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Todd Golub
Todd Golub
Broad Institute
E-mail confirmado em broadinstitute.org
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Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles
A Subramanian, P Tamayo, VK Mootha, S Mukherjee, BL Ebert, ...
Proceedings of the National Academy of Sciences 102 (43), 15545-15550, 2005
484182005
Molecular classification of cancer: class discovery and class prediction by gene expression monitoring
TR Golub, DK Slonim, P Tamayo, C Huard, M Gaasenbeek, JP Mesirov, ...
science 286 (5439), 531-537, 1999
157231999
MicroRNA expression profiles classify human cancers
J Lu, G Getz, EA Miska, E Alvarez-Saavedra, J Lamb, D Peck, ...
nature 435 (7043), 834-838, 2005
120042005
PGC-1α-responsive genes involved in oxidative phosphorylation are coordinately downregulated in human diabetes
VK Mootha, CM Lindgren, KF Eriksson, A Subramanian, S Sihag, J Lehar, ...
Nature genetics 34 (3), 267-273, 2003
105572003
Integrated genomic analysis identifies clinically relevant subtypes of glioblastoma characterized by abnormalities in PDGFRA, IDH1, EGFR, and NF1
RGW Verhaak, KA Hoadley, E Purdom, V Wang, Y Qi, MD Wilkerson, ...
Cancer cell 17 (1), 98-110, 2010
81582010
The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity
J Barretina, G Caponigro, N Stransky, K Venkatesan, AA Margolin, S Kim, ...
Nature 483 (7391), 603-607, 2012
81462012
Comprehensive genomic characterization defines human glioblastoma genes and core pathways
Cancer Genome Atlas Research Network Tissue source sites: Duke University ...
Nature 455 (7216), 1061-1068, 2008
75882008
Mutational heterogeneity in cancer and the search for new cancer-associated genes
MS Lawrence, P Stojanov, P Polak, GV Kryukov, K Cibulskis, ...
Nature 499 (7457), 214-218, 2013
60062013
The Connectivity Map: using gene-expression signatures to connect small molecules, genes, and disease
J Lamb, ED Crawford, D Peck, JW Modell, IC Blat, MJ Wrobel, J Lerner, ...
science 313 (5795), 1929-1935, 2006
54052006
The landscape of somatic copy-number alteration across human cancers
R Beroukhim, CH Mermel, D Porter, G Wei, S Raychaudhuri, J Donovan, ...
Nature 463 (7283), 899-905, 2010
44242010
Interpreting patterns of gene expression with self-organizing maps: methods and application to hematopoietic differentiation
P Tamayo, D Slonim, J Mesirov, Q Zhu, S Kitareewan, E Dmitrovsky, ...
Proceedings of the National Academy of Sciences 96 (6), 2907-2912, 1999
40001999
Activating mutation in the tyrosine kinase JAK2 in polycythemia vera, essential thrombocythemia, and myeloid metaplasia with myelofibrosis
RL Levine, M Wadleigh, J Cools, BL Ebert, G Wernig, BJP Huntly, ...
Cancer cell 7 (4), 387-397, 2005
39002005
Discovery and saturation analysis of cancer genes across 21 tumour types
MS Lawrence, P Stojanov, CH Mermel, JT Robinson, LA Garraway, ...
Nature 505 (7484), 495-501, 2014
33482014
Diffuse large B-cell lymphoma outcome prediction by gene-expression profiling and supervised machine learning
MA Shipp, KN Ross, P Tamayo, AP Weng, JL Kutok, RCT Aguiar, ...
Nature medicine 8 (1), 68-74, 2002
32002002
Gene expression correlates of clinical prostate cancer behavior
D Singh, PG Febbo, K Ross, DG Jackson, J Manola, C Ladd, P Tamayo, ...
Cancer cell 1 (2), 203-209, 2002
31662002
Classification of human lung carcinomas by mRNA expression profiling reveals distinct adenocarcinoma subclasses
A Bhattacharjee, WG Richards, J Staunton, C Li, S Monti, P Vasa, C Ladd, ...
Proceedings of the National Academy of Sciences 98 (24), 13790-13795, 2001
31442001
A molecular signature of metastasis in primary solid tumors
S Ramaswamy, KN Ross, ES Lander, TR Golub
Nature genetics 33 (1), 49-54, 2003
30312003
The mutational landscape of head and neck squamous cell carcinoma
N Stransky, AM Egloff, AD Tward, AD Kostic, K Cibulskis, A Sivachenko, ...
science 333 (6046), 1157-1160, 2011
28792011
Prediction of central nervous system embryonal tumour outcome based on gene expression
SL Pomeroy, P Tamayo, M Gaasenbeek, LM Sturla, M Angelo, ...
Nature 415 (6870), 436-442, 2002
28612002
A next generation connectivity map: L1000 platform and the first 1,000,000 profiles
A Subramanian, R Narayan, SM Corsello, DD Peck, TE Natoli, X Lu, ...
Cell 171 (6), 1437-1452. e17, 2017
28532017
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