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Pierangelo Geppetti
Pierangelo Geppetti
Professore di Farmacologia Clinica
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An endogenous capsaicin-like substance with high potency at recombinant and native vanilloid VR1 receptors
SM Huang, T Bisogno, M Trevisani, A Al-Hayani, L De Petrocellis, F Fezza, ...
Proceedings of the National Academy of Sciences 99 (12), 8400-8405, 2002
12402002
Nitric oxide mediates angiogenesis in vivo and endothelial cell growth and migration in vitro promoted by substance P.
M Ziche, L Morbidelli, E Masini, S Amerini, HJ Granger, CA Maggi, ...
The Journal of clinical investigation 94 (5), 2036-2044, 1994
11551994
Agonists of proteinase-activated receptor 2 induce inflammation by a neurogenic mechanism
M Steinhoff, N Vergnolle, SH Young, M Tognetto, S Amadesi, HS Ennes, ...
Nature medicine 6 (2), 151-158, 2000
11232000
Mast cell-dependent excitation of visceral-nociceptive sensory neurons in irritable bowel syndrome
G Barbara, B Wang, V Stanghellini, R De Giorgio, C Cremon, G Di Nardo, ...
Gastroenterology 132 (1), 26-37, 2007
9582007
4-Hydroxynonenal, an endogenous aldehyde, causes pain and neurogenic inflammation through activation of the irritant receptor TRPA1
M Trevisani, J Siemens, S Materazzi, DM Bautista, R Nassini, B Campi, ...
Proceedings of the National Academy of Sciences 104 (33), 13519-13524, 2007
8872007
Substance p
S Harrison, P Geppetti
The international journal of biochemistry & cell biology 33 (6), 555-576, 2001
7122001
Tachykinins and their receptors: contributions to physiological control and the mechanisms of disease
MS Steinhoff, B von Mentzer, P Geppetti, C Pothoulakis, NW Bunnett
Physiological reviews 94 (1), 265-301, 2014
6622014
Ethanol elicits and potentiates nociceptor responses via the vanilloid receptor-1
M Trevisani, D Smart, MJ Gunthorpe, M Tognetto, M Barbieri, B Campi, ...
Nature neuroscience 5 (6), 546-551, 2002
5262002
Cigarette smoke–induced neurogenic inflammation is mediated by α, β-unsaturated aldehydes and the TRPA1 receptor in rodents
E Andre, B Campi, S Materazzi, M Trevisani, S Amadesi, D Massi, ...
The Journal of clinical investigation 118 (7), 2574-2582, 2008
5042008
Protease-activated receptor 2 sensitizes the capsaicin receptor transient receptor potential vanilloid receptor 1 to induce hyperalgesia
S Amadesi, J Nie, N Vergnolle, GS Cottrell, EF Grady, M Trevisani, ...
Journal of Neuroscience 24 (18), 4300-4312, 2004
4962004
Protease‐activated receptor 2 sensitizes the transient receptor potential vanilloid 4 ion channel to cause mechanical hyperalgesia in mice
AD Grant, GS Cottrell, S Amadesi, M Trevisani, P Nicoletti, S Materazzi, ...
The Journal of physiology 578 (3), 715-733, 2007
4432007
The TGR5 receptor mediates bile acid–induced itch and analgesia
F Alemi, E Kwon, DP Poole, TM Lieu, V Lyo, F Cattaruzza, F Cevikbas, ...
The Journal of clinical investigation 123 (4), 1513-1530, 2013
4092013
Protons: small stimulants of capsaicin-sensitive sensory nerves
S Bevan, P Geppetti
Trends in neurosciences 17 (12), 509-512, 1994
4031994
Protease-activated receptor 2 mediates eosinophil infiltration and hyperreactivity in allergic inflammation of the airway
F Schmidlin, S Amadesi, K Dabbagh, DE Lewis, P Knott, NW Bunnett, ...
The Journal of Immunology 169 (9), 5315-5321, 2002
3932002
Substance P stimulates neovascularization in vivo and proliferation of cultured endothelial cells
M Ziche, L Morbidelli, M Pacini, P Geppetti, G Alessandri, CA Maggi
Microvascular research 40 (2), 264-278, 1990
3681990
Oxaliplatin elicits mechanical and cold allodynia in rodents via TRPA1 receptor stimulation
R Nassini, M Gees, S Harrison, G De Siena, S Materazzi, N Moretto, ...
Pain® 152 (7), 1621-1631, 2011
3542011
Increase in plasma calcitonin gene-related peptide from the extracerebral circulation during nitroglycerin-induced cluster headache attack
M Fanciullacci, M Alessandri, M Figini, P Geppetti, S Michelacci
Pain 60 (2), 119-123, 1995
3381995
Reduced cardiocirculatory complications with unrestrictive visiting policy in an intensive care unit: results from a pilot, randomized trial
S Fumagalli, L Boncinelli, A Lo Nostro, P Valoti, G Baldereschi, M Di Bari, ...
Circulation 113 (7), 946-952, 2006
3312006
The concept of neurogenic inflammation
P Geppetti, R Nassini, S Materazzi, S Benemei
BJU international 101, 2-6, 2008
3152008
Anandamide acts as an intracellular messenger amplifying Ca2+ influx via TRPV1 channels
M van der Stelt, M Trevisani, V Vellani, L De Petrocellis, ...
The EMBO journal 24 (17), 3026-3037, 2005
2962005
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