| Interaction of tau with the neural plasma membrane mediated by tau's amino-terminal projection domain. R Brandt, J Léger, G Lee Journal of Cell Biology 131 (5), 1327-1340, 1995 | 870 | 1995 |
| CD95 ligand (Fas-L/APO-1L) and tumor necrosis factor-related apoptosis-inducing ligand mediate ischemia-induced apoptosis in neurons A Martin-Villalba, I Herr, I Jeremias, M Hahne, R Brandt, J Vogel, ... Journal of Neuroscience 19 (10), 3809-3817, 1999 | 614 | 1999 |
| Molecular interactions among protein phosphatase 2A, tau, and microtubules: implications for the regulation of tau phosphorylation and the development of tauopathies E Sontag, V Nunbhakdi-Craig, G Lee, R Brandt, C Kamibayashi, J Kuret, ... Journal of Biological Chemistry 274 (36), 25490-25498, 1999 | 407 | 1999 |
| Tau alteration and neuronal degeneration in tauopathies: mechanisms and models R Brandt, M Hundelt, N Shahani Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1739 (2-3 …, 2005 | 338 | 2005 |
| Process outgrowth of oligodendrocytes is promoted by interaction of fyn kinase with the cytoskeletal protein tau C Klein, EM Krämer, AM Cardine, B Schraven, R Brandt, J Trotter Journal of Neuroscience 22 (3), 698-707, 2002 | 336 | 2002 |
| Tau binds to the distal axon early in development of polarity in a microtubule-and microfilament-dependent manner M Kempf, A Clement, A Faissner, G Lee, R Brandt Journal of Neuroscience 16 (18), 5583-5592, 1996 | 329 | 1996 |
| Functional organization of microtubule-associated protein tau. Identification of regions which affect microtubule growth, nucleation, and bundle formation in vitro. R Brandt, G Lee Journal of Biological Chemistry 268 (5), 3414-3419, 1993 | 320 | 1993 |
| Tau-mediated cytotoxicity in a pseudohyperphosphorylation model of Alzheimer's disease T Fath, J Eidenmüller, R Brandt Journal of Neuroscience 22 (22), 9733-9741, 2002 | 299 | 2002 |
| Interaction of tau with the neural membrane cortex is regulated by phosphorylation at sites that are modified in paired helical filaments T Maas, J Eidenmüller, R Brandt Journal of Biological Chemistry 275 (21), 15733-15740, 2000 | 291 | 2000 |
| Functions and malfunctions of the tau proteins N Shahani, R Brandt Cellular and Molecular Life Sciences CMLS 59, 1668-1680, 2002 | 257 | 2002 |
| Tau biology and tau-directed therapies for Alzheimer’s disease L Bakota, R Brandt Drugs 76 (3), 301-313, 2016 | 215 | 2016 |
| Single-molecule tracking of tau reveals fast kiss-and-hop interaction with microtubules in living neurons D Janning, M Igaev, F Sündermann, J Brühmann, O Beutel, JJ Heinisch, ... Molecular biology of the cell 25 (22), 3541-3551, 2014 | 195 | 2014 |
| Divergent pathways mediate spine alterations and cell death induced by amyloid-β, wild-type tau, and R406W tau C Tackenberg, R Brandt Journal of Neuroscience 29 (46), 14439-14450, 2009 | 174 | 2009 |
| Phosphorylation-mimicking glutamate clusters in the proline-rich region are sufficient to simulate the functional deficiencies of hyperphosphorylated tau protein J Eidenmüller, T Fath, T Maas, M Pool, E Sontag, R Brandt Biochemical Journal 357 (3), 759-767, 2001 | 172 | 2001 |
| Conversion of serine to aspartate imitates phosphorylation-induced changes in the structure and function of microtubule-associated protein tau J Léger, M Kempf, G Lee, R Brandt Journal of Biological Chemistry 272 (13), 8441-8446, 1997 | 169 | 1997 |
| The frontotemporal dementia mutation R406W blocks tau’s interaction with the membrane in an annexin A2–dependent manner A Gauthier-Kemper, C Weissmann, N Golovyashkina, Z Sebö-Lemke, ... Journal of Cell Biology 192 (4), 647-661, 2011 | 159 | 2011 |
| A Caenorhabditis elegans model of tau hyperphosphorylation: induction of developmental defects by transgenic overexpression of Alzheimer's disease-like modified tau R Brandt, A Gergou, I Wacker, T Fath, H Hutter Neurobiology of aging 30 (1), 22-33, 2009 | 151 | 2009 |
| NMDA receptor subunit composition determines beta-amyloid-induced neurodegeneration and synaptic loss C Tackenberg, S Grinschgl, A Trutzel, AC Santuccione, MC Frey, ... Cell death & disease 4 (4), e608-e608, 2013 | 150 | 2013 |
| Structural and functional implications of tau hyperphosphorylation: information from phosphorylation-mimicking mutated tau proteins J Eidenmüller, T Fath, A Hellwig, J Reed, E Sontag, R Brandt Biochemistry 39 (43), 13166-13175, 2000 | 149 | 2000 |
| Differential effect of phosphorylation and substrate modulation on tau's ability to promote microtubule growth and nucleation. R Brandt, G Lee, DB Teplow, D Shalloway, M Abdel-Ghany Journal of Biological Chemistry 269 (16), 11776-11782, 1994 | 136 | 1994 |
Gloria LeeUniversity of IowaEmail confirmado em uiowa.edu
