Clonal expansion of Lgr5-positive cells from mammalian cochlea and high-purity generation of sensory hair cells WJ McLean, X Yin, L Lu, DR Lenz, D McLean, R Langer, JM Karp, ... Cell reports 18 (8), 1917-1929, 2017 | 210 | 2017 |
Distribution of the Na, K-ATPase α subunit in the rat spiral ganglion and organ of corti WJ McLean, KA Smith, E Glowatzki, SJ Pyott Journal of the Association for Research in Otolaryngology 10, 37-49, 2009 | 124 | 2009 |
BK channels mediate cholinergic inhibition of high frequency cochlear hair cells E Wersinger, WJ McLean, PA Fuchs, SJ Pyott Plos one 5 (11), e13836, 2010 | 85 | 2010 |
Distinct capacity for differentiation to inner ear cell types by progenitor cells of the cochlea and vestibular organs WJ McLean, DT McLean, RA Eatock, ASB Edge Development 143 (23), 4381-4393, 2016 | 56 | 2016 |
Improved speech intelligibility in subjects with stable sensorineural hearing loss following intratympanic dosing of FX-322 in a phase 1b study WJ McLean, AS Hinton, JTJ Herby, AN Salt, JJ Hartsock, S Wilson, ... Otology & Neurotology 42 (7), e849-e857, 2021 | 45 | 2021 |
Distribution of Na, K-ATPase α subunits in rat vestibular sensory epithelia O Schuth, WJ McLean, RA Eatock, SJ Pyott Journal of the Association for Research in Otolaryngology 15, 739-754, 2014 | 25 | 2014 |
Approaches to treat sensorineural hearing loss by hair-cell regeneration: The current state of therapeutic developments and their potential impact on audiological clinical practice AS Hinton, A Yang-Hood, AD Schrader, C Loose, KK Ohlemiller, ... Journal of the American Academy of Audiology 32 (10), 661-669, 2021 | 10 | 2021 |
Methods for controlled proliferation of stem cells/generating inner ear hair cells using gsk-3-alpha inhibitors C Loose, W Mclean, M Harrison US Patent App. 16/080,813, 2019 | 7 | 2019 |
Thermoreversible compositions for administration of therapeutic agents C Loose, W Mclean, M Harrison, MR Jirousek US Patent 10,213,511, 2019 | 7 | 2019 |
1, 5-dihydro-2H-pyrrol-2-one compounds and methods of using same C Loose, B Tait, R Manchanda, W Mclean US Patent 10,383,881, 2019 | 6 | 2019 |
Solubilized compositions for controlled proliferation of stem cells/generating inner ear hair cells using GSK3 inhibitors: III C Loose, W Mclean, M Harrison, MR Jirousek US Patent 10,016,507, 2018 | 6 | 2018 |
Automated western blot analysis of ototoxin-induced prestin burst in the blood after cyclodextrin exposure MS Harrison, BG Driscoll, J Farnsworth, A Hinton, M Peppi, W McLean, ... Otology & Neurotology 44 (9), e653-e659, 2023 | 5 | 2023 |
Methods for controlled proliferation of vestibular stem cells/generating inner ear hair cells using wnt and tgfbeta-inhibition W Mclean US Patent App. 16/080,820, 2019 | 5 | 2019 |
Solubilized compositions for controlled proliferation of stem cells/generating inner ear hair cells using GSK3 inhibitors: I C Loose, W Mclean, M Harrison, MR Jirousek US Patent 10,201,540, 2019 | 4 | 2019 |
Solubilized compositions for controlled proliferation of stem cells/generating inner ear hair cells using a GSK3 inhibitor: I C Loose, W Mclean, M Harrison, MR Jirousek US Patent 11,033,546, 2021 | 3 | 2021 |
Methods for controlled proliferation of stem cells/generating inner ear hair cells using 3-(pyridin-2-yl)-1H-indol-2-ol based compounds C Loose, W Mclean, HD Melissa US Patent 10,220,041, 2019 | 3 | 2019 |
Methods for controlled proliferation of stem cells/generating inner ear hair cells using 3-(pyridin-2-yl)-1H-indol-2-ol based compounds C Loose, W Mclean, HD Melissa US Patent 9,968,615, 2018 | 3 | 2018 |
Methods for controlled proliferation of stem cells/generating inner ear hair cells using 1, 2, 3, 4-tetrahydro-[1, 4] diazepino [6, 7, 1-hi] indolyl based compounds C Loose, W Mclean, HD Melissa US Patent 9,913,848, 2018 | 3 | 2018 |
Toward a true cure for hearing impairment W McLean Science 359 (6380), 1113-1113, 2018 | 3 | 2018 |
Solubilized compositions for controlled proliferation of stem cells/generating inner ear hair cells using a GSK3 inhibitor: IV C Loose, W Mclean, M Harrison, MR Jirousek US Patent 11,260,130, 2022 | 2 | 2022 |