| A novel role for HMGB1 in TLR9-mediated inflammatory responses to CpG-DNA S Ivanov, AM Dragoi, X Wang, C Dallacosta, J Louten, G Musco, G Sitia, ... Blood, The Journal of the American Society of Hematology 110 (6), 1970-1981, 2007 | 616 | 2007 |
| Platelets mediate cytotoxic T lymphocyte–induced liver damage M Iannacone, G Sitia, M Isogawa, P Marchese, MG Castro, ... Nature medicine 11 (11), 1167-1169, 2005 | 445 | 2005 |
| Tumor-targeted interferon-α delivery by Tie2-expressing monocytes inhibits tumor growth and metastasis M De Palma, R Mazzieri, LS Politi, F Pucci, E Zonari, G Sitia, S Mazzoleni, ... Cancer cell 14 (4), 299-311, 2008 | 354 | 2008 |
| Antiplatelet therapy prevents hepatocellular carcinoma and improves survival in a mouse model of chronic hepatitis B G Sitia, R Aiolfi, P Di Lucia, M Mainetti, A Fiocchi, F Mingozzi, A Esposito, ... Proceedings of the National Academy of Sciences 109 (32), E2165-E2172, 2012 | 345 | 2012 |
| Immunosurveillance of the liver by intravascular effector CD8+ T cells LG Guidotti, D Inverso, L Sironi, P Di Lucia, J Fioravanti, L Ganzer, ... Cell 161 (3), 486-500, 2015 | 335 | 2015 |
| In vivo administration of lentiviral vectors triggers a type I interferon response that restricts hepatocyte gene transfer and promotes vector clearance BD Brown, G Sitia, A Annoni, E Hauben, LS Sergi, A Zingale, ... Blood 109 (7), 2797-2805, 2007 | 233 | 2007 |
| Preclinical modeling highlights the therapeutic potential of hematopoietic stem cell gene editing for correction of SCID-X1 G Schiroli, S Ferrari, A Conway, A Jacob, V Capo, L Albano, T Plati, ... Science translational medicine 9 (411), eaan0820, 2017 | 230 | 2017 |
| Treatment with HMGB1 inhibitors diminishes CTL-induced liver disease in HBV transgenic mice G Sitia, M Iannacone, S Müller, ME Bianchi, LG Guidotti Journal of Leucocyte Biology 81 (1), 100-107, 2007 | 179 | 2007 |
| High mobility group box 1 orchestrates tissue regeneration via CXCR4 M Tirone, NL Tran, C Ceriotti, A Gorzanelli, M Canepari, R Bottinelli, ... Journal of Experimental Medicine 215 (1), 303-318, 2018 | 167 | 2018 |
| MMPs are required for recruitment of antigen-nonspecific mononuclear cells into the liver by CTLs G Sitia, M Isogawa, M Iannacone, IL Campbell, FV Chisari, LG Guidotti The Journal of clinical investigation 113 (8), 1158-1167, 2004 | 166 | 2004 |
| Depletion of neutrophils blocks the recruitment of antigen-nonspecific cells into the liver without affecting the antiviral activity of hepatitis B virus-specific cytotoxic T … G Sitia, M Isogawa, K Kakimi, SF Wieland, FV Chisari, LG Guidotti Proceedings of the National Academy of Sciences 99 (21), 13717-13722, 2002 | 153 | 2002 |
| HBV pathogenesis in animal models: recent advances on the role of platelets M Iannacone, G Sitia, ZM Ruggeri, LG Guidotti Journal of hepatology 46 (4), 719-726, 2007 | 148 | 2007 |
| Platelets prevent IFN-α/β-induced lethal hemorrhage promoting CTL-dependent clearance of lymphocytic choriomeningitis virus M Iannacone, G Sitia, M Isogawa, JK Whitmire, P Marchese, FV Chisari, ... Proceedings of the National Academy of Sciences 105 (2), 629-634, 2008 | 142 | 2008 |
| Defective Th1 cytokine gene transcription in CD4+ and CD8+ T cells from Wiskott-Aldrich syndrome patients S Trifari, G Sitia, A Aiuti, S Scaramuzza, F Marangoni, LG Guidotti, ... The Journal of Immunology 177 (10), 7451-7461, 2006 | 137 | 2006 |
| Kupffer cells hasten resolution of liver immunopathology in mouse models of viral hepatitis G Sitia, M Iannacone, R Aiolfi, M Isogawa, N van Rooijen, C Scozzesi, ... PLoS pathogens 7 (6), e1002061, 2011 | 124 | 2011 |
| Replication of Hepatitis C Virus in B Lymphocytes (CD19+) G Morsica, G Tambussi, G Sitia, R Novati, A Lazzarin, L Lopalco, ... Blood, The Journal of the American Society of Hematology 94 (3), 1138-1139, 1999 | 101 | 1999 |
| Bone marrow as an alternative site for islet transplantation E Cantarelli, R Melzi, A Mercalli, V Sordi, G Ferrari, CW Lederer, E Mrak, ... Blood, The Journal of the American Society of Hematology 114 (20), 4566-4574, 2009 | 91 | 2009 |
| Nkx2-5+ islet1+ mesenchymal precursors generate distinct spleen stromal cell subsets and participate in restoring stromal network integrity L Castagnaro, E Lenti, S Maruzzelli, L Spinardi, E Migliori, D Farinello, ... Immunity 38 (4), 782-791, 2013 | 90 | 2013 |
| Anti-platelet therapy in the prevention of hepatitis B virus-associated hepatocellular carcinoma G Sitia, M Iannacone, LG Guidotti Journal of hepatology 59 (5), 1135-1138, 2013 | 89 | 2013 |
| Role of CCL2/MCP-1 in islet transplantation R Melzi, A Mercalli, V Sordi, E Cantarelli, R Nano, P Maffi, G Sitia, ... Cell Transplantation 19 (8), 1031-1046, 2010 | 88 | 2010 |
