunction in an inherited cardiac arrhythmia. MC Sanguinetti, ME Curran, PS Spector, MT Keating Proceedings of the National Academy of Sciences 93 (5), 2208-2212, 1996 | 586 | 1996 |
| Molecular medical microbiology YW Tang, M Hindiyeh, D Liu, A Sails, P Spearman, JR Zhang Academic press, 2023 | 556 | 2023 |
| Fast inactivation causes rectification of the IKr channel. PS Spector, ME Curran, A Zou, MT Keating, MC Sanguinetti The Journal of general physiology 107 (5), 611-619, 1996 | 530 | 1996 |
| International Union of Pharmacology. XLI. Compendium of voltage-gated ion channels: potassium channels GA Gutman, KG Chandy, JP Adelman, J Aiyar, DA Bayliss, DE Clapham, ... Pharmacological reviews 55 (4), 583-586, 2003 | 474 | 2003 |
| Drug‐induced torsades de pointes and implications for drug development RR Fenichel, M Malik, C Antzelevitch, M Sanguinetti, DM Roden, ... Journal of cardiovascular electrophysiology 15 (4), 475-495, 2004 | 434 | 2004 |
| Genetically defined therapy of inherited long-QT syndrome: correction of abnormal repolarization by potassium SJ Compton, RL Lux, MR Ramsey, KR Strelich, MC Sanguinetti, LS Green, ... Circulation 94 (5), 1018-1022, 1996 | 428 | 1996 |
| De novo KCNQ1 mutation responsible for atrial fibrillation and short QT syndrome in utero K Hong, DR Piper, A Diaz-Valdecantos, J Brugada, A Oliva, ... Cardiovascular research 68 (3), 433-440, 2005 | 388 | 2005 |
Mark CurranJanssen R&D LLCEmail confirmado em its.jnj.com