| Impaired TFEB-mediated lysosome biogenesis and autophagy promote chronic ethanol-induced liver injury and steatosis in mice X Chao, S Wang, K Zhao, Y Li, JA Williams, T Li, H Chavan, ... Gastroenterology 155 (3), 865-879. e12, 2018 | 313 | 2018 |
| Autophagy in liver diseases: a review H Qian, X Chao, J Williams, S Fulte, T Li, L Yang, WX Ding Molecular aspects of medicine 82, 100973, 2021 | 244 | 2021 |
| Removal of acetaminophen protein adducts by autophagy protects against acetaminophen-induced liver injury in mice HM Ni, MR McGill, X Chao, K Du, JA Williams, Y Xie, H Jaeschke, ... Journal of hepatology 65 (2), 354-362, 2016 | 219 | 2016 |
| Role and mechanisms of autophagy in acetaminophen‐induced liver injury X Chao, H Wang, H Jaeschke, WX Ding Liver International 38 (8), 1363-1374, 2018 | 149 | 2018 |
| Design, synthesis and pharmacological evaluation of novel tacrine–caffeic acid hybrids as multi-targeted compounds against Alzheimer’s disease X Chao, X He, Y Yang, X Zhou, M Jin, S Liu, Z Cheng, P Liu, Y Wang, J Yu, ... Bioorganic & medicinal chemistry letters 22 (20), 6498-6502, 2012 | 126 | 2012 |
| Fasudil and its analogs: a new powerful weapon in the long war against central nervous system disorders? M Chen, A Liu, Y Ouyang, Y Huang, X Chao, R Pi Expert opinion on investigational drugs 22 (4), 537-550, 2013 | 125 | 2013 |
| Double deletion of PINK1 and Parkin impairs hepatic mitophagy and exacerbates acetaminophen-induced liver injury in mice H Wang, HM Ni, X Chao, X Ma, YA Rodriguez, H Chavan, S Wang, ... Redox biology 22, 101148, 2019 | 117 | 2019 |
| Emerging and established modes of cell death during acetaminophen-induced liver injury H Jaeschke, A Ramachandran, X Chao, WX Ding Archives of toxicology 93, 3491-3502, 2019 | 116 | 2019 |
| Tacrine-6-Ferulic Acid, a Novel Multifunctional Dimer, Inhibits Amyloid-β-Mediated Alzheimer's Disease-Associated Pathogenesis In Vitro and In Vivo R Pi, X Mao, X Chao, Z Cheng, M Liu, X Duan, M Ye, X Chen, Z Mei, P Liu, ... PloS one 7 (2), e31921, 2012 | 115 | 2012 |
| Protective effects of caffeic acid and caffeic acid phenethyl ester against acrolein-induced neurotoxicity in HT22 mouse hippocampal cells Y Huang, M Jin, R Pi, J Zhang, M Chen, Y Ouyang, A Liu, X Chao, P Liu, ... Neuroscience letters 535, 146-151, 2013 | 102 | 2013 |
| Subcutaneous adipocytes promote melanoma cell growth by activating the Akt signaling pathway HY Kwan, X Fu, B Liu, X Chao, CL Chan, H Cao, T Su, AKW Tse, ... Journal of Biological Chemistry 289 (44), 30525-30537, 2014 | 92 | 2014 |
| Acrolein induces Alzheimer's disease-like pathologies in vitro and in vivo YJ Huang, MH Jin, RB Pi, JJ Zhang, Y Ouyang, XJ Chao, MH Chen, ... Toxicology letters 217 (3), 184-191, 2013 | 90 | 2013 |
| Impaired TFEB-mediated lysosomal biogenesis promotes the development of pancreatitis in mice and is associated with human pancreatitis S Wang, HM Ni, X Chao, H Wang, B Bridges, S Kumer, T Schmitt, ... Autophagy 15 (11), 1954-1969, 2019 | 89 | 2019 |
| An FGF15/19-TFEB regulatory loop controls hepatic cholesterol and bile acid homeostasis Y Wang, S Gunewardena, F Li, DJ Matye, C Chen, X Chao, T Jung, ... Nature Communications 11 (1), 3612, 2020 | 85 | 2020 |
| The anticancer and antiobesity effects of Mediterranean diet HY Kwan, X Chao, T Su, X Fu, AKW Tse, WF Fong, ZL Yu Critical reviews in food science and nutrition 57 (1), 82-94, 2017 | 84 | 2017 |
| Autophagy and liver cancer X Chao, H Qian, S Wang, S Fulte, WX Ding Clinical and molecular hepatology 26 (4), 606, 2020 | 71 | 2020 |
| Caspase inhibition prevents tumor necrosis factor-α–induced apoptosis and promotes necrotic cell death in mouse hepatocytes in vivo and in vitro HM Ni, MR McGill, X Chao, BL Woolbright, H Jaeschke, WX Ding The American journal of pathology 186 (10), 2623-2636, 2016 | 62 | 2016 |
| Cinnamon induces browning in subcutaneous adipocytes HY Kwan, J Wu, T Su, XJ Chao, B Liu, X Fu, CL Chan, RHY Lau, AKW Tse, ... Scientific reports 7 (1), 2447, 2017 | 61 | 2017 |
| Fenofibrate ameliorates cardiac hypertrophy by activation of peroxisome proliferator-activated receptor-α partly via preventing p65-NFκB binding to NFATc4 J Zou, K Le, S Xu, J Chen, Z Liu, X Chao, B Geng, J Luo, S Zeng, J Ye, ... Molecular and Cellular Endocrinology 370 (1-2), 103-112, 2013 | 61 | 2013 |
| Receptor-interacting serine/threonine-protein kinase 3 (RIPK3)–mixed lineage kinase domain-like protein (MLKL)–mediated necroptosis contributes to ischemia-reperfusion injury … HM Ni, X Chao, J Kaseff, F Deng, S Wang, YH Shi, T Li, WX Ding, ... The American Journal of Pathology 189 (7), 1363-1374, 2019 | 60 | 2019 |
