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Denise Monack
Denise Monack
Professor of Microbiology and Immunology
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Cryopyrin activates the inflammasome in response to toxins and ATP
S Mariathasan, DS Weiss, K Newton, J McBride, K O'Rourke, ...
Nature 440 (7081), 228-232, 2006
35852006
Differential activation of the inflammasome by caspase-1 adaptors ASC and Ipaf
S Mariathasan, K Newton, DM Monack, D Vucic, DM French, WP Lee, ...
Nature 430 (6996), 213-218, 2004
21542004
Microbiota-liberated host sugars facilitate post-antibiotic expansion of enteric pathogens
KM Ng, JA Ferreyra, SK Higginbottom, JB Lynch, PC Kashyap, ...
Nature 502 (7469), 96-99, 2013
11172013
Inflammasome adaptors and sensors: intracellular regulators of infection and inflammation
S Mariathasan, DM Monack
Nature Reviews Immunology 7 (1), 31-40, 2007
11122007
The Salmonella invasin SipB induces macrophage apoptosis by binding to caspase-1
D Hersh, DM Monack, MR Smith, N Ghori, S Falkow, A Zychlinsky
Proceedings of the National Academy of Sciences 96 (5), 2396-2401, 1999
10301999
Macrophage‐dependent induction of the Salmonella pathogenicity island 2 type III secretion system and its role in intracellular survival
DM Cirillo, RH Valdivia, DM Monack, S Falkow
Molecular microbiology 30 (1), 175-188, 1998
8021998
Salmonella typhimurium invasion induces apoptosis in infected macrophages.
DM Monack, B Raupach, AE Hromockyj, S Falkow
Proceedings of the National Academy of Sciences 93 (18), 9833-9838, 1996
7831996
Persistent bacterial infections: the interface of the pathogen and the host immune system
DM Monack, A Mueller, S Falkow
Nature Reviews Microbiology 2 (9), 747-765, 2004
7742004
Two physically, functionally, and developmentally distinct peritoneal macrophage subsets
EEB Ghosn, AA Cassado, GR Govoni, T Fukuhara, Y Yang, DM Monack, ...
Proceedings of the National Academy of Sciences 107 (6), 2568-2573, 2010
7652010
The NeST long ncRNA controls microbial susceptibility and epigenetic activation of the interferon-γ locus
JA Gomez, OL Wapinski, YW Yang, JF Bureau, S Gopinath, DM Monack, ...
Cell 152 (4), 743-754, 2013
7362013
Differential requirement for Caspase-1 autoproteolysis in pathogen-induced cell death and cytokine processing
P Broz, J von Moltke, JW Jones, RE Vance, DM Monack
Cell host & microbe 8 (6), 471-483, 2010
7272010
Redundant roles for inflammasome receptors NLRP3 and NLRC4 in host defense against Salmonella
P Broz, K Newton, M Lamkanfi, S Mariathasan, VM Dixit, DM Monack
Journal of Experimental Medicine 207 (8), 1745-1755, 2010
6772010
Newly described pattern recognition receptors team up against intracellular pathogens
P Broz, DM Monack
Nature Reviews Immunology 13 (8), 551-565, 2013
6262013
Caspase-11 increases susceptibility to Salmonella infection in the absence of caspase-1
P Broz, T Ruby, K Belhocine, DM Bouley, N Kayagaki, VM Dixit, ...
Nature 490 (7419), 288-291, 2012
6172012
Absent in melanoma 2 is required for innate immune recognition of Francisella tularensis
JW Jones, N Kayagaki, P Broz, T Henry, K Newton, K O'Rourke, S Chan, ...
Proceedings of the National Academy of Sciences 107 (21), 9771-9776, 2010
5962010
Critical function for Naip5 in inflammasome activation by a conserved carboxy-terminal domain of flagellin
KL Lightfield, J Persson, SW Brubaker, CE Witte, J Von Moltke, ...
Nature immunology 9 (10), 1171-1178, 2008
5652008
Yersinia signals macrophages to undergo apoptosis and YopJ is necessary for this cell death
DM Monack, J Mecsas, N Ghori, S Falkow
Proceedings of the National Academy of Sciences 94 (19), 10385-10390, 1997
5551997
Salmonella typhimurium Persists within Macrophages in the Mesenteric Lymph Nodes of Chronically Infected Nramp1+/+ Mice and Can Be Reactivated by …
DM Monack, DM Bouley, S Falkow
The Journal of experimental medicine 199 (2), 231-241, 2004
5462004
Innate immunity against Francisella tularensis is dependent on the ASC/caspase-1 axis
S Mariathasan, DS Weiss, VM Dixit, DM Monack
The Journal of experimental medicine 202 (8), 1043-1049, 2005
5282005
A gut commensal-produced metabolite mediates colonization resistance to Salmonella infection
A Jacobson, L Lam, M Rajendram, F Tamburini, J Honeycutt, T Pham, ...
Cell host & microbe 24 (2), 296-307. e7, 2018
4702018
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