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Megan R Chastney
Megan R Chastney
University of Turku, Turku Bioscience
Email confirmado em utu.fi
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Signal transduction via integrin adhesion complexes
JD Humphries, MR Chastney, JA Askari, MJ Humphries
Current opinion in cell biology 56, 14-21, 2019
2882019
Integrin adhesion complexes
MR Chastney, JRW Conway, J Ivaska
Current Biology 31 (10), R536-R542, 2021
1022021
Topological features of integrin adhesion complexes revealed by multiplexed proximity biotinylation
MR Chastney, C Lawless, JD Humphries, S Warwood, MC Jones, ...
Journal of Cell Biology 219 (8), e202003038, 2020
782020
The role and regulation of integrins in cell migration and invasion
MR Chastney, J Kaivola, VM Leppänen, J Ivaska
Nature Reviews Molecular Cell Biology 26 (2), 147-167, 2025
202025
Proximity labelling identifies pro-migratory endocytic recycling cargo and machinery of the Rab4 and Rab11 families
B Wilson, C Flett, J Gemperle, C Lawless, M Hartshorn, E Hinde, ...
Journal of Cell Science 136 (12), 2023
142023
Focal adhesions contain three specialized actin nanoscale layers
R Kumari, K Ven, M Chastney, SB Kokate, J Peränen, J Aaron, K Kogan, ...
Nature Communications 15 (1), 2547, 2024
11*2024
Multiplexed Proximity Biotinylation Coupled to Mass Spectrometry for Defining Integrin Adhesion Complexes
MR Chastney, C Lawless, MJ Humphries
Current Protocols in Cell Biology 88 (1), e113, 2020
72020
Pancreatic ductal adenocarcinoma cells employ integrin α6β4 to form hemidesmosomes and regulate cell proliferation
JD Humphries, J Zha, J Burns, JA Askari, CR Below, MR Chastney, ...
Matrix Biology 110, 16-39, 2022
62022
SHANK3 depletion leads to ERK signalling overdose and cell death in KRAS-mutant cancers
J Lilja, J Kaivola, JRW Conway, J Vuorio, H Parkkola, P Roivas, M Dibus, ...
Nature Communications 15 (1), 8002, 2024
32024
Restoring mechanophenotype reverts malignant properties of ECM-enriched vocal fold cancer
J Kaivola, K Punovuori, MR Chastney, YA Miroshnikova, H Abdo, ...
bioRxiv, 2024
12024
Regulation of cell dynamics by rapid transport of integrins through the biosynthetic pathway
M Lerche, M Mathieu, L Malerød, NM Pedersen, H Hamidi, M Chastney, ...
bioRxiv, 2022.07. 12.498931, 2022
12022
EPLINα controls integrin recycling from Rab21 endosomes to drive breast cancer cell migration
NZ Jäntti, P Moreno-Layseca, MR Chastney, M Dibus, JRW Conway, ...
bioRxiv, 2024.06. 27.600789, 2024
2024
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Artigos 1–12