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Martin Lohse
Martin Lohse
Professor, Universität Würzburg
Email confirmado em isarbioscience.de
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β-Arrestin: a protein that regulates β-adrenergic receptor function
MJ Lohse, JL Benovic, J Codina, MG Caron, RJ Lefkowitz
Science 248 (4962), 1547-1550, 1990
15871990
Altered expression of beta-adrenergic receptor kinase and beta 1-adrenergic receptors in the failing human heart.
M Ungerer, M Böhm, JS Elce, E Erdmann, MJ Lohse
Circulation 87 (2), 454-463, 1993
11421993
What is the role of β-adrenergic signaling in heart failure?
MJ Lohse, S Engelhardt, T Eschenhagen
Circulation research 93 (10), 896-906, 2003
10912003
Progressive hypertrophy and heart failure in β1-adrenergic receptor transgenic mice
S Engelhardt, L Hein, F Wiesmann, MJ Lohse
Proceedings of the National Academy of Sciences 96 (12), 7059-7064, 1999
10121999
Novel single chain cAMP sensors for receptor-induced signal propagation*♦
VO Nikolaev, M Bunemann, L Hein, A Hannawacker, MJ Lohse
Journal of Biological Chemistry 279 (36), 37215-37218, 2004
8732004
The genomic clone G-21 which resembles a β-adrenergic receptor sequence encodes the 5-HT1A receptor
A Fargin, JR Raymond, MJ Lohse, BK Kobilka, MG Caron, RJ Lefkowitz
Nature 335 (6188), 358-360, 1988
8471988
Comparative pharmacology of human adenosine receptor subtypes–characterization of stably transfected receptors in CHO cells
KN Klotz, J Hessling, J Hegler, C Owman, B Kull, BB Fredholm, MJ Lohse
Naunyn-Schmiedeberg's archives of pharmacology 357, 1-9, 1997
8041997
β2-Adrenergic Receptor Redistribution in Heart Failure Changes cAMP Compartmentation
VO Nikolaev, A Moshkov, AR Lyon, M Miragoli, P Novak, H Paur, ...
Science 327 (5973), 1653-1657, 2010
6922010
Persistent cAMP-signals triggered by internalized G-protein–coupled receptors
D Calebiro, VO Nikolaev, MC Gagliani, T De Filippis, C Dees, C Tacchetti, ...
PLoS biology 7 (8), e1000172, 2009
6532009
A FlAsH-based FRET approach to determine G protein–coupled receptor activation in living cells
C Hoffmann, G Gaietta, M Bünemann, SR Adams, S Oberdorff-Maass, ...
Nature methods 2 (3), 171-176, 2005
6352005
G protein–coupled receptor oligomerization revisited: functional and pharmacological perspectives
S Ferré, V Casadó, LA Devi, M Filizola, R Jockers, MJ Lohse, G Milligan, ...
Pharmacological reviews 66 (2), 413-434, 2014
6212014
Molecular mechanisms of membrane receptor desensitization
MJ Lohse
Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1179 (2), 171-188, 1993
6151993
Gi protein activation in intact cells involves subunit rearrangement rather than dissociation
M Bünemann, M Frank, MJ Lohse
Proceedings of the National Academy of Sciences 100 (26), 16077-16082, 2003
5522003
Multiple pathways of rapid beta 2-adrenergic receptor desensitization. Delineation with specific inhibitors.
MJ Lohse, JL Benovic, MG Caron, RJ Lefkowitz
Journal of Biological Chemistry 265 (6), 3209b, 1990
5491990
Measurement of the millisecond activation switch of G protein–coupled receptors in living cells
JP Vilardaga, M Bünemann, C Krasel, M Castro, MJ Lohse
Nature biotechnology 21 (7), 807-812, 2003
5392003
Direct evidence for a β1-adrenergic receptor–directed autoimmune attack as a cause of idiopathic dilated cardiomyopathy
R Jahns, V Boivin, L Hein, S Triebel, CE Angermann, G Ertl, MJ Lohse
The Journal of clinical investigation 113 (10), 1419-1429, 2004
5232004
Single-molecule analysis of fluorescently labeled G-protein–coupled receptors reveals complexes with distinct dynamics and organization
D Calebiro, F Rieken, J Wagner, T Sungkaworn, U Zabel, A Borzi, ...
Proceedings of the National Academy of Sciences 110 (2), 743-748, 2013
5102013
Building a new conceptual framework for receptor heteromers
S Ferré, R Baler, M Bouvier, MG Caron, LA Devi, T Durroux, K Fuxe, ...
Nature chemical biology 5 (3), 131-134, 2009
4972009
8-Cyclopentyl-1,3-dipropylxanthine (DPCPX) — a selective high affinity antagonist radioligand for A1 adenosine receptors
MJ Lohse, KN Klotz, J Lindenborn-Fotinos, M Reddington, U Schwabe, ...
Naunyn-Schmiedeberg's archives of pharmacology 336, 204-210, 1987
4891987
Sequestration and recycling of beta 2-adrenergic receptors permit receptor resensitization.
S Pippig, S Andexinger, MJ Lohse
Molecular pharmacology 47 (4), 666-676, 1995
4841995
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