| Enzymatic amplification of β-globin genomic sequences and restriction site analysis for diagnosis of sickle cell anemia RK Saiki, S Scharf, F Faloona, KB Mullis, GT Horn, HA Erlich, N Arnheim Science 230 (4732), 1350-1354, 1985 | 13986 | 1985 |
| Process for amplifying, detecting, and/or-cloning nucleic acid sequences KB Mullis, HA Erlich, N Arnheim, GT Horn, RK Saiki, SJ Scharf US Patent 4,683,195, 1987 | 7373 | 1987 |
| Most human carcinomas of the exocrine pancreas contain mutant cK-ras genes C Almoguera, D Shibata, K Forrester, J Martin, N Arnheim, M Perucho Cell 53 (4), 549-554, 1988 | 2826 | 1988 |
| Whole genome amplification from a single cell: implications for genetic analysis. L Zhang, X Cui, K Schmitt, R Hubert, W Navidi, N Arnheim Proceedings of the National Academy of Sciences 89 (13), 5847-5851, 1992 | 1365 | 1992 |
| Detection of a specific mitochondrial DNA deletion in tissues of older humans GA Cortopassi, N Arnheim Nucleic acids research 18 (23), 6927-6933, 1990 | 981 | 1990 |
| Involvement of mouse Mlh1 in DNA mismatch repair and meiotic crossing over SM Baker, AW Plug, TA Prolla, CE Bronner, AC Harris, X Yao, DM Christie, ... Nature genetics 13 (3), 336-342, 1996 | 978 | 1996 |
| Amplification and analysis of DNA sequences in single human sperm and diploid cells H Li, UB Gyllensten, X Cui, RK Saiki, HA Erlich, N Arnheim Nature 335 (6189), 414-417, 1988 | 928 | 1988 |
| Detection of human papilloma virus in paraffin-embedded tissue using the polymerase chain reaction. DK Shibata, N Arnheim, WJ Martin The Journal of experimental medicine 167 (1), 225-230, 1988 | 882 | 1988 |
| Hydroxylated quantum dots as luminescent probes for in situ hybridization S Pathak, SK Choi, N Arnheim, ME Thompson Journal of the American Chemical Society 123 (17), 4103-4104, 2001 | 859 | 2001 |
| A pattern of accumulation of a somatic deletion of mitochondrial DNA in aging human tissues. GA Cortopassi, D Shibata, NW Soong, N Arnheim Proceedings of the National Academy of Sciences 89 (16), 7370-7374, 1992 | 850 | 1992 |
| A simple method for site-directed mutagenesis using the polymerase chain reaction A Hemsley, N Arnheim, MD Toney, G Cortopassi, DJ Galas Nucleic acids research 17 (16), 6545-6551, 1989 | 834 | 1989 |
| Concerted evolution of multigene families. AN Arnheim N | 724 | 1983 |
| Male mice defective in the DNA mismatch repair gene PMS2 exhibit abnormal chromosome synapsis in meiosis SM Baker, CE Bronner, L Zhang, AW Plug, M Robatzek, G Warren, ... Cell 82 (2), 309-319, 1995 | 678 | 1995 |
| Polyglutamine-expanded human huntingtin transgenes induce degeneration of Drosophila photoreceptor neurons GR Jackson, I Salecker, X Dong, X Yao, N Arnheim, PW Faber, ... Neuron 21 (3), 633-642, 1998 | 676 | 1998 |
| Molecular evidence for genetic exchanges among ribosomal genes on nonhomologous chromosomes in man and apes. N Arnheim, M Krystal, R Schmickel, G Wilson, O Ryder, E Zimmer Proceedings of the National Academy of Sciences 77 (12), 7323-7327, 1980 | 621 | 1980 |
| Length mutations in human mitochondrial DNA: direct sequencing of enzymatically amplified DNA LA Wrischnik, RG Higuchi, M Stoneking, HA Erlich, N Arnheim, AC Wilson Nucleic acids research 15 (2), 529-541, 1987 | 541 | 1987 |
| Advancing age has differential effects on DNA damage, chromatin integrity, gene mutations, and aneuploidies in sperm AJ Wyrobek, B Eskenazi, S Young, N Arnheim, I Tiemann-Boege, ... Proceedings of the National Academy of Sciences 103 (25), 9601-9606, 2006 | 523 | 2006 |
| Mosaicism for a specific somatic mitochondrial DNA mutation in adult human brain N Wei Soong, DR Hinton, G Cortopassi, N Arnheim Nature genetics 2 (4), 318-323, 1992 | 517 | 1992 |
| Extension of base mispairs by Taq DNA polymerase: implications for single nucleotide discrimination in PCR MM Huang, N Arnheim, MF Goodman Nucleic acids research 20 (17), 4567-4573, 1992 | 490 | 1992 |
| Polymerase chain reaction strategy N Arnheim, H Erlich Annual review of biochemistry 61 (1), 131-156, 1992 | 477 | 1992 |
Jonathan M GoodmanProfessor of Chemistry, University of CambridgeEmail confirmado em cam.ac.uk