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Ann Marie Woys
Ann Marie Woys
Genentech
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Two-dimensional infrared spectroscopy reveals the complex behaviour of an amyloid fibril inhibitor
CT Middleton, P Marek, P Cao, C Chiu, S Singh, AM Woys, JJ De Pablo, ...
Nature chemistry 4 (5), 355-360, 2012
2042012
Residue-specific structural kinetics of proteins through the union of isotope labeling, mid-IR pulse shaping, and coherent 2D IR spectroscopy
CT Middleton, AM Woys, SS Mukherjee, MT Zanni
Methods 52 (1), 12-22, 2010
1612010
Two-dimensional IR spectroscopy and segmental 13C labeling reveals the domain structure of human γD-crystallin amyloid fibrils
SD Moran, AM Woys, LE Buchanan, E Bixby, SM Decatur, MT Zanni
Proceedings of the National Academy of Sciences 109 (9), 3329-3334, 2012
1582012
2DIR spectroscopy of human amylin fibrils reflects stable β-sheet structure
L Wang, CT Middleton, S Singh, AS Reddy, AM Woys, DB Strasfeld, ...
Journal of the American Chemical Society 133 (40), 16062-16071, 2011
1392011
2D IR line shapes probe ovispirin peptide conformation and depth in lipid bilayers
AM Woys, YS Lin, AS Reddy, W Xiong, JJ de Pablo, JL Skinner, MT Zanni
Journal of the American Chemical Society 132 (8), 2832-2838, 2010
1192010
Parallel β-sheet vibrational couplings revealed by 2D IR spectroscopy of an isotopically labeled macrocycle: quantitative benchmark for the interpretation of amyloid and …
AM Woys, AM Almeida, L Wang, CC Chiu, M McGovern, JJ De Pablo, ...
Journal of the American Chemical Society 134 (46), 19118-19128, 2012
1112012
Efficient microwave-assisted synthesis of human islet amyloid polypeptide designed to facilitate the specific incorporation of labeled amino acids
P Marek, AM Woys, K Sutton, MT Zanni, DP Raleigh
Organic letters 12 (21), 4848-4851, 2010
1072010
A strongly absorbing class of non-natural labels for probing protein electrostatics and solvation with FTIR and 2D IR spectroscopies
AM Woys, SS Mukherjee, DR Skoff, SD Moran, MT Zanni
The journal of physical chemistry B 117 (17), 5009-5018, 2013
582013
Adsorption of polysorbate 20 and proteins on hydrophobic polystyrene surfaces studied by neutron reflectometry
Z Zhang, S Orski, AM Woys, G Yuan, IE Zarraga, NJ Wagner, Y Liu
Colloids and Surfaces B: Biointerfaces 168, 94-102, 2018
372018
General strategy for the bioorthogonal incorporation of strongly absorbing, solvation-sensitive infrared probes into proteins
I Peran, T Oudenhoven, AM Woys, MD Watson, TO Zhang, I Carrico, ...
The Journal of Physical Chemistry B 118 (28), 7946-7953, 2014
332014
2D IR cross peaks reveal hydrogen–deuterium exchange with single residue specificity
EB Dunkelberger, AM Woys, MT Zanni
The Journal of Physical Chemistry B 117 (49), 15297-15305, 2013
332013
Adsorption of non-ionic surfactant and monoclonal antibody on siliconized surface studied by neutron reflectometry
Z Zhang, AM Woys, K Hong, C Grapentin, TA Khan, IE Zarraga, ...
Journal of colloid and interface science 584, 429-438, 2021
312021
Multi-attribute Raman spectroscopy (MARS) for monitoring product quality attributes in formulated monoclonal antibody therapeutics
B Wei, N Woon, L Dai, R Fish, M Tai, W Handagama, A Yin, J Sun, ...
MAbs 14 (1), 2007564, 2022
232022
Ultrafast interligand electron transfer in cis-[Ru (4, 4′-dicarboxylate-2, 2′-bipyridine) 2 (NCS) 2] 4− and implications for electron injection limitations in dye sensitized …
BP Rimgard, J Föhlinger, J Petersson, M Lundberg, B Zietz, AM Woys, ...
Chemical science 9 (41), 7958-7967, 2018
212018
Predicting formulation conditions during ultrafiltration and dilution to drug substance using a donnan model with homology-model based protein charge
A Kannan, M Chinn, S Izadi, A Maier, J Dvornicky, M Fedesco, E Day, ...
Journal of Pharmaceutical Sciences 112 (3), 820-829, 2023
32023
Compendial methods: suitability verification, challenges and recommendations for proteins
WL Chung, J Yin, S Messick, M Saggu, K Tschudi, A Woys, R Rahimi, ...
PDA Journal of Pharmaceutical Science and Technology 74 (5), 581-591, 2020
22020
Random Heteropolymer Excipients Improve the Colloidal Stability of a Monoclonal Antibody for Subcutaneous Administration
KMM Messina, AM Woys
Pharmaceutical Research 40 (2), 525-536, 2023
12023
Simple method for monitoring protein secondary structure during thermal unfolding and aggregation
J Briggs, AM Woys
MJH Life Sciences, 2016
12016
Random Heteropolymer Excipients For High Protein Concentration Formulations
AM Woys, KMM Messina
US Patent App. 18/825,647, 2024
2024
Clinical formulations of anti-tigit antibodies
IC Shieh, AM Woys, KL Tschudi, RM Suhling, RS Sane, HMP Chan, ...
US Patent App. 18/749,129, 2024
2024
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