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Rachel M. Lee
Rachel M. Lee
Bioimage Data Analyst, Advanced Imaging Center, Janelia Research Campus
Email confirmado em janelia.hhmi.org - Página inicial
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Direct observation of the conformational states of PIEZO1
EM Mulhall, A Gharpure, RM Lee, AE Dubin, JS Aaron, KL Marshall, ...
Nature 620 (7976), 1117-1125, 2023
662023
Quantifying stretching and rearrangement in epithelial sheet migration
RM Lee, DH Kelley, KN Nordstrom, NT Ouellette, W Losert
New Journal of Physics 15 (2), 025036, 2013
502013
The Mechanical Microenvironment in Breast Cancer
SJP Pratt, RM Lee, SS Martin
Cancers 12 (6), 1452, 2020
482020
Collective cell migration has distinct directionality and speed dynamics
Y Zhang, G Xu, RM Lee, Z Zhu, J Wu, S Liao, G Zhang, Y Sun, A Mogilner, ...
Cellular and molecular life sciences 74, 3841-3850, 2017
462017
Controlled gating of lysenin pores
D Fologea, E Krueger, R Lee, M Naglak, Y Mazur, R Henry, G Salamo
Biophysical chemistry 146 (1), 25-29, 2010
332010
Quantifying topography-guided actin dynamics across scales using optical flow
RM Lee, L Campanello, MJ Hourwitz, P Alvarez, A Omidvar, JT Fourkas, ...
Molecular biology of the cell 31 (16), 1753-1764, 2020
292020
Mechanoactivation of NOX2-generated ROS elicits persistent TRPM8 Ca2+ signals that are inhibited by oncogenic KRas
SJP Pratt, RM Lee, KT Chang, EO Hernández-Ochoa, DA Annis, EC Ory, ...
Proceedings of the National Academy of Sciences 117 (42), 26008-26019, 2020
282020
Multivalent ions control the transport through lysenin channels
D Fologea, E Krueger, R Al Faori, R Lee, YI Mazur, R Henry, M Arnold, ...
Biophysical chemistry 152 (1-3), 40-45, 2010
282010
Microtubule disruption reduces metastasis more effectively than primary tumor growth
KN Thompson, JA Ju, EC Ory, SJP Pratt, RM Lee, TJ Mathias, KT Chang, ...
Breast Cancer Research 24 (1), 13, 2022
242022
When light meets biology–how the specimen affects quantitative microscopy
MA Reiche, JS Aaron, U Boehm, MC DeSantis, CM Hobson, S Khuon, ...
Journal of Cell Science 135 (6), jcs259656, 2022
222022
Distinct roles of tumor associated mutations in collective cell migration
RM Lee, MI Vitolo, W Losert, SS Martin
Scientific Reports 11 (1), 1-12, 2021
222021
Partial thermal imidization of polyelectrolyte multilayer cell tethering surfaces (TetherChip) enables efficient cell capture and microtentacle fixation for circulating tumor …
JA Ju, CJ Lee, KN Thompson, EC Ory, RM Lee, TJ Mathias, SJP Pratt, ...
Lab on a Chip 20 (16), 2872-2888, 2020
182020
Collective cell migration over long time scales reveals distinct phenotypes
RM Lee, CH Stuelten, CA Parent, W Losert
Convergent Science Physical Oncology 2 (2), 025001, 2016
182016
Single-Cell Tracking of Breast Cancer Cells Enables Prediction of Sphere Formation from Early Cell Divisions
PC Bailey, RM Lee, MI Vitolo, SJP Pratt, E Ory, K Chakrabarti, CJ Lee, ...
iScience 8, 29-39, 2018
172018
Real-time scratch assay reveals mechanisms of early calcium signaling in breast cancer cells in response to wounding
SJP Pratt, EO Hernández-Ochoa, RM Lee, EC Ory, JS Lyons, HC Joca, ...
Oncotarget 9 (38), 25008, 2018
172018
Lysophosphatidic acid regulates the motility of MCF10CA1a breast cancer cell sheets via two opposing signaling pathways
CH Stuelten, RM Lee, W Losert, CA Parent
Cellular Signalling, 2018
172018
Believing is seeing–the deceptive influence of bias in quantitative microscopy
RM Lee, LR Eisenman, S Khuon, JS Aaron, TL Chew
Journal of Cell Science 137 (1), jcs261567, 2024
102024
Propagation dynamics of electrotactic motility in large epithelial cell sheets
Y Zhang, G Xu, J Wu, RM Lee, Z Zhu, Y Sun, K Zhu, W Losert, S Liao, ...
Iscience 25 (10), 105136, 2022
102022
Inferring single-cell behaviour from large-scale epithelial sheet migration patterns
RM Lee, H Yue, WJ Rappel, W Losert
Journal of The Royal Society Interface 14 (130), 20170147, 2017
102017
Tubulin Carboxypeptidase Activity Promotes Focal Gelatin Degradation in Breast Tumor Cells and Induces Apoptosis in Breast Epithelial Cells That Is Overcome by Oncogenic Signaling
TJ Mathias, JA Ju, RM Lee, KN Thompson, ML Mull, DA Annis, KT Chang, ...
Cancers 14 (7), 1707, 2022
72022
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Artigos 1–20