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Colin K. Choi
Colin K. Choi
Postdoc, Bioengineering, Boston University & Wyss Institute at Harvard University
Email confirmado em bu.edu
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Actin and α-actinin orchestrate the assembly and maturation of nascent adhesions in a myosin II motor-independent manner
CK Choi*, M Vicente-Manzanares*, J Zareno, LA Whitmore, A Mogilner, ...
Nature cell biology 10 (9), 1039-1050, 2008
10652008
Integrins in cell migration–the actin connection
M Vicente-Manzanares, CK Choi, AR Horwitz
Journal of cell science 122 (2), 199-206, 2009
6282009
Biomimetic model to reconstitute angiogenic sprouting morphogenesis in vitro
DHT Nguyen*, SC Stapleton*, MT Yang, SS Cha, CK Choi, PA Galie, ...
Proceedings of the National Academy of Sciences 110 (17), 6712-6717, 2013
5502013
Regulation of protrusion, adhesion dynamics, and polarity by myosins IIA and IIB in migrating cells
M Vicente-Manzanares, J Zareno, L Whitmore, CK Choi, AF Horwitz
Journal of Cell Biology 176 (5), 573-580, 2007
5052007
Fluid shear stress threshold regulates angiogenic sprouting
PA Galie, DHT Nguyen, CK Choi, DM Cohen, PA Janmey, CS Chen
Proceedings of the National Academy of Sciences 111 (22), 7968-7973, 2014
4462014
Multidimensional traction force microscopy reveals out-of-plane rotational moments about focal adhesions
WR Legant*, CK Choi*, JS Miller, L Shao, L Gao, E Betzig, CS Chen
Proceedings of the National Academy of Sciences 110 (3), 881-886, 2013
3372013
Matrix degradability controls multicellularity of 3D cell migration
B Trappmann*, BM Baker*, WJ Polacheck, CK Choi, JA Burdick, CS Chen
Nature communications 8 (1), 371, 2017
2812017
A DNA-based molecular probe for optically reporting cellular traction forces
BL Blakely, CE Dumelin, B Trappmann, LM McGregor, CK Choi, ...
Nature methods 11 (12), 1229, 2014
2362014
Stoichiometry of molecular complexes at adhesions in living cells
MA Digman, PW Wiseman, C Choi, AR Horwitz, E Gratton
Proceedings of the National Academy of Sciences 106 (7), 2170-2175, 2009
2012009
Extracellular matrix alignment dictates the organization of focal adhesions and directs uniaxial cell migration
WY Wang, AT Pearson, ML Kutys, CK Choi, MA Wozniak, BM Baker, ...
APL bioengineering 2 (4), 2018
1172018
Cross-correlated fluctuation analysis reveals phosphorylation-regulated paxillin-FAK complexes in nascent adhesions
CK Choi, J Zareno, MA Digman, E Gratton, AR Horwitz
Biophysical Journal 100 (3), 583, 2011
1102011
Rac1 is deactivated at integrin activation sites through an IQGAP1–filamin-A–RacGAP1 pathway
G Jacquemet, MR Morgan, A Byron, JD Humphries, CK Choi, CS Chen, ...
Journal of cell science 126 (18), 4121-4135, 2013
922013
A proteomic approach reveals integrin activation state-dependent control of microtubule cortical targeting
A Byron, JA Askari, JD Humphries, G Jacquemet, EJ Koper, S Warwood, ...
Nature communications 6 (1), 6135, 2015
812015
Stochastic model of integrin-mediated signaling and adhesion dynamics at the leading edges of migrating cells
M Cirit, M Krajcovic, CK Choi, ES Welf, AF Horwitz, JM Haugh
PLoS computational biology 6 (2), e1000688, 2010
742010
Engineered materials and the cellular microenvironment: a strengthening interface between cell biology and bioengineering
CK Choi, MT Breckenridge, CS Chen
Trends in cell biology 20 (12), 705-714, 2010
732010
Tensin1 requires protein phosphatase-1α in addition to RhoGAP DLC-1 to control cell polarization, migration, and invasion
EH Hall, AE Daugherty, CK Choi, AF Horwitz, DL Brautigan
Journal of Biological Chemistry 284 (50), 34713-34722, 2009
652009
Myosin IIA–mediated forces regulate multicellular integrity during vascular sprouting
C Yoon*, CK Choi*, S Stapleton*, T Mirabella, C Howes, L Dong, J King, ...
Molecular biology of the cell 30 (16), 1974-1984, 2019
312019
Short-term shear stress induces rapid actin dynamics in living endothelial cells
CK Choi, BP Helmke
Molecular & cellular biomechanics: MCB 5 (4), 247, 2008
292008
Applications of microphysiological systems to disease models in the biopharmaceutical industry: opportunities and challenges
O Irrechukwu, R Yeager, R David, J Ekert, A Saravanakumar, CK Choi
ALTEX-Alternatives to animal experimentation 40 (3), 485-518, 2023
132023
Assessment of a 3D neural spheroid model to detect pharmaceutical-induced neurotoxicity
Q Wang, JD Cohen, T Yukawa, H Estrella, C Leonard, J Nunes, C Choi, ...
ALTEX-Alternatives to animal experimentation, 2022
122022
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